| Protein: | POL3 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1097 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for POL3.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..1097] | [1..1093] |
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0.0 | [45..1097] | [13..1097] |
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0.0 | [45..1097] | [13..1095] |
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0.0 | [69..1097] | [49..1098] |
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0.0 | [45..1097] | [13..1095] |
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0.0 | [69..1097] | [49..1099] |
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Region A: Residues: [1-75] |
1 11 21 31 41 51
| | | | | |
1 MSEKRSLPMV DVKIDDEDTP QLEKKIKRQS IDHGVGSEPV STIEIIPSDS FRKYNSQGFK 60
61 AKDTDLMGTQ LESTF
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| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.677 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.593 | d.88.1 | SRF-like |
| View | Download | 0.445 | a.2.7 | tRNA-binding arm |
| View | Download | 0.452 | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.502 | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.441 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.440 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.400 | d.58.2 | Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain |
| View | Download | 0.389 | d.237.1 | Hypothetical protein YjiA, C-terminal domain |
| View | Download | 0.378 | c.23.1 | CheY-like |
| View | Download | 0.375 | d.88.1 | SRF-like |
| View | Download | 0.363 | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.360 | d.58.12 | eEF-1beta-like |
| View | Download | 0.336 | d.230.2 | Flavin-binding protein dodecin |
| View | Download | 0.316 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.314 | d.15.2 | CAD & PB1 domains |
| View | Download | 0.313 | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.290 | d.58.17 | Metal-binding domain |
| View | Download | 0.279 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.279 | a.39.1 | EF-hand |
| View | Download | 0.269 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.269 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.268 | a.58.1 | Chemotaxis receptor methyltransferase CheR, N-terminal domain |
| View | Download | 0.259 | a.4.1 | Homeodomain-like |
| View | Download | 0.237 | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.236 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.224 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.217 | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.208 | a.2.5 | Prefoldin |
|
Region A: Residues: [76-157] |
1 11 21 31 41 51
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1 EQDVSQMEHD MADQEEHDLS SFERKKLPTD FDPSLYDISF QQIDAEQSVL NGIKDENTST 60
61 VVRFFGVTSE GHSVLCNVTG FK
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Region B: Residues: [251-578] |
1 11 21 31 41 51
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1 NIAYTLRLMV DCGIVGMSWI TLPKGKYSMI EPNNRVSSCQ LEVSINYRNL IAHPAEGDWS 60
61 HTAPLRIMSF DIECAGRIGV FPEPEYDPVI QIANVVSIAG AKKPFIRNVF TLNTCSPITG 120
121 SMIFSHATEE EMLSNWRNFI IKVDPDVIIG YNTTNFDIPY LLNRAKALKV NDFPYFGRLK 180
181 TVKQEIKESV FSSKAYGTRE TKNVNIDGRL QLDLLQFIQR EYKLRSYTLN AVSAHFLGEQ 240
241 KEDVHYSIIS DLQNGDSETR RRLAVYCLKD AYLPLRLMEK LMALVNYTEM ARVTGVPFSY 300
301 LLARGQQIKV VSQLFRKCLE IDTVIPNM
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| Detection Method: | |
| Confidence: | 1532.218487 |
| Match: | 1tgoA_ |
| Description: | Exonuclease domain of family B (archaeal and phage) DNA polymerases; T4-like DNA polymerase |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [158-250] |
1 11 21 31 41 51
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1 NYLYVPAPNS SDANDQEQIN KFVHYLNETF DHAIDSIEVV SKQSIWGYSG DTKLPFWKIY 60
61 VTYPHMVNKL RTAFERGHLS FNSWFSNGTT TYD
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Region B: Residues: [579-589] |
1 11 21 31 41 51
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1 QSQASDDQYE G
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Region C: Residues: [611-731] |
1 11 21 31 41 51
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1 SLYPSIMMAH NLCYTTLCNK ATVERLNLKI DEDYVITPNG DYFVTTKRRR GILPIILDEL 60
61 ISARKRAKKD LRDEKDPFKR DVLNGRQLAL KISANSVYGF TGATVGKLPC LAISSSVTAY 120
121 G
|
| Detection Method: | |
| Confidence: | 1532.218487 |
| Match: | 1tgoA_ |
| Description: | Exonuclease domain of family B (archaeal and phage) DNA polymerases; T4-like DNA polymerase |
| Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [590-610] |
1 11 21 31 41 51
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1 ATVIEPIRGY YDVPIATLDF N
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Region B: Residues: [732-833] |
1 11 21 31 41 51
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1 RTMILKTKTA VQEKYCIKNG YKHDAVVVYG DTDSVMVKFG TTDLKEAMDL GTEAAKYVST 60
61 LFKHPINLEF EKAYFPYLLI NKKRYAGLFW TNPDKFDKLD QK
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| Detection Method: | |
| Confidence: | 1532.218487 |
| Match: | 1tgoA_ |
| Description: | Exonuclease domain of family B (archaeal and phage) DNA polymerases; T4-like DNA polymerase |
| Matching Structure (courtesy of the PDB): |
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Region A: Residues: [834-1007] |
1 11 21 31 41 51
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1 GLASVRRDSC SLVSIVMNKV LKKILIERNV DGALAFVRET INDILHNRVD ISKLIISKTL 60
61 APNYTNPQPH AVLAERMKRR EGVGPNVGDR VDYVIIGGND KLYNRAEDPL FVLENNIQVD 120
121 SRYYLTNQLQ NPIISIVAPI IGDKQANGMF VVKSIKINTG SQKGGLMSFI KKVE
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| Detection Method: | |
| Confidence: | 1532.218487 |
| Match: | 1tgoA_ |
| Description: | Exonuclease domain of family B (archaeal and phage) DNA polymerases; T4-like DNA polymerase |
| Matching Structure (courtesy of the PDB): |
|
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Region A: Residues: [1008-1097] |
1 11 21 31 41 51
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1 ACKSCKGPLR KGEGPLCSNC LARSGELYIK ALYDVRDLEE KYSRLWTQCQ RCAGNLHSEV 60
61 LCSNKNCDIF YMRVKVKKEL QEKVEQLSKW
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.777 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.721 | a.7.1 | Spectrin repeat |
| View | Download | 0.795 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.695 | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.741 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.595 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.592 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.548 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.523 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.510 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.500 | a.2.7 | tRNA-binding arm |
| View | Download | 0.490 | a.26.1 | 4-helical cytokines |
| View | Download | 0.437 | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.431 | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.420 | a.2.7 | tRNA-binding arm |
| View | Download | 0.384 | a.47.2 | t-snare proteins |
| View | Download | 0.371 | a.7.1 | Spectrin repeat |
| View | Download | 0.340 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.339 | d.17.4 | NTF2-like |
| View | Download | 0.339 | a.7.8 | GAT domain |
| View | Download | 0.316 | a.2.7 | tRNA-binding arm |
| View | Download | 0.313 | d.19.1 | MHC antigen-recognition domain |
| View | Download | 0.306 | a.3.1 | Cytochrome c |
| View | Download | 0.301 | a.47.2 | t-snare proteins |
| View | Download | 0.301 | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.299 | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.293 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.289 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.283 | f.17.2 | Cytochrome c oxidase subunit II-like, transmembrane region |
| View | Download | 0.279 | a.62.1 | Hepatitis B viral capsid (hbcag) |
| View | Download | 0.261 | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
| View | Download | 0.259 | a.26.1 | 4-helical cytokines |
| View | Download | 0.257 | a.2.7 | tRNA-binding arm |
| View | Download | 0.253 | d.232.1 | Mago nashi protein |
| View | Download | 0.251 | c.55.1 | Actin-like ATPase domain |
| View | Download | 0.247 | a.30.1 | ROP protein |
| View | Download | 0.247 | d.52.1 | Alpha-lytic protease prodomain |
| View | Download | 0.244 | a.24.3 | Cytochromes |
| View | Download | 0.237 | g.44.1 | RING/U-box |
| View | Download | 0.232 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.231 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.226 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.219 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.219 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.213 | a.22.1 | Histone-fold |
| View | Download | 0.212 | a.48.1 | N-terminal domain of cbl (N-cbl) |
| View | Download | 0.212 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.209 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.205 | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.200 | a.112.1 | Description not found. |
