YRC Public Data Repository - Protein Structure Prediction

Protein:	COS111
Organism:	Saccharomyces cerevisiae
Length:	924 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COS111.

Description	E-value	Query Range	Subject Range
CS111_CANGA - F-box protein COS111 OS=Candida glabrata GN=COS111 PE=3 SV=1 CS111_CANGA - F-box protein COS111 OS=Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y...	579.0	[0..7]	[918..1]
CS111_KLULA - F-box protein COS111 OS=Kluyveromyces lactis GN=COS111 PE=3 SV=1 CS111_KLULA - F-box protein COS111 OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / ...	184.0	[0..99]	[918..31]
CS111_DEBHA - F-box protein COS111 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) gi\|50415783, gi\|... - gi\|50415783\|ref\|XP_457497.1\| hypothetical protein DEHA0B12716g [Debaryomyces hansenii CBS767], gi\|49...	108.0	[0..101]	[395..37]
CS111_YARLI - F-box protein COS111 OS=Yarrowia lipolytica GN=COS111 PE=3 SV=1 CS111_YARLI - F-box protein COS111 OS=Yarrowia lipolytica (strain CLIB 122 / E 150) GN=COS111 PE=3 SV=1	98.0	[0..64]	[354..32]
orf19.12346 - orf19.4883 CGDID:CAL0005497 Assembly 19, Contig19-20215 (333907, 331676) CDS, reverse complemented, ... gi\|68465354, gi\|... - gi\|68465354\|ref\|XP_723376.1\| hypothetical protein CaO19.12346 [Candida albicans SC5314], gi\|46445406...	78.0	[0..529]	[576..382]

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Predicted Domain #1

Region A:
Residues: [1-184]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSASRLQNV NIVSNNYSRY GTSVYDKLYH SNGSGSNNAG KNSTTVGKLS SISQKSRSKQ  60
   61 RHGSNCSRSM SQSPLSTFKS PLSNQNQSSA PDDLASIGQR RSDDVTSLDN ETIITMNSRK 120
  121 SRIKKKYKSL ISTSSKKFMN KLYDHGASSD SFSIFSLKTS HSGKHENSRF EKLRKRKYHA 180
  181 WGKF

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [185-297]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADINDLPVEI IAKILSEFEL GRDQKTLVRC LYVSKKFYKA TKIVLYRLPY FTSTYRVAQF  60
   61 VTSLRLHPDN GAYVKVLDLS HLKPGIIGQD SKDSQGLDDD GHSRRHRRRR RRS

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	2.638272
Match:	PF00646
Description:	F-box domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.910	N/A	N/A	a.24.18	Description not found.

Predicted Domain #3

Region A:
Residues: [298-924]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNTSLNLPPA TPTSTISNED DANSGLIKDD ASNGSEVEDL ALAGWRDWRY RNEPLYSSPL  60
   61 LNSFKLKKVV SRSSSITSTS SGNSTGVHST RRQRSNSSVA SITTSIMSSI YNTSHVSLSS 120
  121 TTSNTSNGNI SSGSNLSRVS TAGSLKKASA KSTRSSPQKA KPISDITSSS WFRMRLSSRN 180
  181 RKARTANTIN LKNSKDKSDD DFKVLKHDSG HPSNYRSSTL KFSIEQPFST HHPYANKFLL 240
  241 KYAPYKDLPL GYILHMLNLC PNLVELNLSN LVICTDFKLI NQRSERRRMT SSLLPAVQES 300
  301 SVSAGPEKDL EIVYMTDSGK GYEYYEGLSK KHSRSSSLGT NPSSWIGGQA NWTDYPPPID 360
  361 AQTKTREEHR RNNTLNNKNV VLKKLNPFEI FEMICNRNEE KGGYCSLTKV KMNDIVWCRQ 420
  421 YMVKYFVMRS WRNDLDYKSM ENNSYERHLF SFRDSGLDRN FSWACNAKLH EFVALMVMDH 480
  481 LSNLDDLGLE ELFNIKSEKL YIKNYCCRDP DILEISNLFD IRYGAGSEAD ATSDSNLEAE 540
  541 SLQFRLTILK TEKPTSFWLT KVSKDYVSLV VKLCVDDDID MDKMKVGKPT LRIDSITHNL 600
  601 ISRLKELRRV DLRRNVGENS YYAGSII

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits