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View Structure Prediction Details

Protein: TSC13
Organism: Saccharomyces cerevisiae
Length: 310 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TSC13.

Description E-value Query
Range
Subject
Range
TECR_YEAST - Very-long-chain enoyl-CoA reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TSC1...
TSC13 - Enoyl reductase that catalyzes the last step in each cycle of very long chain fatty acid elongation,...
7.0E-85 [1..310] [1..310]
gi|13111809 - gi|13111809|gb|AAH00174.2|AAH00174 Unknown (protein for IMAGE:2901253) [Homo sapiens]
5.0E-83 [5..309] [5..303]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-83 [5..309] [9..307]
TECR_MOUSE - Very-long-chain enoyl-CoA reductase OS=Mus musculus GN=Tecr PE=1 SV=1
9.0E-82 [6..309] [10..307]
Sc2-PA - The gene Sc2 is referred to in FlyBase by the symbol Dmel\Sc2 (CG10849, FBgn0035471). It is a protei...
3.0E-74 [7..309] [11..301]
TECR_ARATH - Very-long-chain enoyl-CoA reductase OS=Arabidopsis thaliana GN=ECR PE=1 SV=1
5.0E-74 [1..309] [1..310]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPITIKSRSK GLRDTEIDLS KKPTLDDVLK KISANNHNIS KYRIRLTYKK ESKQVPVISE  60
   61 SFFQEEADDS MEFFIKDLGP QISWRLVFFC EYLGPVLVHS LFYYLSTIPT VVDRWH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.417 0.086 endoplasmic reticulum membrane b.6.1 Cupredoxins
View Download 0.414 0.083 endoplasmic reticulum membrane b.60.1 Lipocalins
View Download 0.644 0.035 endoplasmic reticulum membrane d.218.1 Nucleotidyltransferase
View Download 0.574 0.031 endoplasmic reticulum membrane c.30.1 PreATP-grasp domain
View Download 0.442 0.011 mitochondrion c.23.4 Succinyl-CoA synthetase domains
View Download 0.409 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.391 N/A N/A c.55.1 Actin-like ATPase domain
View Download 0.383 N/A N/A a.118.8 TPR-like
View Download 0.381 N/A N/A c.59.1 MurD-like peptide ligases, peptide-binding domain
View Download 0.364 N/A N/A d.79.1 YjgF-like
View Download 0.337 N/A N/A c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.310 N/A N/A d.109.1 Actin depolymerizing proteins
View Download 0.304 N/A N/A c.61.1 PRTase-like
View Download 0.304 N/A N/A d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.283 N/A N/A c.97.1 Cytidine deaminase-like
View Download 0.281 N/A N/A a.118.1 ARM repeat
View Download 0.281 N/A N/A d.95.2 Homing endonucleases
View Download 0.278 N/A N/A d.42.1 POZ domain
View Download 0.275 N/A N/A b.60.1 Lipocalins
View Download 0.270 N/A N/A d.15.2 CAD & PB1 domains
View Download 0.253 N/A N/A c.32.1 Tubulin/Dihydroxyacetone kinase nucleotide-binding domain
View Download 0.241 N/A N/A d.15.1 Ubiquitin-like
View Download 0.232 N/A N/A b.1.1 Immunoglobulin
View Download 0.227 N/A N/A d.113.1 Nudix
View Download 0.225 N/A N/A b.60.1 Lipocalins
View Download 0.221 N/A N/A d.58.2 Aspartate carbamoyltransferase, Regulatory-chain, N-terminal domain
View Download 0.216 N/A N/A d.73.1 RuBisCO, small subunit
View Download 0.212 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.210 N/A N/A d.68.4 YhbY-like
View Download 0.206 N/A N/A d.118.1 N-acetylmuramoyl-L-alanine amidase-like
View Download 0.203 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains

Predicted Domain #2
Region A:
Residues: [117-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASSDYNPFL NRVAYFLILG HYGKRLFETL FVHQFSLATM PIFNLFKNCF HYWVLSGLIS  60
   61 FGYFGYGFPF GNAKLFKYYS YLKLDDLSTL IGLFVLSELW NFYCHIKLRL WGDYQKKHGN 120
  121 AKIRVPLNQG IFNLFVAPNY TFEVWSWIWF TFVFKFNLFA VLFLTVSTAQ MYAWAQKKNK 180
  181 KYHTRRAFLI PFVF

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 73.148742
Match: PF02544
Description: 3-oxo-5-alpha-steroid 4-dehydrogenase

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle