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View Structure Prediction Details

Protein: BDF2
Organism: Saccharomyces cerevisiae
Length: 638 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BDF2.

Description E-value Query
Range
Subject
Range
BDF2_YEAST - Bromodomain-containing factor 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=BDF2 PE=...
BDF2 - Protein involved in transcription initiation at TATA-containing promoters; associates with the basal...
0.0 [1..622] [1..622]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
2.0E-88 [109..638] [3..475]
YK82_SCHPO - Bromodomain-containing protein C631.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPA...
SPAC631.02 - bromodomain protein
6.0E-88 [5..629] [78..687]
gi|16905089, gi|... - gi|16905089|ref|NP_473395.1| bromodomain, testis-specific [Mus musculus], gi|13957951|gb|AAK50736.1|...
6.0E-82 [108..627] [1..617]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-81 [56..635] [1..554]

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Predicted Domain #1
Region A:
Residues: [1-121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRTNMDTRH AHSALLAAPQ SATANSRSSN SSSESSSNKN NINVGVGDDS GNVSAVSIDD  60
   61 GPHFRDIFHY GHEENYKLAS SGITNLNSSS HAHQTLSPIS ISNASTPESF PEHPLGLERE 120
  121 T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [122-242]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EPALEAEMEA EELPPHQSKY LLSSIKATKR LKDARPFLKP VDPIALNIPH YFNYVQTPMD  60
   61 LSLIETKLQG NVYHSVEQVT SDFKTMVDNC LNFNGPESSI SSMAKRIQKY FEKKLSAMPP 120
  121 R

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 29.552842
Match: PF00439
Description: Bromodomain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [243-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLPASALKKT SRNRKKNEDM DSPLVIRRSV STTNDNIGES GNREGVSGGR PKRTIHPPKS  60
   61 KDLFDIYENS KPK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.219 0.888 nucleus a.4.1 Homeodomain-like

Predicted Domain #4
Region A:
Residues: [316-445]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKTLQKKFRT CLKILKVLMS KKNSDINFPF LQPVDPIALN LPNYFDVVKN PMDLGTISNN  60
   61 LMNWKYKTID QFVDDLNLVF YNCFQFNPEG NEVHSMGKKL KELFNFHWLE NQDILNEIET 120
  121 DSDLEEDNYS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 131.533179
Match: 1e6iA_
Description: GCN5
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [446-502]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSYSSDDEYD DEDINENDIT NPAIQYLEQK LKKMEVELQQ LKRQELSKLS KERKRKH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.807 0.002 nucleus a.8.1 Bacterial immunoglobulin/albumin-binding domains

Predicted Domain #6
Region A:
Residues: [503-638]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGKTLLRRKA MKHSVDDLKK SITDKINELS DLEMNGMIRI IKNSLPADEI LTSNEDEIEI  60
   61 DLDILDEATI ARIYERYFEK KNNNNSKRKL SGNYSTAPTN KKKKTLKFLE KDEIINNNNY 120
  121 SDSEEDSSDS SDSDSD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle