YRC Public Data Repository - Protein Structure Prediction

Protein:	SIT4
Organism:	Saccharomyces cerevisiae
Length:	311 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIT4.

Description	E-value	Query Range	Subject Range
gi\|119390121 - gi\|119390121\|pdb\|2IE3\|C Chain C, Structure Of The Protein Phosphatase 2a Core Enzyme Bound To Tumor-... PP2AA_RAT - Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Rattus norvegicus GN=Ppp2... PP2AA_MOUSE - Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Mus musculus GN=Ppp2ca PE... gi\|56819 - gi\|56819\|emb\|CAA34166.1\| unnamed protein product [Rattus rattus]	0.0	[1..311]	[5..309]
PP2AA_CHICK - Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Gallus gallus GN=PPP2CA P...	0.0	[2..311]	[6..309]
gi\|67970493, gi\|... - gi\|67970495\|dbj\|BAE01590.1\| unnamed protein product [Macaca fascicularis], gi\|67970493\|dbj\|BAE01589.... PPP2CA - protein phosphatase 2, catalytic subunit, alpha isozyme PP2AA_PIG - Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Sus scrofa GN=PPP2CA PE=2... PP2AA_RABIT - Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Oryctolagus cuniculus GN=... tr\|M3X381\|M3X381... - Serine/threonine-protein phosphatase OS=Felis catus GN=PPP2CA PE=3 SV=1 gi\|109078612 - gi\|109078612\|ref\|XP_001108011.1\| PREDICTED: similar to protein phosphatase 2, catalytic subunit, alp... gi\|89267 - pir\|\|A27430 phosphoprotein phosphatase (EC 3.1.3.16) 2-alpha catalytic chain - pig gi\|168277916 - gi\|168277916\|dbj\|BAG10936.1\| serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform... PP2AA_BOVIN - Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Bos taurus GN=PPP2CA PE=1...	0.0	[2..311]	[6..309]
gi\|50978726, gi\|... - gi\|50978726\|ref\|NP_001003063.1\| type 2A protein phosphatase catalytic subunit [Canis lupus familiari...	0.0	[1..311]	[5..309]
PP2AB_RABIT - Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform OS=Oryctolagus cuniculus GN=P...	0.0	[2..311]	[6..309]
let-92 - serine\/threonine protein phosphatase status:Confirmed UniProt:Q27498 protein_id:CAB01174.1 gi\|187034402, gi... - gi\|39593842\|emb\|CAE62135.1\| Hypothetical protein CBG06179 [Caenorhabditis briggsae], gi\|187034402\|em... FL81_04630-RA - null gi\|157755711 - gi\|157755711\|ref\|XP_001670199.1\| Hypothetical protein CBG06179 [Caenorhabditis briggsae AF16]	0.0	[5..311]	[18..318]
gi\|194765657, gi... - gi\|194765657\|ref\|XP_001964943.1\| GF21831 [Drosophila ananassae], gi\|190617553\|gb\|EDV33077.1\| GF21831... gi\|190662070, gi... - gi\|194862952\|ref\|XP_001970203.1\| GG10501 [Drosophila erecta], gi\|190662070\|gb\|EDV59262.1\| GG10501 [D... gi\|194106967, gi... - gi\|195148104\|ref\|XP_002015014.1\| GL18646 [Drosophila persimilis], gi\|194106967\|gb\|EDW29010.1\| GL1864... gi\|227335 - gi\|227335\|prf\|\|1702219A protein phosphatase 2A gi\|220955558, gi... - gi\|220955558\|gb\|ACL90322.1\| mts-PA [synthetic construct], gi\|220945882\|gb\|ACL85484.1\| mts-PA [synthe... mts-PA, FBpp0310... - The gene microtubule star is referred to in FlyBase by the symbol Dmel\mts (CG7109, FBgn0004177). It... gi\|194129999, gi... - gi\|195339019\|ref\|XP_002036119.1\| GM16609 [Drosophila sechellia], gi\|194129999\|gb\|EDW52042.1\| GM16609... gi\|194174098, gi... - gi\|195471409\|ref\|XP_002087997.1\| GE14639 [Drosophila yakuba], gi\|194174098\|gb\|EDW87709.1\| GE14639 [D... gi\|195577391, gi... - gi\|195577391\|ref\|XP_002078554.1\| GD23492 [Drosophila simulans], gi\|194190563\|gb\|EDX04139.1\| GD23492 ... gi\|198474511, gi... - gi\|198474511\|ref\|XP_002132708.1\| GA25737 [Drosophila pseudoobscura pseudoobscura], gi\|198138424\|gb\|E...	0.0	[2..311]	[6..309]

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Predicted Domain #1

Region A:
Residues: [1-311]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSRGPDEWL ETIKKCQALT ENEMKQLCEM VKELLMEESN IQPVQTPVTV CGDIHGQFHD  60
   61 LLELFRTAGG FPDDINYIFL GDYVDRGYYS LETFTLLMCL KVKYPAKITL VRGNHESRQI 120
  121 TQVYGFYEEC LNKYGSTTVW KYCCQVFDFL TLAAIIDGKI LCVHGGLSPE IRMLDQIRVL 180
  181 SRAQEVPHEG GFSDLLWSDP DNVEAWQVSP RGAGWLFGSK VAREFNHVNG LNLIARAHQL 240
  241 VMEGFKYHFP EKDVVTVWSA PNYCYRCGNV ASVMKVDEDL EPTFKIFSAV PDDYIRESTA 300
  301 NHNNQRAGYF L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	847.218487
Match:	1fjmA_
Description:	Protein phosphatase-1 (PP-1)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits