YRC Public Data Repository - Protein Structure Prediction

Protein:	YPC1
Organism:	Saccharomyces cerevisiae
Length:	316 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YPC1.

Description	E-value	Query Range	Subject Range
gi\|190407868 - gi\|190407868\|gb\|EDV11133.1\| alkaline ceramidase YDC1 [Saccharomyces cerevisiae RM11-1a] YDC1 - Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroce... gi\|207340550 - gi\|207340550\|gb\|EDZ68866.1\| YPL087Wp-like protein [Saccharomyces cerevisiae AWRI1631] YDC1_YEAST - Alkaline ceramidase YDC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YDC1 PE=1 SV=1 gi\|151942710 - gi\|151942710\|gb\|EDN61056.1\| alkaline dihydroceramidase [Saccharomyces cerevisiae YJM789]	383.0	[0..3]	[308..2]
gi\|62640940, gi\|... - gi\|62640940\|ref\|XP_574497.1\| PREDICTED: similar to Alkaline phytoceramidase (aPHC) (Alkaline ceramid...	330.0	[0..9]	[277..140]
gi\|157071806, gi... - gi\|164427589\|ref\|XP_965356.2\| hypothetical protein NCU02969 [Neurospora crassa OR74A], gi\|157071806\|... gi\|16945385 - gi\|16945385\|emb\|CAD11799.1\| conserved hypothetical protein [Neurospora crassa]	328.0	[0..1]	[297..1]
gi\|49526348, gi\|... - gi\|50289217\|ref\|XP_447039.1\| unnamed protein product [Candida glabrata], gi\|49526348\|emb\|CAG59972.1\|... gi\|49526348 - gi\|49526348\|emb\|CAG59972.1\| unnamed protein product [Candida glabrata]	312.0	[0..4]	[303..3]
ACER3_MOUSE - Alkaline ceramidase 3 OS=Mus musculus GN=Acer3 PE=2 SV=1	304.0	[0..9]	[277..3]
gi\|109108005 - gi\|109108005\|ref\|XP_001088478.1\| PREDICTED: phytoceramidase, alkaline [Macaca mulatta]	301.0	[0..9]	[277..3]
ACER3 - alkaline ceramidase 3 gi\|114639456 - gi\|114639456\|ref\|XP_001175032.1\| PREDICTED: phytoceramidase, alkaline isoform 3 [Pan troglodytes]	300.0	[0..9]	[277..3]
gi\|73987895 - gi\|73987895\|ref\|XP_849760.1\| PREDICTED: similar to Alkaline phytoceramidase (aPHC) (Alkaline ceramid...	290.0	[0..9]	[277..3]
gi\|32419427, gi\|... - gi\|32419427\|ref\|XP_330157.1\| hypothetical protein ( hypothetical protein B7F18.50 [imported] - Neuro... gi\|85117994 - gi\|85117994\|ref\|XP_965356.1\| hypothetical protein	283.0	[0..1]	[252..1]

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Predicted Domain #1

Region A:
Residues: [1-186]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIFRWNYPE SSVPGVWGET TSTIDWCEEN YVVSPYIAEW SNTLTNSVFI LSAIYTTYSA  60
   61 YKNKLEKRFL LIGFGYGLVG VGSWLFHMTL KYRFQLLDEL PMIYAMCIPT WSLVCEAKEA 120
  121 LLNGDNHKKV PLFEQIFIGV IIGLAVTTAS ILYVIYKNVD IHQILFGVQI VVVAATAGSL 180
  181 TYRYVH

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [187-316]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPLAKRNLKA SMALGAILFL SGYISWLLDI HYCSFWVHVR RSILALPLGV LLEPHGWWHI  60
   61 LTGMGIYFYI VSLEHLRVIT LNVSCNYQFI WRWKVFPELI WKGRKPSTRY SLELFGPYVE 120
  121 DQSIEVKKEK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.893	N/A	N/A	c.52.1	Restriction endonuclease-like
View	Download	0.708	N/A	N/A	a.7.1	Spectrin repeat
View	Download	0.708	N/A	N/A	a.7.1	Spectrin repeat
View	Download	0.654	N/A	N/A	a.1.1	Globin-like
View	Download	0.650	N/A	N/A	c.55.4	Translational machinery components
View	Download	0.637	N/A	N/A	d.80.1	Tautomerase/MIF
View	Download	0.637	N/A	N/A	d.80.1	Tautomerase/MIF
View	Download	0.618	N/A	N/A	c.55.4	Translational machinery components

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits