YRC Public Data Repository - Protein Structure Prediction

Protein:	RRT12
Organism:	Saccharomyces cerevisiae
Length:	491 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRT12.

Description	E-value	Query Range	Subject Range
gi\|190406474 - gi\|190406474\|gb\|EDV09741.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] RRT12_YEAST - Subtilase-type proteinase RRT12 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRT12 PE... RRT12 - Probable subtilisin-family protease with a role in formation of the dityrosine layer of spore walls;...	0.0	[1..491]	[1..491]
gi\|171680111 - gi\|171680111\|ref\|XP_001905001.1\| unnamed protein product [Podospora anserina] gi\|7400480, gi\|1... - gi\|7400480\|gb\|AAC03564.2\| subtilisin-like serine protease [Podospora anserina], gi\|170939682\|emb\|CAP...	0.0	[3..422]	[27..452]
gi\|16215673 - gi\|16215673\|emb\|CAC95047.1\| subtilisin-like serine protease PR1H [Metarhizium anisopliae var. acridu...	0.0	[2..434]	[27..469]
gi\|6624962 - gi\|6624962\|emb\|CAB63913.1\| subtilisin-like protease PR1H [Metarhizium anisopliae var. anisopliae] gi\|6624962\|emb\|C... - subtilisin-like protease PR1H [Metarhizium anisopliae var. anisopliae]	0.0	[3..434]	[28..469]
gi\|15808807 - gi\|15808807\|gb\|AAL08510.1\|AF413106_1 subtilase [Ophiostoma piliferum]	1.0E-99	[4..428]	[22..450]
ALP2_ASPFC - Alkaline protease 2 OS=Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) GN=alp2 PE=3 SV... gi\|2143220, gi\|5... - gi\|5139328\|emb\|CAB45520.1\| serine proteinase [Aspergillus fumigatus], gi\|2143220\|emb\|CAA73782.1\| cel... ALP2_ASPFU - Alkaline protease 2 OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)...	2.0E-99	[4..443]	[28..464]

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Predicted Domain #1

Region A:
Residues: [1-105]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPQCILISL LVNLAYAEEY LVRFKNPTAF QQFTSNSNRS WRQFIDNKIE KKFSIGSFRG  60
   61 VTMNLSKNLV NKLKKSPLVA DIVPNFRFEA FEGDSVNSAE SSYTF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	7.045757
Match:	1scjB_
Description:	Subtilisin prosegment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [106-425]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NATAKYSYED VEEEQNITYQ PDAPRHLARI SRHYQLPFDV GDKDRYKSWF NYYYEHDYQG  60
   61 QDVNAYIMDT GIFADHPEFE DRVIQGIDLT KEGFGDQNGH GTHVAGLVGS KTYGAAKRVN 120
  121 LVEVKVLGKD GSGEASNVLS GLEFIVEHCT KVSRPQGKKC VANLSLGSFR SPIINMAVEG 180
  181 AIEEGIVFVA AAGNFNLDAY WASPASAENV ITVGAFDDHI DTIAKFSNWG PCVNIFAPGV 240
  241 EIESLSHLNY NDTLILSGTS MSTPIVTGVA AILLSKGIEP EMIAQEIEYL STRNVFHRRT 300
  301 LFFKPSTPNQ ILYNGVDKLD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	473.39794
Match:	1ic6A_
Description:	Proteinase K
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.26156746825527	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [426-491]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPYDDETFPR LNIEAIAKEL EEYNATLQTP MSENLQSGSK LWGWNNDVTL PLGEIRLKRR  60
   61 DFMKNL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: