YRC Public Data Repository - Protein Structure Prediction

Protein:	YBR056W
Organism:	Saccharomyces cerevisiae
Length:	501 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YBR056W.

Description	E-value	Query Range	Subject Range
YBR056W - Putative cytoplasmic protein of unknown function gi\|190408781 - gi\|190408781\|gb\|EDV12046.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] YBQ6_YEAST - Uncharacterized glycosyl hydrolase YBR056W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) ...	0.0	[1..501]	[1..501]
exg3 - glucan 1,3-beta-glucosidase Exg3 EXG3_SCHPO - Glucan 1,3-beta-glucosidase 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=exg3 PE=3 SV...	2.0E-81	[35..490]	[3..444]
EXG_KLULA - Glucan 1,3-beta-glucosidase OS=Kluyveromyces lactis GN=KLLA0C05324g PE=3 SV=1 EXG_KLULA - Glucan 1,3-beta-glucosidase OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC ...	4.0E-71	[13..413]	[9..424]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	5.0E-71	[36..413]	[43..434]
EXG_CANAL - Glucan 1,3-beta-glucosidase OS=Candida albicans GN=XOG1 PE=1 SV=3	6.0E-71	[36..413]	[43..434]
EXG2_WICAO - Glucan 1,3-beta-glucosidase 2 OS=Wickerhamomyces anomalus GN=EXG2 PE=3 SV=1	2.0E-70	[12..413]	[6..425]
EXG_SCHOC - Glucan 1,3-beta-glucosidase OS=Schwanniomyces occidentalis PE=3 SV=1	3.0E-69	[12..413]	[6..422]

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Predicted Domain #1

Region A:
Residues: [1-296]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIGSLRNKFE HFKVSEKGGQ NLSTTLPKLP PAKDLDRSTI YKYRYNYGVN LGALFVLEPW  60
   61 IFSKETICTI DGKEYDSEFD AISQQLKKHS SEDVAKMLSD HYKKYIDRID WEWLSKDAHI 120
  121 TALRIPIGYW HVEDGKHLDS LPFAPLRKVY ELAKPWEKLG ELINNAKKMS IGVLIDLHGL 180
  181 PGGANCDSHS GSKSGEAAFF HKEKYMTKVY KDILPAIINT MTLGNENIIG IQVVNEACFD 240
  241 NNPKGQKFYY SEAINTVEKL QPGLPVIISD GWWPQQWADW VKEKHFSEIV VIDSHV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [319-334]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TVNFPHEDAD YTVGEF

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [364-380]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VFSHVASWGW FFWTLQF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	196.68867
Match:	1cz1A_
Description:	Exo-beta-(1,3)-glucanase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [297-318]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YRCFSDSDKS KDANSIIKDL PN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [335-363]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGVLDGQTWN KTSGDRDAIV QKYVQTQAD

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [381-421]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYGDGGEWGL APMMQKGNLP KRPHGDDLQV DKKKIDSIIH E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	196.68867
Match:	1cz1A_
Description:	Exo-beta-(1,3)-glucanase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [422-501]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HEAYWNGKGK NFEHWRFEDG IKTAVDDIIA FRKFDNSLIG RWHSWKSQRR AEYVSAKKDS  60
   61 EFMWEWDQGY QRGLDEFNKY

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits