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View Structure Prediction Details

Protein: SCO1
Organism: Saccharomyces cerevisiae
Length: 295 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SCO1.

Description E-value Query
Range
Subject
Range
gi|207347782 - gi|207347782|gb|EDZ73851.1| YBR024Wp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151946417 - gi|151946417|gb|EDN64639.1| suppressor of cytochrome oxidase deficiency [Saccharomyces cerevisiae YJ...
SCO2 - Protein anchored to the mitochondrial inner membrane, similar to Sco1p and may have a redundant func...
SCO2_YEAST - Protein SCO2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SCO2 PE=1 SV...
219.0 [0..23] [294..27]
gi|3603241 - gi|3603241|gb|AAC35744.1| type II peroxiredoxin 1 [Mus musculus]
217.0 [0..110] [292..6]
gi|632720 - gi|632720|gb|AAB32034.1| TSA=thiol-specific antioxidant [rats, brain, Peptide, 198 aa]
PRDX2_RAT - Peroxiredoxin-2 OS=Rattus norvegicus GN=Prdx2 PE=1 SV=3
216.0 [0..112] [292..8]
PRDX_ASCSU - Peroxiredoxin OS=Ascaris suum PE=2 SV=1
216.0 [0..107] [292..1]
gi|33865747, gi|... - gi|33865747|ref|NP_897306.1| thioredoxin peroxidase [Synechococcus sp. WH 8102], gi|33632917|emb|CAE...
215.0 [0..110] [291..7]
gi|33634943, gi|... - gi|33863026|ref|NP_894586.1| thioredoxin peroxidase [Prochlorococcus marinus str. MIT 9313], gi|3363...
215.0 [0..104] [294..1]

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Predicted Domain #1
Region A:
Residues: [1-109]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKLSRSANL RLVQLPAARL SGNGAKLLTQ RGFFTVTRLW QSNGKKPLSR VPVGGTPIKD  60
   61 NGKVREGSIE FSTGKAIALF LAVGGALSYF FNREKRRLET QKEAEANRG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.338 b.55.1 PH domain-like
View Download 0.316 b.55.1 PH domain-like
View Download 0.312 b.55.1 PH domain-like
View Download 0.293 d.110.3 PYP-like sensor domain (PAS domain)
View Download 0.256 b.55.1 PH domain-like

Predicted Domain #2
Region A:
Residues: [110-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGKPSLGGPF HLEDMYGNEF TEKNLLGKFS IIYFGFSNCP DICPDELDKL GLWLNTLSSK  60
   61 YGITLQPLFI TCDPARDSPA VLKEYLSDFH PSILGLTGTF DEVKNACKKY RVYFSTPPNV 120
  121 KPGQDYLVDH SIFFYLMDPE GQFVDALGRN YDEKTGVDKI VEHVKSYVPA EQRAKQKEAW 180
  181 YSFLFK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.0
Match: 2b7jA
Description: No description for 2b7jA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle