YRC Public Data Repository - Protein Structure Prediction

Protein:	TYR1
Organism:	Saccharomyces cerevisiae
Length:	452 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TYR1.

Description	E-value	Query Range	Subject Range
TYR1_SCHPO - Probable prephenate dehydrogenase [NADP(+)] OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G... tyr1 - prephenate dehydrogenase [NADP+]	473.0	[0..10]	[440..1]
gi\|1749634, gi\|1... - gi\|1749634\|dbj\|BAA13874.1\| unnamed protein product [Schizosaccharomyces pombe], gi\|11359262\|pir\|\|T43...	439.0	[0..41]	[440..2]
gi\|49528922 - gi\|49528922\|emb\|CAG62584.1\| unnamed protein product [Candida glabrata] gi\|50294394, gi\|... - gi\|50294394\|ref\|XP_449608.1\| hypothetical protein CAGL0M06017g [Candida glabrata CBS138], gi\|4952892...	360.0	[0..8]	[447..4]
gi\|49644201, gi\|... - gi\|50310105\|ref\|XP_455066.1\| unnamed protein product [Kluyveromyces lactis], gi\|49644201\|emb\|CAH0015... gi\|49644201 - gi\|49644201\|emb\|CAH00153.1\| KLLA0E24729p [Kluyveromyces lactis]	354.0	[0..4]	[445..5]
gi\|45201315, gi\|... - gi\|45201315\|ref\|NP_986885.1\| AGR219Wp [Ashbya gossypii ATCC 10895], gi\|44986169\|gb\|AAS54709.1\| AGR21... gi\|44986169 - gi\|44986169\|gb\|AAS54709.1\| AGR219Wp [Ashbya gossypii ATCC 10895]	354.0	[0..1]	[440..1]
gi\|49651415, gi\|... - gi\|50556274\|ref\|XP_505545.1\| YALI0F17644p [Yarrowia lipolytica], gi\|49651415\|emb\|CAG78354.1\| unnamed... gi\|49651415 - gi\|49651415\|emb\|CAG78354.1\| YALI0F17644p [Yarrowia lipolytica]	351.0	[0..6]	[441..2]
gi\|159129452 - gi\|159129452\|gb\|EDP54566.1\| prephenate dehydrogenase [Aspergillus fumigatus A1163] gi\|66853016, gi\|... - gi\|71001394\|ref\|XP_755378.1\| prephenate dehydrogenase [Aspergillus fumigatus Af293], gi\|66853016\|gb\|...	348.0	[0..16]	[450..10]
gi\|49658011, gi\|... - gi\|50427457\|ref\|XP_462341.1\| hypothetical protein DEHA0G19591g [Debaryomyces hansenii CBS767], gi\|49... gi\|49658011\|emb\|... - unnamed protein product [Debaryomyces hansenii CBS767]	338.0	[0..2]	[446..4]
gi\|169783482 - gi\|169783482\|ref\|XP_001826203.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83774947 - gi\|83774947\|dbj\|BAE65070.1\| unnamed protein product [Aspergillus oryzae] gi\|238493283, gi... - gi\|238493283\|ref\|XP_002377878.1\| prephenate dehydrogenase [Aspergillus flavus NRRL3357], gi\|22069637...	334.0	[0..16]	[441..10]
gi\|68466390, gi\|... - gi\|68466390\|ref\|XP_722677.1\| hypothetical protein CaO19.4605 [Candida albicans SC5314], gi\|68466097\|... orf19.4605, orf1... - TYR1 CGDID:CAL0003587 Assembly 19, Contig19-10212 (82547, 81228) CDS, reverse complemented, translat...	333.0	[0..14]	[444..13]

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Predicted Domain #1

Region A:
Residues: [1-323]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSEDKIEQW KATKVIGIIG LGDMGLLYAN KFTDAGWGVI CCDREEYYDE LKEKYASAKF  60
   61 ELVKNGHLVS RQSDYIIYSV EASNISKIVA TYGPSSKVGT IVGGQTSCKL PEIEAFEKYL 120
  121 PKDCDIITVH SLHGPKVNTE GQPLVIINHR SQYPESFEFV NSVMACLKSK QVYLTYEEHD 180
  181 KITADTQAVT HAAFLSMGSA WAKIKIYPWT LGVNKWYGGL ENVKVNISLR IYSNKWHVYA 240
  241 GLAITNPSAH QQILQYATSA TELFSLMIDN KEQELTDRLL KAKQFVFGKH TGLLLLDDTI 300
  301 LEKYSLSKSS IGNSNNCKPV PNS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.30103
Match:	2iz0A
Description:	No description for 2iz0A was found.

Predicted Domain #2

Region A:
Residues: [324-452]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HLSLLAIVDS WFQLGIDPYD HMICSTPLFR IFLGVSEYLF LKPGLLEQTI DAAIHDKSFI  60
   61 KDDLEFVISA REWSSVVSFA NFDIYKKQFQ SVQKFFEPML PEANLIGNEM IKTILSHSSD 120
  121 RSAAEKRNT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits