YRC Public Data Repository - Protein Structure Prediction

Protein:	HTB2
Organism:	Saccharomyces cerevisiae
Length:	131 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HTB2.

Description	E-value	Query Range	Subject Range
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-47	[14..129]	[5..122]
gi\|15030326, gi\|... - gi\|15030326\|gb\|AAH11440.1\| LOC665622 protein [Mus musculus], gi\|148700679\|gb\|EDL32626.1\| mCG50238, i...	6.0E-47	[7..128]	[2..125]
gi\|149617766, gi... - gi\|149617828\|ref\|XP_001514740.1\| PREDICTED: similar to histone H2B [Ornithorhynchus anatinus], gi\|14... gi\|55626088 - gi\|55626088\|ref\|XP_518302.1\| PREDICTED: similar to H2B histone family, member F [Pan troglodytes] gi\|167774133 - gi\|167774133\|gb\|ABZ92501.1\| histone cluster 1, H2bo [synthetic construct] HIST1H2BO - histone cluster 1, H2bo	1.0E-46	[7..129]	[2..126]
H2B8_CHICK - Histone H2B 8 OS=Gallus gallus GN=H2B-VIII PE=1 SV=3 gi\|224094548 - gi\|224094548\|ref\|XP_002193403.1\| PREDICTED: similar to histone 1, H2bn (predicted) [Taeniopygia gutt...	2.0E-46	[7..129]	[2..126]

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Predicted Domain #1

Region A:
Residues: [1-131]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSAAEKKPA SKAPAEKKPA AKKTSTSVDG KKRSKVRKET YSSYIYKVLK QTHPDTGISQ  60
   61 KSMSILNSFV NDIFERIATE ASKLAAYNKK STISAREIQT AVRLILPGEL AKHAVSEGTR 120
  121 AVTKYSSSTQ A

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	447.9794
Match:	1id3D_
Description:	Histone H2B
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.73700145395396	bayes_pls_golite062009
DNA binding	1.04127970884713	bayes_pls_golite062009
nucleic acid binding	0.86554830065808	bayes_pls_golite062009
transcription regulator activity	0.57702121108343	bayes_pls_golite062009
protein binding	0.260428734715028	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: