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View Structure Prediction Details

Protein: CHS3
Organism: Saccharomyces cerevisiae
Length: 1165 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CHS3.

Description E-value Query
Range
Subject
Range
gi|172104 - gi|172104|gb|AAA34844.1| chitin synthase [Saccharomyces cerevisiae]
0.0 [1..1165] [1..1165]
CHS4_MAGGR - Chitin synthase 4 (EC 2.4.1.16) (Chitin-UDP acetyl-glucosaminyl transferase 4) (Class-IV chitin synt...
0.0 [13..1151] [60..1184]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [70..1162] [1..1081]
gi|4741879 - gi|4741879|gb|AAD28744.1|AF126146_1 chitin synthase 4; Chs4p [Exophiala dermatitidis]
0.0 [5..1150] [50..1183]
gi|14860982 - gi|14860982|gb|AAK72391.1| chitin synthase 4 [Coccidioides posadasii]
0.0 [10..1150] [48..1184]
gi|6073782 - gi|6073782|emb|CAB41410.1| chitin synthase [Tuber magnatum]
0.0 [21..1150] [61..1181]
CHS3_CANAX - Chitin synthase 3 OS=Candida albicans GN=CHS3 PE=3 SV=1
0.0 [11..1143] [6..1153]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTGLNGDDPD DYYLNLNQDE ESLLRSRHSV GSGAPHRQGS LVRPERSRLN NPDNPHFYYA  60
   61 QKTQEQMNHL DV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [73-543]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSSTGVNPN ATRRSGSLRS KGSVRSKFSG RETDSYLLQD MNTTDKKASV KISDEGVAED  60
   61 EFDKDGDVDN FEESSTQPIN KSIKPLRKET NDTLSFWQMY CYFITFWAPA PILAFCGMPK 120
  121 KERQMAWREK VALISVILYI GAIVAFLTFG FTKTVCSSSK LRLKNNEVST EFVVINGKAY 180
  181 ELDTSSRSGI QDVEVDSDTL YGPWSDAGKD ASFLFQNVNG NCHNLITPKS NSSIPHDDDN 240
  241 NLAWYFPCKL KNQDGSSKPN FTVENYAGWN CHTSKEDRDA FYGLKSKADV YFTWDGIKNS 300
  301 SRNLIVYNGD VLDLDLLDWL EKDDVDYPVV FDDLKTSNLQ GYDLSLVLSN GHERKIARCL 360
  361 SEIIKVGEVD SKTVGCIASD VVLYVSLVFI LSVVIIKFII ACYFRWTVAR KQGAYIVDNK 420
  421 TMDKHTNDIE DWSNNIQTKA PLKEVDPHLR PKKYSKKSLG HKRASTFDLL K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [544-627]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KHSSKMFQFN ESVIDLDTSM SSSLQSSGSY RGMTTMTTQN AWKLSNENKA VHSRNPSTLL  60
   61 PTSSMFWNKA TSSPVPGSSL IQSL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [628-1165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSTIIHPDIV QQPPLDFMPY GFPLIHTICF VTCYSEDEEG LRTTLDSLST TDYPNSHKLL  60
   61 MVVCDGLIKG SGNDKTTPEI ALGMMDDFVT PPDEVKPYSY VAVASGSKRH NMAKIYAGFY 120
  121 KYDDSTIPPE NQQRVPIITI VKCGTPAEQG AAKPGNRGKR DSQIILMSFL EKITFDERMT 180
  181 QLEFQLLKNI WQITGLMADF YETVLMVDAD TKVFPDALTH MVAEMVKDPL IMGLCGETKI 240
  241 ANKAQSWVTA IQVFEYYISH HQAKAFESVF GSVTCLPGCF SMYRIKSPKG SDGYWVPVLA 300
  301 NPDIVERYSD NVTNTLHKKN LLLLGEDRFL SSLMLKTFPK RKQVFVPKAA CKTIAPDKFK 360
  361 VLLSQRRRWI NSTVHNLFEL VLIRDLCGTF CFSMQFVIGI ELIGTMVLPL AICFTIYVII 420
  421 FAIVSKPTPV ITLVLLAIIL GLPGLIVVIT ATRWSYLWWM CVYICALPIW NFVLPSYAYW 480
  481 KFDDFSWGDT RTIAGGNKKA QDENEGEFDH SKIKMRTWRE FEREDILNRK EESDSFVA

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 1000.0
Match: PF03142
Description: Chitin synthase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [642-739]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDFMPYGFPL IHTICFVTCY SEDEEGLRTT LDSLSTTDYP NSHKLLMVVC DGLIKGSGND  60
   61 KTTPEIALGM MDDFVTPPDE VKPYSYVAVA SGSKRHNM

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 5.075721
Match: PF03142.6
Description: No description for PF03142.6 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [740-984]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKIYAGFYKY DDSTIPPENQ QRVPIITIVK CGTPAEQGAA KPGNRGKRDS QIILMSFLEK  60
   61 ITFDERMTQL EFQLLKNIWQ ITGLMADFYE TVLMVDADTK VFPDALTHMV AEMVKDPLIM 120
  121 GLCGETKIAN KAQSWVTAIQ VFEYYISHHQ AKAFESVFGS VTCLPGCFSM YRIKSPKGSD 180
  181 GYWVPVLANP DIVERYSDNV TNTLHKKNLL LLGEDRFLSS LMLKTFPKRK QVFVPKAACK 240
  241 TIAPD

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.0
Match: 1h7lA
Description: Spore coat polysaccharide biosynthesis protein SpsA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity, transferring hexosyl groups 2.23446625487311 bayes_pls_golite062009
UDP-glycosyltransferase activity 1.84596125277114 bayes_pls_golite062009
catalytic activity 1.73979371332125 bayes_pls_golite062009
transferase activity 1.18156663897445 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 0.823843077041128 bayes_pls_golite062009
cytidylyltransferase activity 0.666765511953956 bayes_pls_golite062009
nucleotidyltransferase activity 0.641710647713692 bayes_pls_golite062009
binding 0.61043334112269 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 0.600389101620522 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 0.539883035270389 bayes_pls_golite062009
mannosyltransferase activity 0.505948108814334 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.301396160525425 bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity 0.0309517682490415 bayes_pls_golite062009

Predicted Domain #7
Region A:
Residues: [985-1165]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KFKVLLSQRR RWINSTVHNL FELVLIRDLC GTFCFSMQFV IGIELIGTMV LPLAICFTIY  60
   61 VIIFAIVSKP TPVITLVLLA IILGLPGLIV VITATRWSYL WWMCVYICAL PIWNFVLPSY 120
  121 AYWKFDDFSW GDTRTIAGGN KKAQDENEGE FDHSKIKMRT WREFEREDIL NRKEESDSFV 180
  181 A

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 14.744727
Match: PF03142.6
Description: No description for PF03142.6 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle