YRC Public Data Repository - Protein Structure Prediction

Protein:	GET3
Organism:	Saccharomyces cerevisiae
Length:	354 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GET3.

Description	E-value	Query Range	Subject Range
GET3_YEAST - ATPase GET3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GET3 PE=1 SV=1 GET3 - Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; subunit of the GET comp... GET3_YEAS7 - ATPase GET3 OS=Saccharomyces cerevisiae (strain YJM789) GN=GET3 PE=3 SV=1 GET3_YEAS1 - ATPase GET3 OS=Saccharomyces cerevisiae (strain RM11-1a) GN=GET3 PE=3 SV=1	3.0E-70	[1..354]	[1..354]
GET3_SCHPO - ATPase get3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=get3 PE=1 SV=1 get3 - GET complex ATPase subunit Get3	9.0E-54	[3..345]	[1..328]
ARSA_PROVB - Putative arsenical pump-driving ATPase OS=Prosthecochloris vibrioformis PE=3 SV=1 gi\|193211943, gi... - gi\|193211943\|ref\|YP_001997896.1\| arsenite-activated ATPase ArsA [Chlorobaculum parvum NCIB 8327], gi...	7.0E-53	[19..345]	[2..315]
ARS1_AQUAE, ARSA... - Putative arsenical pump-driving ATPase 1 OS=Aquifex aeolicus GN=arsA1 PE=3 SV=1, (O66908) Putative a... ARSA1_AQUAE - Putative arsenical pump-driving ATPase 1 OS=Aquifex aeolicus (strain VF5) GN=arsA1 PE=3 SV=1	3.0E-52	[19..352]	[2..331]
asna-1 - ArsA status:Confirmed UniProt:P30632 protein_id:CAA77452.1	1.0E-51	[1..338]	[1..338]
ASNA_DICDI - ATPase ASNA1 homolog OS=Dictyostelium discoideum GN=arsA PE=1 SV=1 gi\|66800287, gi\|... - gi\|66800287\|ref\|XP_629069.1\| arsenite transport subunit A [Dictyostelium discoideum AX4], gi\|6046235...	5.0E-51	[2..347]	[3..325]
tr\|G3HCW3\|G3HCW3... - ATPase Asna1 OS=Cricetulus griseus GN=Asna1 PE=3 SV=1 gi\|34851421, gi\|... - gi\|34851421\|ref\|XP_213848.2\| PREDICTED: similar to arsenic resistance ATPase [Rattus norvegicus], gi... ASNA_MOUSE - ATPase Asna1 OS=Mus musculus GN=Asna1 PE=1 SV=2	8.0E-51	[5..342]	[24..346]
gi\|2905657 - gi\|2905657\|gb\|AAC03551.1\| arsenite translocating ATPase [Homo sapiens]	8.0E-51	[5..342]	[24..346]
gi\|7428325, gi\|6... - pir\|\|F69068 probable arsenical pump-driving ATPase (EC 3.6.1.-) - Methanobacterium thermoautotrophic... ARSA_METTH - Putative arsenical pump-driving ATPase OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 ...	1.0E-49	[11..340]	[7..323]
gi\|13541887, gi\|... - gi\|14325321\|dbj\|BAB60225.1\| anion transporting ATPase [Thermoplasma volcanium GSS1], gi\|13541887\|ref...	2.0E-49	[16..349]	[1..314]

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Predicted Domain #1

Region A:
Residues: [1-354]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLTVEPNLH SLITSTTHKW IFVGGKGGVG KTTSSCSIAI QMALSQPNKQ FLLISTDPAH  60
   61 NLSDAFGEKF GKDARKVTGM NNLSCMEIDP SAALKDMNDM AVSRANNNGS DGQGDDLGSL 120
  121 LQGGALADLT GSIPGIDEAL SFMEVMKHIK RQEQGEGETF DTVIFDTAPT GHTLRFLQLP 180
  181 NTLSKLLEKF GEITNKLGPM LNSFMGAGNV DISGKLNELK ANVETIRQQF TDPDLTTFVC 240
  241 VCISEFLSLY ETERLIQELI SYDMDVNSII VNQLLFAEND QEHNCKRCQA RWKMQKKYLD 300
  301 QIDELYEDFH VVKMPLCAGE IRGLNNLTKF SQFLNKEYNP ITDGKVIYEL EDKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	288.927757
Match:	1f48A_
Description:	Arsenite-translocating ATPase ArsA
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits