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View Structure Prediction Details

Protein: QRI1
Organism: Saccharomyces cerevisiae
Length: 477 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for QRI1.

Description E-value Query
Range
Subject
Range
QRI1 - UDP-N-acetylglucosamine pyrophosphorylase, catalyzes the formation of UDP-N-acetylglucosamine (UDP-G...
UAP1_YEAST - UDP-N-acetylglucosamine pyrophosphorylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
0.0 [1..477] [1..477]
gi|14424722, gi|... - gi|19923739|ref|NP_003106.2| UDP-N-acteylglucosamine pyrophosphorylase 1 [Homo sapiens], gi|14424722...
0.0 [1..477] [3..494]
gi|17028454 - gi|17028454|gb|AAH17547.1| UDP-N-acetylglucosamine pyrophosphorylase 1 [Mus musculus]
0.0 [1..477] [3..510]
UAP2_ARATH - UDP-N-acetylglucosamine diphosphorylase 2 OS=Arabidopsis thaliana GN=GLCNAC1PUT2 PE=1 SV=1
0.0 [2..468] [31..494]
UAP1_CANAX - UDP-N-acetylglucosamine pyrophosphorylase OS=Candida albicans GN=UAP1 PE=1 SV=1
0.0 [2..474] [7..486]
SPBC1289.08 - UDP-N-acetylglucosamine diphosphorylase
UAP1_SCHPO - Probable UDP-N-acetylglucosamine pyrophosphorylase OS=Schizosaccharomyces pombe (strain 972 / ATCC 2...
0.0 [5..473] [9..474]
CE27831 - status:Confirmed UniProt:Q18493 protein_id:CAA91270.2
0.0 [12..473] [70..525]

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Predicted Domain #1
Region A:
Residues: [1-80]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDTKQLFIE AGQSQLFHNW ESLSRKDQEE LLSNLEQISS KRSPAKLLED CQNAIKFSLA  60
   61 NSSKDTGVEI SPLPPTSYES 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.673 a.39.1 EF-hand
View Download 0.434 d.58.5 GlnB-like
View Download 0.561 a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.540 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.540 f.17.1 F1F0 ATP synthase subunit C
View Download 0.419 a.64.1 Saposin
View Download 0.416 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.383 a.24.4 Hemerythrin
View Download 0.372 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.370 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.338 a.3.1 Cytochrome c
View Download 0.334 a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.330 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.325 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.313 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.306 a.39.1 EF-hand
View Download 0.304 a.3.1 Cytochrome c
View Download 0.299 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.294 d.146.1 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
View Download 0.292 a.61.1 Retroviral matrix proteins
View Download 0.286 c.78.2 Aspartate/glutamate racemase
View Download 0.280 i.1.1 Ribosome and ribosomal fragments
View Download 0.280 d.58.7 RNA-binding domain, RBD
View Download 0.276 a.64.1 Saposin
View Download 0.274 d.58.13 Anticodon-binding domain of PheRS
View Download 0.271 a.144.2 Ribosomal protein L20
View Download 0.269 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.267 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.263 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.261 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.260 a.77.1 DEATH domain
View Download 0.256 d.58.26 GHMP Kinase, C-terminal domain
View Download 0.250 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.250 g.14.1 Kringle-like
View Download 0.250 a.29.2 Bromodomain
View Download 0.249 d.58.7 RNA-binding domain, RBD
View Download 0.248 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.248 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.247 a.74.1 Cyclin-like
View Download 0.245 a.74.1 Cyclin-like
View Download 0.245 a.5.6 Hypothetical protein MTH1615
View Download 0.242 a.24.17 Group V grass pollen allergen
View Download 0.242 a.126.1 Serum albumin-like
View Download 0.242 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.240 a.112.1 Description not found.
View Download 0.236 d.150.1 4'-phosphopantetheinyl transferase
View Download 0.229 a.21.1 HMG-box
View Download 0.227 a.64.1 Saposin
View Download 0.227 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.223 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.223 d.58.3 Protease propeptides/inhibitors
View Download 0.222 a.4.5 "Winged helix" DNA-binding domain
View Download 0.221 a.85.1 Hemocyanin, N-terminal domain
View Download 0.217 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.215 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.215 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.214 a.118.8 TPR-like
View Download 0.212 a.4.1 Homeodomain-like
View Download 0.208 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.208 a.141.1 Frizzled cystein-rich domain
View Download 0.205 a.24.17 Group V grass pollen allergen
View Download 0.202 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.200 d.95.2 Homing endonucleases
View Download 0.200 d.58.5 GlnB-like

Predicted Domain #2
Region A:
Residues: [81-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LIGNSKKENE YWRLGLEAIG KGEVAVILMA GGQGTRLGSS QPKGCYDIGL PSKKSLFQIQ  60
   61 AEKLIRLQDM VKDKKVEIPW YIMTSGPTRA ATEAYFQEHN YFGLNKEQIT FFNQGTLPAF 120
  121 DLTGKHFLMK DPVNLSQSPD GNGGLYRAIK ENKLNEDFDR RGIKHVYMYC VDNVLSKIAD 180
  181 PVFIGFAIKH GFELATKAVR KRDAHESVGL IATKNEKPCV IEYSEISNEL AEAKDKDGLL 240
  241 KLRAGNIVNH YYLVDLLKRD LDQWCENMPY HIAKKKIPAY DSV

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.71
Match: 1hm0A
Description: N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [364-477]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGKYTKPTEP NGIKLEQFIF DVFDTVPLNK FGCLEVDRCK EFSPLKNGPG SKNDNPETSR  60
   61 LAYLKLGTSW LEDAGAIVKD GVLVEVSSKL SYAGENLSQF KGKVFDRSGI VLEK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.495 0.085 UDP-N-acetylglucosamine biosynthetic process a.74.1 Cyclin-like
View Download 0.565 0.039 UDP-N-acetylglucosamine biosynthetic process a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.604 0.031 UDP-N-acetylglucosamine biosynthetic process c.78.2 Aspartate/glutamate racemase
View Download 0.621 N/A N/A d.67.2 Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain
View Download 0.457 N/A N/A c.78.2 Aspartate/glutamate racemase
View Download 0.448 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.448 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.434 N/A N/A a.74.1 Cyclin-like
View Download 0.425 N/A N/A d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.422 N/A N/A d.58.27 Translational regulator protein regA
View Download 0.410 N/A N/A d.58.26 GHMP Kinase, C-terminal domain
View Download 0.406 N/A N/A a.74.1 Cyclin-like
View Download 0.403 N/A N/A a.24.4 Hemerythrin
View Download 0.397 N/A N/A c.78.2 Aspartate/glutamate racemase
View Download 0.391 N/A N/A d.80.1 Tautomerase/MIF
View Download 0.380 N/A N/A a.1.1 Globin-like
View Download 0.372 N/A N/A d.38.1 Thioesterase/thiol ester dehydrase-isomerase
View Download 0.355 N/A N/A d.80.1 Tautomerase/MIF
View Download 0.354 N/A N/A a.130.1 Chorismate mutase II
View Download 0.344 N/A N/A a.40.1 Calponin-homology domain, CH-domain
View Download 0.341 N/A N/A d.92.1 Metalloproteases ("zincins"), catalytic domain
View Download 0.335 N/A N/A f.16.1 Gated mechanosensitive channel
View Download 0.317 N/A N/A a.1.1 Globin-like
View Download 0.311 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.303 N/A N/A a.1.1 Globin-like
View Download 0.302 N/A N/A c.52.1 Restriction endonuclease-like
View Download 0.296 N/A N/A c.30.1 PreATP-grasp domain
View Download 0.295 N/A N/A a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.293 N/A N/A d.58.22 TRADD, N-terminal domain
View Download 0.289 N/A N/A d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain
View Download 0.288 N/A N/A c.23.5 Flavoproteins
View Download 0.275 N/A N/A d.58.41 SEA domain
View Download 0.274 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.273 N/A N/A c.23.1 CheY-like
View Download 0.270 N/A N/A c.44.2 Enzyme IIB-cellobiose
View Download 0.262 N/A N/A c.16.1 Lumazine synthase
View Download 0.251 N/A N/A c.26.1 Nucleotidylyl transferase
View Download 0.242 N/A N/A d.58.11 EF-G/eEF-2 domains III and V
View Download 0.238 N/A N/A d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain
View Download 0.238 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.237 N/A N/A c.44.1 Phosphotyrosine protein phosphatases I
View Download 0.228 N/A N/A a.74.1 Cyclin-like
View Download 0.222 N/A N/A a.1.1 Globin-like
View Download 0.216 N/A N/A a.47.2 t-snare proteins
View Download 0.214 N/A N/A d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.212 N/A N/A a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.211 N/A N/A c.30.1 PreATP-grasp domain
View Download 0.211 N/A N/A a.74.1 Cyclin-like
View Download 0.206 N/A N/A d.52.4 YhbC-like, N-terminal domain
View Download 0.203 N/A N/A a.26.1 4-helical cytokines
View Download 0.203 N/A N/A a.74.1 Cyclin-like
View Download 0.202 N/A N/A d.92.1 Metalloproteases ("zincins"), catalytic domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle