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View Structure Prediction Details

Protein: VAC17
Organism: Saccharomyces cerevisiae
Length: 423 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VAC17.

Description E-value Query
Range
Subject
Range
VAC17 - Phosphoprotein involved in vacuole inheritance; degraded in late M phase of the cell cycle; acts as ...
VAC17_YEAST - vacuole-related protein 17 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VAC17 PE=1 SV...
0.0 [1..423] [1..423]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-97 [229..423] [1..195]
gi|3717965 - gi|3717965|emb|CAA21052.1| EG:114D9.2 [Drosophila melanogaster]
0.01 [8..97] [294..371]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATQALEDIT ERLLIRSQEA ILQLDLWIQR QQRSSICQTT DQESLDKLSQ QYNQYMSQLN  60
   61 SLYVRSESVR DKLSKEQQRR LITEDNEHQR IEDLVREFQD ITLRLNELAT VPNEAPNDSP 120
  121 QSQSTRSSLG SFQPRPLKII ERQRLCMV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.923 0.872 vacuolar membrane a.47.2 t-snare proteins
View Download 0.871 0.004 vacuole inheritance a.7.7 BAG domain
View Download 0.900 0.001 receptor activity f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.898 N/A N/A a.47.2 t-snare proteins
View Download 0.838 N/A N/A a.24.2 Aspartate receptor, ligand-binding domain
View Download 0.820 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.780 N/A N/A a.25.1 Ferritin-like
View Download 0.762 N/A N/A a.7.8 GAT domain
View Download 0.755 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.729 N/A N/A a.7.1 Spectrin repeat
View Download 0.729 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.713 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.702 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.679 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.651 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.621 N/A N/A a.2.1 GreA transcript cleavage protein, N-terminal domain
View Download 0.595 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.578 N/A N/A f.17.1 F1F0 ATP synthase subunit C
View Download 0.570 N/A N/A a.7.1 Spectrin repeat
View Download 0.568 N/A N/A a.25.1 Ferritin-like
View Download 0.553 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.550 N/A N/A a.19.1 Fertilization protein
View Download 0.528 N/A N/A a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.526 N/A N/A f.15.1 Small-conductance potassium channel
View Download 0.515 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.505 N/A N/A d.67.3 Ribosome recycling factor, RRF
View Download 0.494 N/A N/A a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.493 N/A N/A a.24.3 Cytochromes
View Download 0.480 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.478 N/A N/A i.11.1 Computational models partly based on NMR data
View Download 0.473 N/A N/A a.7.1 Spectrin repeat
View Download 0.467 N/A N/A a.26.1 4-helical cytokines
View Download 0.457 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.443 N/A N/A a.47.1 STAT
View Download 0.413 N/A N/A a.24.1 Apolipoprotein
View Download 0.402 N/A N/A a.26.1 4-helical cytokines
View Download 0.401 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.396 N/A N/A a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.389 N/A N/A a.7.1 Spectrin repeat
View Download 0.385 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.384 N/A N/A a.7.1 Spectrin repeat
View Download 0.380 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.379 N/A N/A a.24.3 Cytochromes
View Download 0.375 N/A N/A a.26.1 4-helical cytokines
View Download 0.373 N/A N/A a.7.1 Spectrin repeat
View Download 0.360 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.360 N/A N/A a.1.1 Globin-like
View Download 0.355 N/A N/A d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.354 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.350 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.349 N/A N/A f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.344 N/A N/A a.24.3 Cytochromes
View Download 0.336 N/A N/A a.87.1 DBL homology domain (DH-domain)
View Download 0.332 N/A N/A a.2.7 tRNA-binding arm
View Download 0.327 N/A N/A a.26.1 4-helical cytokines
View Download 0.327 N/A N/A c.43.1 CoA-dependent acyltransferases
View Download 0.313 N/A N/A a.87.1 DBL homology domain (DH-domain)
View Download 0.302 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.300 N/A N/A a.26.1 4-helical cytokines
View Download 0.286 N/A N/A a.87.1 DBL homology domain (DH-domain)
View Download 0.285 N/A N/A d.110.4 SNARE-like
View Download 0.283 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.278 N/A N/A a.26.1 4-helical cytokines
View Download 0.269 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.265 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.265 N/A N/A a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.265 N/A N/A c.92.2 "Helical backbone" metal receptor
View Download 0.264 N/A N/A a.72.1 Functional domain of the splicing factor Prp18
View Download 0.255 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.251 N/A N/A a.1.1 Globin-like
View Download 0.249 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.248 N/A N/A f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.245 N/A N/A a.47.2 t-snare proteins
View Download 0.244 N/A N/A a.39.1 EF-hand
View Download 0.239 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.229 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.226 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.218 N/A N/A a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.215 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.210 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.207 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.207 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.203 N/A N/A a.24.12 Outer surface protein C (OspC)
View Download 0.202 N/A N/A a.48.2 Transferrin receptor ectodomain, C-terminal domain
View Download 0.202 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits

Predicted Domain #2
Region A:
Residues: [149-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPSKPPKKSV GFNPINEVDC PSKTNSLPCS PKKQPARNRT LRAAKSHDTG LNKSKKPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.228 d.58.7 RNA-binding domain, RBD
View Download 0.244 d.58.8 Viral DNA-binding domain
View Download 0.252 a.60.3 C-terminal domain of RNA polymerase alpha subunit

Predicted Domain #3
Region A:
Residues: [207-423]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSDTYESFFK NRQRLSLTFF DEMDDEDFDS DQDTIILPNI STPPHVGVTA KGAEFEPLRR  60
   61 YNSHESILSN KPAPSKSLNL GSFSASFFRP SNPTFGTSIS NVQVNCHPTV AATMAPSRNG 120
  121 PRISSSKALL SSFIARSDTH TVKENNTNLK HASFMDKFNS SLSTISESFQ SKRGRKNKGM 180
  181 NEERISNHNV AQEQKNNMDI SVSIEELQDA LNTELLF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle