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View Structure Prediction Details

Protein: AME1
Organism: Saccharomyces cerevisiae
Length: 324 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AME1.

Description E-value Query
Range
Subject
Range
AME1_YEAST - Central kinetochore subunit AME1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AME1 PE...
AME1 - Essential kinetochore protein associated with microtubules and spindle pole bodies; component of the...
0.0 [1..324] [1..324]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRDTKLAFR LRGSHSRRTD DIDDDVIVFK TPNAVYREEN SPIQSPVQPI LSSPKLANSF  60
   61 EFPITTNNVN AQDRHEHGYQ PLDAEDYPMI DS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [93-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENKSLISESP QNVRNDEDLT TRYNFDDIPI RQLSSSITSV TTIDVLSSLF INLFENDLIP  60
   61 QALKDFNKSD DDQFRKLLYK LDLRLFQTIS DQMTRDLKDI LDINVSNNEL CYQLKQVLAR 120
  121 KEDLNQQIIS VRNEIQELKA GKDWHDLQNE QAKLNDKVKL NKRLNDLTST LLGKYEGDRK 180
  181 IMSQDSEDDS IRDDSNILDI AHFVDLMDPY NGLLKKINKI NENLSNELQP SL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.48
Match: 1qoyA
Description: Hemolysin E (HlyE, ClyA, SheA)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle