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View Structure Prediction Details

Protein: ERS1
Organism: Saccharomyces cerevisiae
Length: 260 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERS1.

Description E-value Query
Range
Subject
Range
ctns-1 - status:Confirmed UniProt:Q09500 protein_id:CAA88102.2
327.0 [0..1] [258..125]
gi|158257470, gi... - gi|72534654|ref|NP_001026851.1| cystinosis, nephropathic isoform 1 [Homo sapiens], gi|23273064|gb|AA...
315.0 [0..4] [250..126]
gi|109112773 - gi|109112773|ref|XP_001089495.1| PREDICTED: cystinosis, nephropathic isoform 1 [Macaca mulatta]
313.0 [0..4] [250..126]
gi|157071195, gi... - gi|164426091|ref|XP_960653.2| hypothetical protein NCU01250 [Neurospora crassa OR74A], gi|157071195|...
gi|16944475 - gi|16944475|emb|CAC28641.2| related to CTNS protein [Neurospora crassa]
308.0 [0..1] [251..7]
gi|85098698 - gi|85098698|ref|XP_960653.1| related to CTNS protein [MIPS] [Neurospora crassa OR74A]
gi|28922165, gi|... - gi|32412526|ref|XP_326743.1| related to CTNS protein [MIPS] [Neurospora crassa], gi|28922165|gb|EAA3...
304.0 [0..1] [251..7]
CTNS_MOUSE - Cystinosin OS=Mus musculus GN=Ctns PE=1 SV=1
304.0 [0..4] [256..126]

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Predicted Domain #1
Region A:
Residues: [1-108]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSLDDILGI VYVTSWSISM YPPIITNWRH KSASAISMDF VMLNTAGYSY LVISIFLQLY  60
   61 CWKMTGDESD LGRPKLTQFD FWYCLHGCLM NVVLLTQVVA GARIWRFP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.858 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.858 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.846 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.846 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.832 a.7.8 GAT domain
View Download 0.832 a.7.8 GAT domain
View Download 0.817 a.159.3 Description not found.
View Download 0.814 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.713 a.7.7 BAG domain
View Download 0.702 a.47.2 t-snare proteins

Predicted Domain #2
Region A:
Residues: [109-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKGHRKMNPW YLRILLASLA IFSLLTVQFM YSNYWYDWHN SRTLAYCNNL FLLKISMSLI  60
   61 KYIPQVTHNS TRKSMDCFPI QGVFLDVTGG IASLLQLIWQ LSNDQGFSLD TFVTNFGKVG 120
  121 LSMVTLIFNF IFIMQWFVYR SRGHDLASEY PL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle