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View Structure Prediction Details

Protein: MAK5
Organism: Saccharomyces cerevisiae
Length: 773 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAK5.

Description E-value Query
Range
Subject
Range
MAK5 - Essential nucleolar protein, putative DEAD-box RNA helicase required for maintenance of M1 dsRNA vir...
MAK5_YEAST - ATP-dependent RNA helicase MAK5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MAK5 PE=...
0.0 [1..773] [1..773]
DDX3_XENLA - Putative ATP-dependent RNA helicase an3 OS=Xenopus laevis GN=an3 PE=2 SV=1
0.0 [1..616] [42..619]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [1..616] [42..619]
gi|13514813, gi|... - gi|2580552|gb|AAC51830.1| dead box, X isoform [Homo sapiens], gi|2580550|gb|AAC51829.1| dead box, X ...
0.0 [12..615] [22..577]
DDX3X_MOUSE - ATP-dependent RNA helicase DDX3X OS=Mus musculus GN=Ddx3x PE=1 SV=3
0.0 [12..615] [22..577]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [12..615] [22..577]

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Predicted Domain #1
Region A:
Residues: [1-163]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKKRAPQKG KTVTKPQEII VDESKLNWKP VDIPDTLDDF GGFYGLEEID GVDVKVVDGK  60
   61 VTFVTKKDSK VLKDSNKEKV GDDQESVENE SGSDSESELL EFKNLDDIKE GELSAASYSS 120
  121 SDEDEQGNIE SSKLTDPSED VDEDVDEDVL KENVFNKDIN IDD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [164-434]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISPVNLPEWT NLAPLSMTIL QSLQNLNFLR PTEIQKKSIP VIMQGVDVMG KASTGSGKTL  60
   61 AYGIPIVEKL ISNFSQKNKK PISLIFTPTR ELAHQVTDHL KKICEPVLAK SQYSILSLTG 120
  121 GLSIQKQQRL LKYDNSGQIV IATPGRFLEL LEKDNTLIKR FSKVNTLILD EADRLLQDGH 180
  181 FDEFEKIIKH LLVERRKNRE NSEGSSKIWQ TLIFSATFSI DLFDKLSSSR QVKDRRFKNN 240
  241 EDELNAVIQH LMSKIHFNSK PVIIDTNPES K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 461.228787
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [435-597]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSSQIKESLI ECPPLERDLY CYYFLTMFPG TTLIFCNAID SVKKLTVYLN NLGIPAFQIH  60
   61 SSMTQKNRLK SLERFKQQSA KQKTINHSNP DSVQLSTVLI ASDVAARGLD IPGVQHVIHY 120
  121 HLPRSTDIYI HRSGRTARAG SEGVSAMICS PQESMGPLRK LRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 461.228787
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [598-720]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLATKNSVST DLNSRSTNRK PIKWQNTVPL LPIETDILSQ LRERSRLAGE LADHEIASNS  60
   61 LRKDDNWLKK AADELGIDVD SDEDDISKSN SDTFLLKNKN KKMQKTINKD KVKAMRATLN 120
  121 ELL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.0
Match: 1d2mA_
Description: Nucleotide excision repair enzyme UvrB
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [721-773]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVPIRKDRRQ KYLTGGLVNL ADNLVKKRGH NSIIGHEKTN ALETLKKKKK RNN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle