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View Structure Prediction Details

Protein: PSA1
Organism: Saccharomyces cerevisiae
Length: 361 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PSA1.

Description E-value Query
Range		 Subject
Range
ORFP:3552 - YDL055C, Contig c98 30732-31817 reverse complement
gi|190405065 - gi|190405065|gb|EDV08332.1| GDP-mannose pyrophosphorylase [Saccharomyces cerevisiae RM11-1a]
gi|207346948 - gi|207346948|gb|EDZ73286.1| YDL055Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151941944 - gi|151941944|gb|EDN60300.1| GDP-mannose pyrophosphorylase [Saccharomyces cerevisiae YJM789]
PSA1 - GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from ...
MPG1_YEAST - Mannose-1-phosphate guanyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PS...
 0.0 [1..361] [1..361]
MPG1_CANAL - Mannose-1-phosphate guanyltransferase OS=Candida albicans GN=MPG1 PE=1 SV=1
MPG1_CANAL - Mannose-1-phosphate guanyltransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MPG1 PE...
 0.0 [1..361] [1..362]
MPG1_PICAN - Mannose-1-phosphate guanyltransferase OS=Pichia angusta GN=MPG1 PE=3 SV=1
MPG1_PICAN - Mannose-1-phosphate guanyltransferase OS=Pichia angusta GN=MPG1 PE=3 SV=1
 0.0 [1..361] [1..364]
MPG11_CANGA - Mannose-1-phosphate guanyltransferase 1 OS=Candida glabrata GN=MPG1 PE=1 SV=1
MPG11_CANGA - Mannose-1-phosphate guanyltransferase 1 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 /...
 0.0 [1..361] [1..361]
MPG1_HYPJE - Mannose-1-phosphate guanyltransferase OS=Hypocrea jecorina GN=mpg1 PE=1 SV=1
 0.0 [1..361] [1..364]
gi|114586917, gi... - gi|55620329|ref|XP_516466.1| PREDICTED: GDP-mannose pyrophosphorylase B isoform 3 [Pan troglodytes],...
gi|11761621, gi|... - gi|5052351|gb|AAD38516.1|AF135421_1 GDP-mannose pyrophosphorylase B [Homo sapiens], gi|158256832|dbj...
 0.0 [1..361] [1..360]
mpg1 - mannose-1-phosphate guanyltransferase Mpg1
MPG1_SCHPO - Mannose-1-phosphate guanyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=mpg1...
 0.0 [1..361] [1..363]

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Predicted Domain #1
Region A:
Residues: [1-276] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGLILVGGY GTRLRPLTLT VPKPLVEFGN RPMILHQIEA LANAGVTDIV LAVNYRPEVM  60
   61 VETLKKYEKE YGVNITFSVE TEPLGTAGPL KLAEDVLKKD NSPFFVLNSD VICEYPFKEL 120
  121 ADFHKAHGGK GTIVATKVDE PSKYGVIVHD IATPNLIDRF VEKPKEFVGN RINAGLYILN 180
  181 PEVIDLIEMK PTSIEKETFP ILVEEKQLYS FDLEGFWMDV GQPKDFLSGT VLYLNSLAKR 240
  241 QPKKLATGAN IVGNALIDPT AKISSTAKIG PDVVIG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 238.66807
Match: 1h5rB_
Description: RmlA (RfbA)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mannosyltransferase activity 3.87594044828967 bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity 3.78995004368368 bayes_pls_golite062009
uridylyltransferase activity 3.74072767898515 bayes_pls_golite062009
transferase activity 3.32517438937547 bayes_pls_golite062009
mannose-phosphate guanylyltransferase activity 3.09763291641741 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 2.70047942699289 bayes_pls_golite062009
UTP:glucose-1-phosphate uridylyltransferase activity 2.65167602524122 bayes_pls_golite062009
guanylyltransferase activity 2.62845487806844 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.51696952719873 bayes_pls_golite062009
UTP-monosaccharide-1-phosphate uridylyltransferase activity 2.46432078102948 bayes_pls_golite062009
UDP-glycosyltransferase activity 2.33861720107822 bayes_pls_golite062009
mannose-1-phosphate guanylyltransferase activity 2.30953822963071 bayes_pls_golite062009
catalytic activity 1.88676710996045 bayes_pls_golite062009
nucleotidyltransferase activity 1.50551885980582 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 1.33788133706753 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 1.10309252319727 bayes_pls_golite062009
binding 1.09657219604879 bayes_pls_golite062009
cytidylyltransferase activity 0.983416157001861 bayes_pls_golite062009
glycogenin glucosyltransferase activity 0.968757748180341 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 0.897978517422275 bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity 0.513376694534047 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [277-361] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNVTIGDGVR ITRSVVLCNS TIKNHSLVKS TIVGWNSTVG QWCRLEGVTV LGDDVEVKDE  60
   61 IYINGGKVLP HKSISDNVPK EAIIM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.0
Match: 1qq0A_
Description: gamma-carbonic anhydrase
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle