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View Structure Prediction Details

Protein: FEN2
Organism: Saccharomyces cerevisiae
Length: 512 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FEN2.

Description E-value Query
Range		 Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 2.0E-74 [1..501] [1..526]
STP1_ARATH - Sugar transport protein 1 OS=Arabidopsis thaliana GN=STP1 PE=1 SV=2
 1.0E-73 [28..468] [17..485]
VGLU2_RAT - Vesicular glutamate transporter 2 OS=Rattus norvegicus GN=Slc17a6 PE=1 SV=1
 1.0E-73 [4..485] [39..522]
STC_RICCO - Sugar carrier protein C OS=Ricinus communis GN=STC PE=2 SV=1
 3.0E-73 [30..468] [21..487]
ENSPTRT00000047022 - null
SLC17A6 - solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
 1.0E-72 [2..485] [37..522]
gi|115470211, gi... - gi|50508995|dbj|BAD31944.1| putative monosaccharide transport protein MST1 [Oryza sativa Japonica Gr...
gi|125556956 - gi|125556956|gb|EAZ02492.1| hypothetical protein OsI_24597 [Oryza sativa Indica Group]
gi|11991114 - gi|11991114|dbj|BAB19864.1| monosaccharide transporter 3 [Oryza sativa]
 4.0E-72 [28..469] [17..486]

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Predicted Domain #1
Region A:
Residues: [1-220] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKESKSITQ HEVERESVSS KRAIKKRLLL FKIDLFVLSF VCLQYWINYV DRVGFTNAYI  60
   61 SGMKEDLKMV GNDLTVSNTV FMIGYIVGMV PNNLMLLCVP PRIWLSFCTF AWGLLTLGMY 120
  121 KVTSFKHICA IRFFQALFES CTFSGTHFVL GSWYKEDELP IRSAIFTGSG LVGSMFSGFM 180
  181 QTSIFTHLNG RNGLAGWRWL FIIDFCITLP IAIYGFIFFP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [261-512] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DWSTIPRVLK RWHWWMFSLV WVLGGENLGF ASNSTFALWL QNQKYTLAQR NNYPSGIFAV  60
   61 GIVSTLCSAV YMSKIPRARH WHVSVFISLV MVIVAVLIRA DPLNPKVVFS AQYLGGVAYA 120
  121 GQAVFFSWAN IICHADLQER AIVLASMNMF SGAVNAWWSI LFFASDMVPK FERGCYALLA 180
  181 TAISSGIVSV VIRSLQIKEN LSKKQVPYID ANDMPGEDDD DDNQDNENDG DDESMEVELH 240
  241 NEEMAEISNP FR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.69897
Match: 1ja5A_
Description: No description for 1ja5A_ was found.

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 5.21742729128468 bayes_pls_golite062009
ion transmembrane transporter activity 4.31748220369305 bayes_pls_golite062009
transporter activity 4.09176719149278 bayes_pls_golite062009
anion transmembrane transporter activity 3.74166040263114 bayes_pls_golite062009
cation transmembrane transporter activity 3.60627834007397 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transporter activity 3.3426261924492 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 2.17838823008408 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.3181781780038 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
phosphate transmembrane transporter activity 0.312628600969375 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [221-260] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLPDQTSAVS KFSMTRYIFN EQELHYARRR LPARDESTRL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.69897
Match: 1ja5A_
Description: No description for 1ja5A_ was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle