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View Structure Prediction Details

Protein: ABP1
Organism: Saccharomyces cerevisiae
Length: 592 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ABP1.

Description E-value Query
Range
Subject
Range
NEB - nebulin
1.0E-62 [82..591] [6158..6669]
ABP1 - Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 com...
ABP1_YEAST - Actin-binding protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ABP1 PE=1 SV=4
2.0E-55 [1..592] [1..592]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
5.0E-55 [1..592] [1..592]
gi|13429929 - gi|13429929|dbj|BAB18733.2| nebulin [Gallus gallus]
9.0E-54 [98..591] [1879..2402]
gi|8163674 - gi|8163674|gb|AAF73795.1|AF154026_1 surface protein PspC [Streptococcus pneumoniae]
5.0E-50 [100..499] [79..484]
CG10083-PA - This gene is referred to in FlyBase by the symbol Dmel\CG10083 (CG10083, FBgn0036372). It is a prote...
4.0E-46 [6..592] [3..531]

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Predicted Domain #1
Region A:
Residues: [1-170]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALEPIDYTT HSREIDAEYL KIVRGSDPDT TWLIISPNAK KEYEPESTGS SFHDFLQLFD  60
   61 ETKVQYGLAR VSPPGSDVEK IIIIGWCPDS APLKTRASFA ANFAAVANNL FKGYHVQVTA 120
  121 RDEDDLDENE LLMKISNAAG ARYSIQTSSK QQGKASTPPV KKSFTPSKSP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 677.30103
Match: 1hqz1_
Description: Cofilin-like domain of actin-binding protein abp1p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 7.52071741004022 bayes_pls_golite062009
cytoskeletal protein binding 6.04859625643932 bayes_pls_golite062009
actin filament binding 5.45532510538573 bayes_pls_golite062009
binding 2.27089902377783 bayes_pls_golite062009
protein binding 1.90274942416202 bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding 0.72248054722423 bayes_pls_golite062009
structural constituent of cytoskeleton 0.482954032096802 bayes_pls_golite062009
actin monomer binding 0.224304003054399 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [171-444]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APVSKKEPVK TPSPAPAAKI SSRVNDNNDD DDWNEPELKE RDFDQAPLKP NQSSYKPIGK  60
   61 IDLQKVIAEE KAKEDPRLVQ KPTAAGSKID PSSDIANLKN ESKLKRDSEF NSFLGTTKPP 120
  121 SMTESSLKND DDKVIKGFRN EKSPAQLWAE RKAKQNSGNA ETKAEAPKPE VPEDEPEGEP 180
  181 DVKDLKSKFE GLAASEKEEE EMENKFAPPP KKSEPTIISP KPFSKPQEPV KAEEAEQPKT 240
  241 DYKKIGNPLP GMHIEADNEE EPEENDDDWD DDED

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.4
Match: 1ei3A
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [445-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EAAQPPLPSR NVASGAPVQK EEPEQEEIAP SLPSRNSIPA PKQEEAPEQA PEEEIEEEAE  60
   61 EAAPQLPSRS SAAPPPPPRR ATPEKKPKE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.76
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [534-592]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPWATAEYDY DAAEDNELTF VENDKIINIE FVDDDWWLGE LEKDGSKGLF PSNYVSLGN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 291.522879
Match: 1jo8A_
Description: Actin binding protein ABP1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 4.94949685871786 bayes_pls_golite062009
cytoskeletal protein binding 4.41722924924158 bayes_pls_golite062009
actin filament binding 3.69427077755816 bayes_pls_golite062009
binding 2.49184519104882 bayes_pls_golite062009
protein binding 2.10925438883926 bayes_pls_golite062009
structural constituent of muscle 1.44117328570973 bayes_pls_golite062009
structural molecule activity 0.423179340849406 bayes_pls_golite062009
structural constituent of cytoskeleton 0.371928447183203 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle