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View Structure Prediction Details

Protein: RRP7
Organism: Saccharomyces cerevisiae
Length: 297 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RRP7.

Description E-value Query
Range
Subject
Range
RRP7_YEAST - Ribosomal RNA-processing protein 7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRP7 ...
RRP7 - Essential protein involved in rRNA processing and ribosome biogenesis
gi|151943798 - gi|151943798|gb|EDN62098.1| ribosomal RNA processing protein [Saccharomyces cerevisiae YJM789]
gi|190406415 - gi|190406415|gb|EDV09682.1| ribosomal RNA processing protein 7 [Saccharomyces cerevisiae RM11-1a]
gi|207347369 - gi|207347369|gb|EDZ73563.1| YCL031Cp-like protein [Saccharomyces cerevisiae AWRI1631]
0.0 [1..297] [1..297]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-72 [1..178] [1..178]
SPBC776.17 - rRNA processing protein Rrp7
RRP7_SCHPO - Ribosomal RNA-processing protein 7 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=rrp7 PE...
3.0E-61 [34..296] [22..254]
gi|4185815 - gi|4185815|gb|AAD09198.1| beta-lactamase [Shuttle vector pCS4-14]
2.0E-60 [1..149] [1..149]
gi|10176898 - gi|10176898|dbj|BAB10130.1| unnamed protein product [Arabidopsis thaliana]
1.0E-23 [167..296] [182..342]

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Predicted Domain #1
Region A:
Residues: [1-152]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIEDISAMK NGFIVVPFKL PDHKALPKSQ EASLHFMFAK RHQSSNSNES DCLFLVNLPL  60
   61 LSNIEHMKKF VGQLCGKYDT VSHVEELLYN DEFGLHEVDL SALTSDLMSS TDVNEKRYTP 120
  121 RNTALLKFVD AASINNCWNA LKKYSNLHAK HP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.417 0.044 nucleolus f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.413 0.011 nucleolus c.23.4 Succinyl-CoA synthetase domains
View Download 0.405 0.011 nucleolus a.24.14 FAT domain of focal adhesion kinase
View Download 0.550 0.010 nucleolus a.63.1 Apolipophorin-III
View Download 0.394 0.007 nucleolus a.7.4 Smac/diablo
View Download 0.394 N/A N/A a.26.1 4-helical cytokines
View Download 0.392 N/A N/A f.1.5 Exotoxin A, middle domain
View Download 0.363 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.352 N/A N/A a.1.1 Globin-like
View Download 0.333 N/A N/A c.53.2 beta-carbonic anhydrase, cab
View Download 0.333 N/A N/A a.26.1 4-helical cytokines
View Download 0.330 N/A N/A a.79.1 Antitermination factor NusB
View Download 0.325 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.317 N/A N/A d.54.1 Enolase N-terminal domain-like
View Download 0.304 N/A N/A a.1.1 Globin-like
View Download 0.299 N/A N/A a.90.1 Transcription factor STAT-4 N-domain
View Download 0.299 N/A N/A a.74.1 Cyclin-like
View Download 0.289 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.288 N/A N/A a.77.1 DEATH domain
View Download 0.278 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.264 N/A N/A c.26.3 UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
View Download 0.264 N/A N/A a.25.1 Ferritin-like
View Download 0.249 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.245 N/A N/A a.116.1 GTPase activation domain, GAP
View Download 0.244 N/A N/A a.116.1 GTPase activation domain, GAP
View Download 0.238 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.237 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.236 N/A N/A a.7.8 GAT domain
View Download 0.233 N/A N/A d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.228 N/A N/A a.116.1 GTPase activation domain, GAP
View Download 0.226 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.225 N/A N/A d.79.1 YjgF-like
View Download 0.215 N/A N/A a.24.9 alpha-catenin/vinculin

Predicted functions:

Term Confidence Notes
RNA binding 5.63242063989137 bayes_pls_golite062009
mRNA binding 3.87784929382714 bayes_pls_golite062009
nucleic acid binding 3.55052626921306 bayes_pls_golite062009
binding 3.3324591601331 bayes_pls_golite062009
3.14079080441249 bayes_pls_golite062009
single-stranded RNA binding 1.9439583927206 bayes_pls_golite062009
poly-pyrimidine tract binding 1.58538594745054 bayes_pls_golite062009
structural molecule activity 1.30816853575581 bayes_pls_golite062009
protein binding 1.26544376923141 bayes_pls_golite062009
transcription regulator activity 1.10029555513317 bayes_pls_golite062009
DNA binding 0.984725930713243 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.762984801550668 bayes_pls_golite062009
snoRNA binding 0.749770142991192 bayes_pls_golite062009
transcription factor activity 0.255891228964936 bayes_pls_golite062009
ligase activity 0.189138561929496 bayes_pls_golite062009
snRNA binding 0.168885334268568 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [153-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NELFEWTYTT PSFTTFVNFY KPLDIDYLKE DIHTHMAIFE QREAQAQEDV QSSIVDEDGF  60
   61 TLVVGKNTKS LNSIRKKILN KNPLSKHENK AKPISNIDKK AKKDFYRFQV RERKKQEINQ 120
  121 LLSKFKEDQE RIKVMKAKRK FNPYT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.903 0.421 nucleolus a.25.1 Ferritin-like
View Download 0.691 N/A N/A a.25.1 Ferritin-like
View Download 0.397 N/A N/A a.25.1 Ferritin-like
View Download 0.351 N/A N/A a.25.1 Ferritin-like
View Download 0.344 N/A N/A a.4.1 Homeodomain-like
View Download 0.312 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.281 N/A N/A a.25.1 Ferritin-like
View Download 0.279 N/A N/A f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.277 N/A N/A a.19.1 Fertilization protein
View Download 0.273 N/A N/A a.22.1 Histone-fold
View Download 0.267 N/A N/A d.19.1 MHC antigen-recognition domain
View Download 0.239 N/A N/A a.87.1 DBL homology domain (DH-domain)
View Download 0.231 N/A N/A a.22.1 Histone-fold
View Download 0.216 N/A N/A a.25.1 Ferritin-like
View Download 0.215 N/A N/A a.25.1 Ferritin-like
View Download 0.211 N/A N/A a.91.1 Regulator of G-protein signalling, RGS
View Download 0.210 N/A N/A d.19.1 MHC antigen-recognition domain
View Download 0.204 N/A N/A a.2.5 Prefoldin


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle