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View Structure Prediction Details

Protein: RRT12
Organism: Saccharomyces cerevisiae
Length: 491 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRT12.

Description E-value Query
Range
Subject
Range
gi|190406474 - gi|190406474|gb|EDV09741.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
RRT12_YEAST - Subtilase-type proteinase RRT12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRT12 PE...
RRT12 - Probable subtilisin-family protease with a role in formation of the dityrosine layer of spore walls;...
0.0 [1..491] [1..491]
gi|171680111 - gi|171680111|ref|XP_001905001.1| unnamed protein product [Podospora anserina]
gi|7400480, gi|1... - gi|7400480|gb|AAC03564.2| subtilisin-like serine protease [Podospora anserina], gi|170939682|emb|CAP...
0.0 [3..422] [27..452]
gi|16215673 - gi|16215673|emb|CAC95047.1| subtilisin-like serine protease PR1H [Metarhizium anisopliae var. acridu...
0.0 [2..434] [27..469]
gi|6624962 - gi|6624962|emb|CAB63913.1| subtilisin-like protease PR1H [Metarhizium anisopliae var. anisopliae]
gi|6624962|emb|C... - subtilisin-like protease PR1H [Metarhizium anisopliae var. anisopliae]
0.0 [3..434] [28..469]
gi|15808807 - gi|15808807|gb|AAL08510.1|AF413106_1 subtilase [Ophiostoma piliferum]
1.0E-99 [4..428] [22..450]
ALP2_ASPFC - Alkaline protease 2 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) GN=alp2 PE=3 SV...
gi|2143220, gi|5... - gi|5139328|emb|CAB45520.1| serine proteinase [Aspergillus fumigatus], gi|2143220|emb|CAA73782.1| cel...
ALP2_ASPFU - Alkaline protease 2 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)...
2.0E-99 [4..443] [28..464]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPQCILISL LVNLAYAEEY LVRFKNPTAF QQFTSNSNRS WRQFIDNKIE KKFSIGSFRG  60
   61 VTMNLSKNLV NKLKKSPLVA DIVPNFRFEA FEGDSVNSAE SSYTF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.045757
Match: 1scjB_
Description: Subtilisin prosegment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [106-425]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NATAKYSYED VEEEQNITYQ PDAPRHLARI SRHYQLPFDV GDKDRYKSWF NYYYEHDYQG  60
   61 QDVNAYIMDT GIFADHPEFE DRVIQGIDLT KEGFGDQNGH GTHVAGLVGS KTYGAAKRVN 120
  121 LVEVKVLGKD GSGEASNVLS GLEFIVEHCT KVSRPQGKKC VANLSLGSFR SPIINMAVEG 180
  181 AIEEGIVFVA AAGNFNLDAY WASPASAENV ITVGAFDDHI DTIAKFSNWG PCVNIFAPGV 240
  241 EIESLSHLNY NDTLILSGTS MSTPIVTGVA AILLSKGIEP EMIAQEIEYL STRNVFHRRT 300
  301 LFFKPSTPNQ ILYNGVDKLD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 473.39794
Match: 1ic6A_
Description: Proteinase K
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.26156746825527 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [426-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPYDDETFPR LNIEAIAKEL EEYNATLQTP MSENLQSGSK LWGWNNDVTL PLGEIRLKRR  60
   61 DFMKNL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.486 d.45.1 ClpS-like
View Download 0.373 a.4.1 Homeodomain-like
View Download 0.575 a.20.1 PGBD-like
View Download 0.410 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.575 a.20.1 PGBD-like
View Download 0.486 d.45.1 ClpS-like
View Download 0.469 a.159.2 FF domain
View Download 0.469 a.159.2 FF domain
View Download 0.410 a.60.6 DNA polymerase beta, N-terminal domain-like
View Download 0.373 a.4.1 Homeodomain-like
View Download 0.355 a.39.1 EF-hand
View Download 0.329 d.58.17 Metal-binding domain
View Download 0.311 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.274 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.265 a.112.1 Description not found.
View Download 0.257 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.249 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.238 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.236 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.232 a.4.1 Homeodomain-like
View Download 0.229 a.2.2 Ribosomal protein L29 (L29p)
View Download 0.227 a.144.1 PABC (PABP) domain
View Download 0.227 a.5.6 Hypothetical protein MTH1615
View Download 0.226 a.64.1 Saposin
View Download 0.224 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.223 a.4.5 "Winged helix" DNA-binding domain
View Download 0.222 d.54.1 Enolase N-terminal domain-like
View Download 0.218 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.218 a.30.1 ROP protein
View Download 0.213 a.5.6 Hypothetical protein MTH1615
View Download 0.212 d.58.7 RNA-binding domain, RBD
View Download 0.207 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.207 a.144.1 PABC (PABP) domain
View Download 0.205 d.45.1 ClpS-like
View Download 0.205 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.205 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.202 a.112.1 Description not found.
View Download 0.202 a.24.13 Domain of the SRP/SRP receptor G-proteins


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle