YRC Public Data Repository - Protein Structure Prediction

Protein:	ERD2
Organism:	Saccharomyces cerevisiae
Length:	219 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERD2.

Description	E-value	Query Range	Subject Range
gi\|73958020 - gi\|73958020\|ref\|XP_850429.1\| PREDICTED: similar to ER lumen protein retaining receptor 2 (KDEL recep... ERD22_MOUSE - ER lumen protein-retaining receptor 2 OS=Mus musculus GN=Kdelr2 PE=1 SV=1 ERD22_BOVIN - ER lumen protein-retaining receptor 2 OS=Bos taurus GN=KDELR2 PE=2 SV=1 ERD22_RAT - ER lumen protein-retaining receptor 2 OS=Rattus norvegicus GN=Kdelr2 PE=2 SV=1 gi\|53734577, gi\|... - gb\|AAH86053.1\| Unknown (protein for MGC:98369) [Xenopus laevis], gb\|AAH83938.1\| Unknown (protein fo... tr\|G1SJ08\|G1SJ08... - pep:novel scaffold:oryCun2:GL018931:94102:114335:1 gene:ENSOCUG00000003101 transcript:ENSOCUT0000000...	4.0E-69	[1..218]	[1..211]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	7.0E-69	[1..218]	[3..213]
ENSCJAT00000030125 - null KDELR2 - KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 ENSPTRT00000034950 - null gi\|109065922 - gi\|109065922\|ref\|XP_001090796.1\| PREDICTED: KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein ret... gi\|90078062 - gi\|90078062\|dbj\|BAE88711.1\| unnamed protein product [Macaca fascicularis] gi\|123999086, gi... - gi\|123999086\|gb\|ABM87127.1\| KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor ...	9.0E-69	[1..218]	[1..211]
ERD2B_ARATH - ER lumen protein-retaining receptor B OS=Arabidopsis thaliana GN=ERD2B PE=1 SV=1	1.0E-67	[1..218]	[1..214]
gi\|195339823, gi... - gi\|195339823\|ref\|XP_002036516.1\| GM18383 [Drosophila sechellia], gi\|194130396\|gb\|EDW52439.1\| GM18383... gi\|220942630, gi... - gi\|220952878\|gb\|ACL88982.1\| KdelR-PA [synthetic construct], gi\|220942630\|gb\|ACL83858.1\| KdelR-PA [sy... KdelR-PB, KdelR-... - The gene KDEL receptor is referred to in FlyBase by the symbol Dmel\KdelR (CG5183, FBgn0022268). It ...	1.0E-67	[1..218]	[1..211]
gi\|190408867 - gi\|190408867\|gb\|EDV12132.1\| HDEL receptor [Saccharomyces cerevisiae RM11-1a] gi\|151946353 - gi\|151946353\|gb\|EDN64575.1\| HDEL receptor [Saccharomyces cerevisiae YJM789] ERD2_YEAST - ER lumen protein-retaining receptor OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERD2... ERD2 - HDEL receptor, an integral membrane protein that binds to the HDEL motif in proteins destined for re...	1.0E-66	[1..219]	[1..219]

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Predicted Domain #1

Region A:
Residues: [1-219]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPFRILGDL SHLTSILILI HNIKTTRYIE GISFKTQTLY ALVFITRYLD LLTFHWVSLY  60
   61 NALMKIFFIV STAYIVVLLQ GSKRTNTIAY NEMLMHDTFK IQHLLIGSAL MSVFFHHKFT 120
  121 FLELAWSFSV WLESVAILPQ LYMLSKGGKT RSLTVHYIFA MGLYRALYIP NWIWRYSTED 180
  181 KKLDKIAFFA GLLQTLLYSD FFYIYYTKVI RGKGFKLPK

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	156.638272
Match:	PF00810
Description:	ER lumen protein retaining receptor

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [119-219]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FTFLELAWSF SVWLESVAIL PQLYMLSKGG KTRSLTVHYI FAMGLYRALY IPNWIWRYST  60
   61 EDKKLDKIAF FAGLLQTLLY SDFFYIYYTK VIRGKGFKLP K

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits