YRC Public Data Repository - Protein Structure Prediction

Protein:	NUP60
Organism:	Saccharomyces cerevisiae
Length:	539 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP60.

Description	E-value	Query Range	Subject Range
NUP60_SCHPO - Nucleoporin nup60 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nup60 PE=1 SV=1 SPCC285.13c - nucleoporin Nup60	369.0	[0..119]	[426..127]
gi\|44984466, gi\|... - gi\|45198515\|ref\|NP_985544.1\| AFL004Cp [Ashbya gossypii ATCC 10895], gi\|44984466\|gb\|AAS53368.1\| AFL00... gi\|44984466 - gi\|44984466\|gb\|AAS53368.1\| AFL004Cp [Ashbya gossypii ATCC 10895]	166.0	[0..7]	[539..9]
gi\|50287925, gi\|... - gi\|50287925\|ref\|XP_446391.1\| unnamed protein product [Candida glabrata], gi\|49525699\|emb\|CAG59318.1\|... gi\|49525699 - gi\|49525699\|emb\|CAG59318.1\| unnamed protein product [Candida glabrata]	139.0	[0..2]	[429..4]
gi\|10863080 - gi\|10863080\|dbj\|BAB16831.1\| YAR002w [Saccharomyces bayanus]	106.0	[0..1]	[62..1]
gi\|49640515, gi\|... - gi\|50302893\|ref\|XP_451384.1\| unnamed protein product [Kluyveromyces lactis], gi\|49640515\|emb\|CAH0297...	94.0	[0..137]	[420..1]
gi\|50549315, gi\|... - gi\|50549315\|ref\|XP_502128.1\| YALI0C22253p [Yarrowia lipolytica], gi\|49647995\|emb\|CAG82448.1\| YALI0C2... gi\|49647995 - gi\|49647995\|emb\|CAG82448.1\| YALI0C22253p [Yarrowia lipolytica]	78.0	[0..119]	[539..124]
gi\|49653845, gi\|... - gi\|50419309\|ref\|XP_458179.1\| hypothetical protein DEHA0C12485g [Debaryomyces hansenii CBS767], gi\|49...	71.0	[0..111]	[426..91]
orf19.2901, orf1... - NUP60 CGDID:CAL0005940 Assembly 19, Contig19-10162 (75659, 77494) CDS, translated using codon table ... gi\|68481029, gi\|... - gi\|68481029\|ref\|XP_715556.1\| hypothetical protein CaO19.2901 [Candida albicans SC5314], gi\|68480918\|...	71.0	[0..101]	[428..129]
unc-89 - status:Partially_confirmed UniProt:O01761 protein_id:AAP68958.1	63.0	[0..151]	[508..1410]

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Predicted Domain #1

Region A:
Residues: [1-69]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRKSLRRAS ATVPSAPYRK QIISNAHNKP SLFSKIKTFF TQKDSARVSP RNNVANKQPR  60
   61 NESFNRRIS

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [70-198]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SMPGGYFHSE ISPDSTVNRS VVVSAVGEAR NDIENKEEEY DETHETNISN AKLANFFSKK  60
   61 GNEPLSEIEI EGVMSLLQKS SKSMITSEGE QKSAEGNNID QSLILKESGS TPISISNAPT 120
  121 FNPKYDTSN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [199-539]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASMNTTLGSI GSRKYSFNYS SLPSPYKTTV YRYSAAKKIP DTYTANTSAQ SIASAKSVRS  60
   61 GVSKSAPSKK ISNTAAALVS LLDENDSKKN NAASELANPY SSYVSQIRKH KRVSPNAAPR 120
  121 QEISEEETTV KPLFQNVPEQ GEEPMKQLNA TKISPSAPSK DSFTKYKPAR SSSLRSNVVV 180
  181 AETSPEKKDG GDKPPSSAFN FSFNTSRNVE PTENAYKSEN APSASSKEFN FTNLQAKPLV 240
  241 GKPKTELTKG DSTPVQPDLS VTPQKSSSKG FVFNSVQKKS RSNLSQENDN EGKHISASID 300
  301 NDFSEEKAEE FDFNVPVVSK QLGNGLVDEN KVEAFKSLYT F

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	11.0
Match:
Description:	No description for 1m2vB was found.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits