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View Structure Prediction Details

Protein: MRPS5
Organism: Saccharomyces cerevisiae
Length: 307 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRPS5.

Description E-value Query
Range
Subject
Range
gi|207347484 - gi|207347484|gb|EDZ73638.1| YBR251Wp-like protein [Saccharomyces cerevisiae AWRI1631]
MRPS5 - Mitochondrial ribosomal protein of the small subunit
gi|151946637 - gi|151946637|gb|EDN64859.1| mitochondrial ribosomal protein [Saccharomyces cerevisiae YJM789]
gi|190408599 - gi|190408599|gb|EDV11864.1| ribosomal protein S5 [Saccharomyces cerevisiae RM11-1a]
RT05_YEAST - 37S ribosomal protein S5, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
3.0E-97 [1..307] [1..307]
gi|2920833 - gi|2920833|gb|AAC04625.1| ribosomal protein S2 [Rattus norvegicus]
5.0E-75 [97..291] [11..215]
RS2_MOUSE - 40S ribosomal protein S2 OS=Mus musculus GN=Rps2 PE=1 SV=3
gi|57718 - gi|57718|emb|CAA40679.1| ribosomal protein S2 [Rattus rattus]
gi|55249864 - gb|AAH86024.1| Unknown (protein for MGC:98099) [Xenopus laevis]
gi|223975107 - gi|223975107|gb|ACN31741.1| unknown [Zea mays]
RS2_RAT - 40S ribosomal protein S2 OS=Rattus norvegicus GN=Rps2 PE=1 SV=1
5.0E-75 [97..291] [54..258]
RS2_BOVIN - (O18789) 40S ribosomal protein S2 (Fragment)
2.0E-74 [97..291] [47..251]
RS2_ICTPU - 40S ribosomal protein S2 OS=Ictalurus punctatus GN=rps2 PE=2 SV=1
4.0E-74 [97..291] [39..243]
RR5_ARATH - 30S ribosomal protein S5, chloroplastic OS=Arabidopsis thaliana GN=rps5 PE=2 SV=1
7.0E-74 [7..302] [25..303]
RS2_CRIGR - 40S ribosomal protein S2 (Fragment) OS=Cricetulus griseus GN=RPS2 PE=2 SV=1
6.0E-73 [105..291] [2..198]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKRQLSTSV RYLQHYDESL LSRYYPESLL KSIKLAQQTI PEDTKFRVSR NVEFAPPYLD  60
   61 DFTKIHPFWD YKPGMPHLHA QEENNNFSIF RWDQVQQPLP GEGNILPPGV SLPNDGGRKS 120
  121 KSADVAAGLH KQTGVD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.390 0.227 mitochondrion a.118.8 TPR-like
View Download 0.346 0.161 RNA binding a.142.1 PTS-regulatory domain, PRD
View Download 0.679 0.022 structural constituent of ribosome a.74.1 Cyclin-like
View Download 0.390 0.017 structural constituent of ribosome a.118.8 TPR-like
View Download 0.328 0.010 structural constituent of ribosome a.96.1 DNA-glycosylase
View Download 0.735 0.007 structural constituent of ribosome d.112.1 Phoshotransferase/anion transport protein
View Download 0.679 0.002 mitochondrion a.74.1 Cyclin-like
View Download 0.346 0.001 structural constituent of ribosome a.142.1 PTS-regulatory domain, PRD
View Download 0.735 0.001 mitochondrion d.112.1 Phoshotransferase/anion transport protein
View Download 0.372 N/A N/A a.74.1 Cyclin-like
View Download 0.313 N/A N/A a.74.1 Cyclin-like
View Download 0.300 N/A N/A c.78.2 Aspartate/glutamate racemase
View Download 0.281 N/A N/A d.112.1 Phoshotransferase/anion transport protein
View Download 0.272 N/A N/A a.66.1 Transducin (alpha subunit), insertion domain
View Download 0.235 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.217 N/A N/A c.10.1 RNI-like

Predicted Domain #2
Region A:
Residues: [137-307]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDYITRKLTM KPLVMKRVSN QTGKGKIASF YALVVVGDKN GMVGLGEGKS REEMSKAIFK  60
   61 AHWDAVRNLK EIPRYENRTI YGDIDFRYHG VKLHLRSAKP GFGLRVNHVI FEICECAGIK 120
  121 DLSGKVYKSR NDMNIAKGTI EAFTKAQKTL DEVALGRGKK LVDVRKVYYS S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 204.9794
Match: 1fjgE_
Description: Ribosomal protein S5, C-terminal domain; Ribosomal S5 protein, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural constituent of ribosome 6.7575603459566 bayes_pls_golite062009
structural molecule activity 6.24187874355454 bayes_pls_golite062009
RNA binding 3.5405508156591 bayes_pls_golite062009
nucleic acid binding 3.06806242310926 bayes_pls_golite062009
binding 2.86619976447436 bayes_pls_golite062009
DNA binding 1.59400162385296 bayes_pls_golite062009
3'-5'-exoribonuclease activity 1.56111033008721 bayes_pls_golite062009
protein binding 1.43319050998069 bayes_pls_golite062009
transcription regulator activity 1.36103792167395 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.35935222635763 bayes_pls_golite062009
exoribonuclease activity 1.31205157616894 bayes_pls_golite062009
3'-5' exonuclease activity 1.10842504252923 bayes_pls_golite062009
double-stranded RNA binding 0.967560318725736 bayes_pls_golite062009
mRNA binding 0.625703291171316 bayes_pls_golite062009
transcription factor activity 0.442070779997034 bayes_pls_golite062009
cytoskeletal protein binding 0.403469167264307 bayes_pls_golite062009
RNA helicase activity 0.222896865667011 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle