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View Structure Prediction Details

Protein: KTR3
Organism: Saccharomyces cerevisiae
Length: 404 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KTR3.

Description E-value Query
Range
Subject
Range
KTR3 - Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of ...
KTR3_YEAST - Probable mannosyltransferase KTR3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KTR3 P...
gi|151946594 - gi|151946594|gb|EDN64816.1| kre2-related protein [Saccharomyces cerevisiae YJM789]
0.0 [1..404] [1..404]
KRE2_CANAL - Glycolipid 2-alpha-mannosyltransferase OS=Candida albicans GN=KRE2 PE=3 SV=1
gi|238880609 - gi|238880609|gb|EEQ44247.1| alpha-1,2 mannosyltransferase KTR1 [Candida albicans WO-1]
MNT1_CANAL - Glycolipid 2-alpha-mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MNT1...
0.0 [83..403] [106..425]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [42..402] [108..455]
OMH2_SCHPO - O-glycoside alpha-1,2-mannosyltransferase homolog 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC ...
SPBC16H5.09c - alpha-1,2-mannosyltransferase
0.0 [24..397] [1..366]

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Predicted Domain #1
Region A:
Residues: [1-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVHHKKKLM PKSALLIRKY QKGIRSSFIG LIIVLSFLFF MSGSRSPEVP IAQGTSVSRV  60
   61 ASKDYLMPFT DKSQGVIHPV DDGKKEKGVM VTLARNSDLW NLVKSIRHVE DRFNNRYHYD 120
  121 WVFLNDQPFS DEFKRVTSAL VSGKAKYGTI PKDHWSIPSW IDTEKFDEKR LAMGKLDIPY 180
  181 GSSVPYRHMC RFQSGFIWRH PLLEEYEWFW RVDTDITLFC DIQYDIFKFL KVNNKKYGFI 240
  241 LSVSEYERTI PTLWETTKKF IKKNPKFLHK NNLMKFISND DGDTYNMCHF WTNFEIGSLD 300
  301 FFRSDAYREY FDYLDSSGGF FYERWGDAPV HSIAASLFLD KSEIHFFDGL GFHHPDFTSC 360
  361 PIEQKIRLQN KCICEPSKDV TWTPDYFCTR KYFSAGNYKL PPGI

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 229.366532
Match: PF01793
Description: Glycolipid 2-alpha-mannosyltransferase

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [75-404]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GVIHPVDDGK KEKGVMVTLA RNSDLWNLVK SIRHVEDRFN NRYHYDWVFL NDQPFSDEFK  60
   61 RVTSALVSGK AKYGTIPKDH WSIPSWIDTE KFDEKRLAMG KLDIPYGSSV PYRHMCRFQS 120
  121 GFIWRHPLLE EYEWFWRVDT DITLFCDIQY DIFKFLKVNN KKYGFILSVS EYERTIPTLW 180
  181 ETTKKFIKKN PKFLHKNNLM KFISNDDGDT YNMCHFWTNF EIGSLDFFRS DAYREYFDYL 240
  241 DSSGGFFYER WGDAPVHSIA ASLFLDKSEI HFFDGLGFHH PDFTSCPIEQ KIRLQNKCIC 300
  301 EPSKDVTWTP DYFCTRKYFS AGNYKLPPGI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 145.0
Match: 1s4nA
Description: Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
alpha-1,2-mannosyltransferase activity 6.0576932895264 bayes_pls_golite062009
mannosyltransferase activity 5.57855076532185 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 4.49413422196176 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 4.37944217610823 bayes_pls_golite062009
UDP-glycosyltransferase activity 4.08451171179562 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 3.4614674054855 bayes_pls_golite062009
transferase activity 3.32517438937547 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 3.19923094610567 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.51696952719873 bayes_pls_golite062009
catalytic activity 1.88676710996045 bayes_pls_golite062009
nucleotidyltransferase activity 1.86990263440735 bayes_pls_golite062009
uridylyltransferase activity 1.27888067902271 bayes_pls_golite062009
binding 0.948692623641759 bayes_pls_golite062009
glucuronosyltransferase activity 0.36353543999278 bayes_pls_golite062009
protein binding 0.124656890356575 bayes_pls_golite062009
UDP-galactosyltransferase activity 0.10185872015123 bayes_pls_golite062009
galactosyltransferase activity 0.0931461042017721 bayes_pls_golite062009
acetylglucosaminyltransferase activity 0.0562130308868509 bayes_pls_golite062009
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 0.0339369954475406 bayes_pls_golite062009
intramolecular oxidoreductase activity 0.0122078907283503 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle