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View Structure Prediction Details

Protein: PDI1
Organism: Saccharomyces cerevisiae
Length: 522 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PDI1.

Description E-value Query
Range
Subject
Range
PDI_YEAST - Protein disulfide-isomerase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PDI1 PE=1 SV...
PDI1 - Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, es...
0.0 [1..522] [1..522]
PDIA1_RABIT - Protein disulfide-isomerase OS=Oryctolagus cuniculus GN=P4HB PE=2 SV=1
0.0 [8..497] [1..488]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..493] [1..493]
PDI_ASPNG - Protein disulfide-isomerase OS=Aspergillus niger GN=pdiA PE=2 SV=1
0.0 [8..522] [1..515]
gi|5326749 - gi|5326749|gb|AAD42032.1|AF075246_1 protein disulfide isomerase precursor [Kluyveromyces marxianus]
0.0 [15..496] [14..491]
gi|5650705, gi|4... - gi|5650705|emb|CAB51612.1| protein disulfide isomerase [Kluyveromyces lactis], gi|49641377|emb|CAH01...
gi|50304577, gi|... - gi|50304577|ref|XP_452244.1| unnamed protein product [Kluyveromyces lactis], gi|49641377|emb|CAH0109...
0.0 [12..496] [11..491]

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Predicted Domain #1
Region A:
Residues: [1-142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFSAGAVLS WSSLLLASSV FAQQEAVAPE DSAVVKLATD SFNEYIQSHD LVLAEFFAPW  60
   61 CGHCKNMAPE YVKAAETLVE KNITLAQIDC TENQDLCMEH NIPGFPSLKI FKNSDVNNSI 120
  121 DYEGPRTAEA IVQFMIKQSQ PA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 239.67837
Match: 1mek__
Description: Protein disulfide isomerase, PDI
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [143-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VAVVADLPAY LANETFVTPV IVQSGKIDAD FNATFYSMAN KHFNDYDFVS AENADDDFKL  60
   61 SIYLPSAMDE PVVYNGKKAD IADADVFEKW LQVEALPYFG EIDGSVFAQY VESGLPLGYL 120
  121 FYNDEEELEE YKPLFTELAK KNRGLMNFVS IDARKFGRHA GNLNMKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.0
Match: 1bjx__
Description: Protein disulfide isomerase, PDI
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [310-370]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QFPLFAIHDM TEDLKYGLPQ LSEEAFDELS DKIVLESKAI ESLVKDFLKG DASPIVKSQE  60
   61 I

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [371-522]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FENQDSSVFQ LVGKNHDEIV NDPKKDVLVL YYAPWCGHCK RLAPTYQELA DTYANATSDV  60
   61 LIAKLDHTEN DVRGVVIEGY PTIVLYPGGK KSESVVYQGS RSLDSLFDFI KENGHFDVDG 120
  121 KALYEEAQEK AAEEADADAE LADEEDAIHD EL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 94.67837
Match: 1t7pB_
Description: Thioredoxin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle