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View Structure Prediction Details

Protein: TSC13
Organism: Saccharomyces cerevisiae
Length: 310 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TSC13.

Description E-value Query
Range
Subject
Range
TECR_YEAST - Very-long-chain enoyl-CoA reductase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TSC1...
TSC13 - Enoyl reductase that catalyzes the last step in each cycle of very long chain fatty acid elongation,...
7.0E-85 [1..310] [1..310]
gi|13111809 - gi|13111809|gb|AAH00174.2|AAH00174 Unknown (protein for IMAGE:2901253) [Homo sapiens]
5.0E-83 [5..309] [5..303]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-83 [5..309] [9..307]
TECR_MOUSE - Very-long-chain enoyl-CoA reductase OS=Mus musculus GN=Tecr PE=1 SV=1
9.0E-82 [6..309] [10..307]
Sc2-PA - The gene Sc2 is referred to in FlyBase by the symbol Dmel\Sc2 (CG10849, FBgn0035471). It is a protei...
3.0E-74 [7..309] [11..301]
TECR_ARATH - Very-long-chain enoyl-CoA reductase OS=Arabidopsis thaliana GN=ECR PE=1 SV=1
5.0E-74 [1..309] [1..310]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPITIKSRSK GLRDTEIDLS KKPTLDDVLK KISANNHNIS KYRIRLTYKK ESKQVPVISE  60
   61 SFFQEEADDS MEFFIKDLGP QISWRLVFFC EYLGPVLVHS LFYYLSTIPT VVDRWH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [117-310]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SASSDYNPFL NRVAYFLILG HYGKRLFETL FVHQFSLATM PIFNLFKNCF HYWVLSGLIS  60
   61 FGYFGYGFPF GNAKLFKYYS YLKLDDLSTL IGLFVLSELW NFYCHIKLRL WGDYQKKHGN 120
  121 AKIRVPLNQG IFNLFVAPNY TFEVWSWIWF TFVFKFNLFA VLFLTVSTAQ MYAWAQKKNK 180
  181 KYHTRRAFLI PFVF

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 73.148742
Match: PF02544
Description: 3-oxo-5-alpha-steroid 4-dehydrogenase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle