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View Structure Prediction Details

Protein: PGS1
Organism: Saccharomyces cerevisiae
Length: 521 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGS1.

Description E-value Query
Range
Subject
Range
PGPS1_YEAST - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase OS=Saccharomyces cerevisiae (stra...
gi|207347342 - gi|207347342|gb|EDZ73542.1| YCL004Wp-like protein [Saccharomyces cerevisiae AWRI1631]
PGS1 - Phosphatidylglycerolphosphate synthase, catalyzes the synthesis of phosphatidylglycerolphosphate fro...
0.0 [1..521] [1..521]
PGPS1_SACPS - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase OS=Saccharomyces pastorianus GN=P...
0.0 [1..521] [1..521]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [30..507] [1..482]
gi|19386924 - gi|19386924|gb|AAL87040.1|AF411101_1 silencer-associated factor [Mus musculus]
0.0 [51..520] [41..512]
PGPS1_CRIGR - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial OS=Cricetulus gris...
0.0 [51..520] [81..552]
gi|220948928, gi... - gi|220957696|gb|ACL91391.1| CG7718-PA [synthetic construct], gi|220948928|gb|ACL87007.1| CG7718-PA [...
CG7718-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7718 (CG7718, FBgn0038649). It is a protein...
1.0E-88 [51..520] [49..493]
SPBP18G5.02 - CDP-diacylglycerol-glycerol-3-phosphate3-phosphatidyltransferase
PGPS1_SCHPO - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase OS=Schizosaccharomyces pombe (str...
1.0E-87 [45..521] [9..534]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTRLLQLTR PHYRLLSLPL QKPFNIKRQM SAANPSPFGN YLNTITKSLQ QNLQTCFHFQ  60
   61 AKEIDIIE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [69-521]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPSQFYDLLK TKILNSQNRI FIASLYLGKS ETELVDCISQ ALTKNPKLKV SFLLDGLRGT  60
   61 RELPSACSAT LLSSLVAKYG SERVDCRLYK TPAYHGWKKV LVPKRFNEGL GLQHMKIYGF 120
  121 DNEVILSGAN LSNDYFTNRQ DRYYLFKSRN FSNYYFKLHQ LISSFSYQII KPMVDGSINI 180
  181 IWPDSNPTVE PTKNKRLFLR EASQLLDGFL KSSKQSLPIT AVGQFSTLVY PISQFTPLFP 240
  241 KYNDKSTEKR TILSLLSTIT SNAISWTFTA GYFNILPDIK AKLLATPVAE ANVITASPFA 300
  301 NGFYQSKGVS SNLPGAYLYL SKKFLQDVCR YRQDHAITLR EWQRGVVNKP NGWSYHAKGI 360
  361 WLSARDKNDA NNWKPFITVI GSSNYTRRAY SLDLESNALI ITRDEELRKK MKAELDNLLQ 420
  421 YTKPVTLEDF QSDPERHVGT GVKIATSILG KKL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.221849
Match: 1f0iA_
Description: Phospholipase D
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.42274246180183 bayes_pls_golite062009
catalytic activity 1.29236214516383 bayes_pls_golite062009
phosphoric diester hydrolase activity 1.25148072945538 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.97354820978871 bayes_pls_golite062009
nucleic acid binding 0.566950403258922 bayes_pls_golite062009
protein binding 0.438178121330569 bayes_pls_golite062009
transferase activity 0.417847571627092 bayes_pls_golite062009
kinase activity 0.41582825017763 bayes_pls_golite062009
DNA binding 0.402372477477629 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.398900256450913 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle