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View Structure Prediction Details

Protein: IPP1
Organism: Saccharomyces cerevisiae
Length: 287 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IPP1.

Description E-value Query
Range
Subject
Range
gi|190408817 - gi|190408817|gb|EDV12082.1| inorganic pyrophosphatase [Saccharomyces cerevisiae RM11-1a]
gi|207347796 - gi|207347796|gb|EDZ73861.1| YBR011Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|151946405 - gi|151946405|gb|EDN64627.1| inorganic pyrophosphatase [Saccharomyces cerevisiae YJM789]
IPP1 - Cytoplasmic inorganic pyrophosphatase (PPase), homodimer that catalyzes the rapid exchange of oxygen...
IPYR_YEAST - Inorganic pyrophosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IPP1 PE=1 SV=4
0.0 [1..287] [1..287]

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Predicted Domain #1
Region A:
Residues: [1-287]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTYTTRQIGA KNTLEYKVYI EKDGKPVSAF HDIPLYADKE NNIFNMVVEI PRWTNAKLEI  60
   61 TKEETLNPII QDTKKGKLRF VRNCFPHHGY IHNYGAFPQT WEDPNVSHPE TKAVGDNDPI 120
  121 DVLEIGETIA YTGQVKQVKA LGIMALLDEG ETDWKVIAID INDPLAPKLN DIEDVEKYFP 180
  181 GLLRATNEWF RIYKIPDGKP ENQFAFSGEA KNKKYALDII KETHDSWKQL IAGKSSDSKG 240
  241 IDLTNVTLPD TPTYSKAASD AIPPASPKAD APIDKSIDKW FFISGSV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1722.0
Match: 1yppA_
Description: Inorganic pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
inorganic diphosphatase activity 2.74116819406619 bayes_pls_golite062009
binding 1.77492613217844 bayes_pls_golite062009
catalytic activity 1.33262120571864 bayes_pls_golite062009
protein binding 0.38607803003281 bayes_pls_golite062009
pyrophosphatase activity 0.354425639853757 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.334860448536013 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.333575715544697 bayes_pls_golite062009
hydrolase activity 0.0110854177718558 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle