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View Structure Prediction Details

Protein: RPG1
Organism: Saccharomyces cerevisiae
Length: 964 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPG1.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
0.0 [9..961] [989..1928]
gi|6683485 - gi|6683485|dbj|BAA89233.1| skeletal myosin heavy chain [Gallus gallus]
0.0 [9..961] [991..1930]
gi|225000798 - gi|225000798|gb|AAI72386.1| Myosin, heavy chain 8, skeletal muscle, perinatal [synthetic construct]
MYH8 - myosin, heavy chain 8, skeletal muscle, perinatal
0.0 [9..961] [990..1929]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
0.0 [9..961] [990..1929]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [9..961] [990..1929]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
0.0 [9..961] [992..1931]

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Predicted Domain #1
Region A:
Residues: [1-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPPFRPEN AIKRADELIS VGEKQAALQS LHDFITARRI RWATPSTVEP VVFKFLEIGV  60
   61 ELKKGKLLKD GLHQYKKLIQ GSTEGLVSVG AVARKFIDLV ESKIASEQTR ADELQKQEID 120
  121 DDLEGGVTPE NLLISVYESD QSVAGFNDEA ITSWLRFT

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.47
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [159-285]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WESYRAVLDL LRNNALLEIT YSGVVKKTMH FCLKYQRKNE FKRLAEMLRQ HLDAANYQQS  60
   61 KSGNNLVDLS DADTLQRYLD QRFQQVDVSV KLELWHEAYR SIEDVFHLMK ISKRAPKPST 120
  121 LANYYEN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.47
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [286-451]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVKVFFVSGD PLLHTTAWKK FYKLYSTNPR ATEEEFKTYS STIFLSAIST QLDEIPSIGY  60
   61 DPHLRMYRLL NLDAKPTRKE MLQSIIEDES IYGKVDEELK ELYDIIEVNF DVDTVKQQLE 120
  121 NLLVKLSSKT YFSQYIAPLR DVIMRRVFVA ASQKFTTVSQ SELYKL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.47
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [452-521]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATLPAPLDLS AWDIEKSLLQ AAVEDYVSIT IDHESAKVTF AKDPFDIFAS TASKEVSEEE  60
   61 NTEPEVQEEK 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.872 0.185 incipient cellular bud site d.58.17 Metal-binding domain
View Download 0.742 0.185 incipient cellular bud site d.58.11 EF-G/eEF-2 domains III and V
View Download 0.742 0.185 incipient cellular bud site d.58.17 Metal-binding domain
View Download 0.666 0.185 incipient cellular bud site d.58.17 Metal-binding domain
View Download 0.620 0.185 incipient cellular bud site d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.567 0.185 incipient cellular bud site d.58.38 Urease metallochaperone UreE, C-terminal domain
View Download 0.565 0.185 incipient cellular bud site d.58.24 CheY-binding domain of CheA
View Download 0.547 0.185 incipient cellular bud site d.58.38 Urease metallochaperone UreE, C-terminal domain
View Download 0.539 0.185 incipient cellular bud site a.6.1 Putative DNA-binding domain
View Download 0.534 0.185 incipient cellular bud site d.58.3 Protease propeptides/inhibitors
View Download 0.528 0.185 incipient cellular bud site d.58.10 Acylphosphatase-like
View Download 0.492 0.185 incipient cellular bud site d.74.2 C-terminal domain of arginine repressor
View Download 0.484 0.185 incipient cellular bud site d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.445 0.185 incipient cellular bud site d.186.1 Head-to-tail joining protein W, gpW
View Download 0.432 0.185 incipient cellular bud site d.9.2 Description not found.
View Download 0.411 0.185 incipient cellular bud site b.40.6 MOP-like
View Download 0.404 0.185 incipient cellular bud site d.52.1 Alpha-lytic protease prodomain
View Download 0.395 0.185 incipient cellular bud site d.58.49 YajQ-like
View Download 0.388 0.185 incipient cellular bud site d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.379 0.185 incipient cellular bud site d.58.25 Killer toxin KP6 alpha-subunit
View Download 0.377 0.185 incipient cellular bud site d.58.5 GlnB-like
View Download 0.375 0.185 incipient cellular bud site d.64.1 eIF1-like
View Download 0.370 0.185 incipient cellular bud site d.58.8 Viral DNA-binding domain
View Download 0.363 0.185 incipient cellular bud site d.58.36 Sulfite reductase, domains 1 and 3
View Download 0.351 0.185 incipient cellular bud site a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.349 0.185 incipient cellular bud site d.58.1 4Fe-4S ferredoxins
View Download 0.342 0.185 incipient cellular bud site d.58.10 Acylphosphatase-like
View Download 0.340 0.185 incipient cellular bud site a.6.1 Putative DNA-binding domain
View Download 0.340 0.185 incipient cellular bud site d.95.1 Glucose permease domain IIB
View Download 0.336 0.185 incipient cellular bud site d.76.1 GYF domain
View Download 0.331 0.185 incipient cellular bud site d.57.1 DNA damage-inducible protein DinI
View Download 0.312 0.185 incipient cellular bud site b.40.4 Nucleic acid-binding proteins
View Download 0.304 0.185 incipient cellular bud site d.37.1 CBS-domain
View Download 0.303 0.185 incipient cellular bud site a.6.1 Putative DNA-binding domain
View Download 0.299 0.185 incipient cellular bud site a.4.1 Homeodomain-like
View Download 0.298 0.185 incipient cellular bud site a.4.5 "Winged helix" DNA-binding domain
View Download 0.296 0.185 incipient cellular bud site a.156.1 S13-like H2TH domain
View Download 0.292 0.185 incipient cellular bud site d.201.1 SRP19
View Download 0.292 0.185 incipient cellular bud site a.4.1 Homeodomain-like
View Download 0.292 0.185 incipient cellular bud site a.64.1 Saposin
View Download 0.288 0.185 incipient cellular bud site a.77.1 DEATH domain
View Download 0.264 0.185 incipient cellular bud site d.58.1 4Fe-4S ferredoxins
View Download 0.261 0.185 incipient cellular bud site a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.249 0.185 incipient cellular bud site d.9.1 Interleukin 8-like chemokines
View Download 0.236 0.185 incipient cellular bud site d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.230 0.185 incipient cellular bud site d.58.7 RNA-binding domain, RBD
View Download 0.225 0.185 incipient cellular bud site d.58.7 RNA-binding domain, RBD
View Download 0.219 0.185 incipient cellular bud site d.74.1 Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
View Download 0.214 0.185 incipient cellular bud site d.58.48 MTH1187-like
View Download 0.212 0.185 incipient cellular bud site a.2.3 Chaperone J-domain
View Download 0.211 0.185 incipient cellular bud site i.1.1 Ribosome and ribosomal fragments
View Download 0.209 0.185 incipient cellular bud site a.144.2 Ribosomal protein L20
View Download 0.209 0.185 incipient cellular bud site d.94.1 HPr-like
View Download 0.208 0.185 incipient cellular bud site d.58.7 RNA-binding domain, RBD
View Download 0.205 0.185 incipient cellular bud site a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.204 0.185 incipient cellular bud site d.19.1 MHC antigen-recognition domain

Predicted Domain #5
Region A:
Residues: [522-610]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EETDEALGPQ ETEDGEEKEE ESDPVIIRNS YIHNKLLELS NVLHDVDSFN NASYMEKVRI  60
   61 ARETLIKKNK DDLEKISKIV DERVKRSQE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [611-964]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKQKHMEHAA LHAEQDAEVR QQRILEEKAA IEAKLEEEAH RRLIEKKKRE FEAIKEREIT  60
   61 KMITEVNAKG HVYIDPNEAK SLDLDTIKQV IIAEVSKNKS ELESRMEYAM KKLDHTERAL 120
  121 RKVELPLLQK EVDKLQETDT ANYEAMKKKI VDAAKAEYEA RMADRKNLVM VYDDYLKFKE 180
  181 HVSGTKESEL AAIRNQKKAE LEAAKKARIE EVRKRRYEEA IARRKEEIAN AERQKRAQEL 240
  241 AEATRKQREI EEAAAKKSTP YSFRAGNREP PSTPSTLPKA TVSPDKAKLD MIAQKQREME 300
  301 EAIEQRLAGR TAGGSSPATP ATPATPATPT PSSGPKKMTM AEKLRAKRLA KGGR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.0
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle