YRC Public Data Repository - Protein Structure Prediction

Protein:	FUN12
Organism:	Saccharomyces cerevisiae
Length:	1002 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FUN12.

Description	E-value	Query Range	Subject Range
IF2_ENTCL - Translation initiation factor IF-2 OS=Enterobacter cloacae GN=infB PE=3 SV=1	0.0	[1..959]	[9..891]
IF2_KLEOX - Translation initiation factor IF-2 OS=Klebsiella oxytoca GN=infB PE=3 SV=1	0.0	[1..959]	[9..890]
gi\|15981420, gi\|... - gi\|218930510\|ref\|YP_002348385.1\| translation initiation factor IF-2 [Yersinia pestis CO92], gi\|16123... gi\|25299465 - pir\|\|AI0424 translation initiation factor IF2-2 [imported] - Yersinia pestis (strain CO92) gi\|229687204, gi... - gi\|229899712\|ref\|ZP_04514853.1\| protein chain initiation factor 2, IF2 [Yersinia pestis biovar Orien... gi\|165915325, gi... - gi\|89101686\|ref\|ZP_01174395.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Yersinia pes... gi\|165925657, gi... - gi\|165925657\|ref\|ZP_02221489.1\| translation initiation factor IF-2 [Yersinia pestis biovar Orientali... gi\|229695514, gi... - gi\|229839148\|ref\|ZP_04459307.1\| protein chain initiation factor 2, IF2 [Yersinia pestis biovar Orien... gi\|166010020, gi... - gi\|166010020\|ref\|ZP_02230918.1\| translation initiation factor IF-2 [Yersinia pestis biovar Antiqua s... gi\|167420794, gi... - gi\|167420794\|ref\|ZP_02312547.1\| translation initiation factor IF-2 [Yersinia pestis biovar Orientali... gi\|149288910, gi... - gi\|153997273\|ref\|ZP_02022373.1\| translation initiation factor IF2-2 [Yersinia pestis CA88-4125], gi\|...	0.0	[1..959]	[9..878]
IF2_SALTY - Translation initiation factor IF-2 OS=Salmonella typhimurium GN=infB PE=3 SV=2 IF2_SALTY - Translation initiation factor IF-2 OS=Salmonella typhimurium GN=infB PE=3 SV=2 IF2_SALTY - Translation initiation factor IF-2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) G... IF2_SALPB - Translation initiation factor IF-2 OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=infB P... lcl\|NC_016856.1_... - [gene=infB] [protein=translation initiation factor IF-2] [protein_id=YP_005239464.1] [location=compl... IF2_SALPC - Translation initiation factor IF-2 OS=Salmonella paratyphi C (strain RKS4594) GN=infB PE=3 SV=1 gi\|238910081 - gi\|238910081\|ref\|ZP_04653918.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... IF2_SALDC - Translation initiation factor IF-2 OS=Salmonella dublin (strain CT_02021853) GN=infB PE=3 SV=1 gi\|200388994, gi... - gi\|200388994\|ref\|ZP_03215606.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... gi\|204322405, gi... - gi\|204928083\|ref\|ZP_03219283.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... IF2_SALEP - Translation initiation factor IF-2 OS=Salmonella enteritidis PT4 (strain P125109) GN=infB PE=3 SV=1 IF2_SALHS - Translation initiation factor IF-2 OS=Salmonella heidelberg (strain SL476) GN=infB PE=3 SV=1 gi\|194457721, gi... - gi\|194471357\|ref\|ZP_03077341.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... IF2_SALPB - Translation initiation factor IF-2 OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=infB P... IF2_SALA4 - Translation initiation factor IF-2 OS=Salmonella agona (strain SL483) GN=infB PE=3 SV=1 gi\|197243574, gi... - gi\|197265319\|ref\|ZP_03165393.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... gi\|168262703, gi... - gi\|205348528\|gb\|EDZ35159.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|195633232, gi... - gi\|195633232\|gb\|EDX51646.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|205343413, gi... - gi\|205343413\|gb\|EDZ30177.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... IF2_SALNS - Translation initiation factor IF-2 OS=Salmonella newport (strain SL254) GN=infB PE=3 SV=1 gi\|205323238, gi... - gi\|205323238\|gb\|EDZ11077.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|167990149, gi... - gi\|205331232\|gb\|EDZ17996.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|205333815, gi... - gi\|205333815\|gb\|EDZ20579.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|168243120, gi... - gi\|205337921\|gb\|EDZ24685.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ...	0.0	[1..959]	[9..886]
IF2_SALTY - Translation initiation factor IF-2 OS=Salmonella typhimurium GN=infB PE=3 SV=2 IF2_SALTY - Translation initiation factor IF-2 OS=Salmonella typhimurium GN=infB PE=3 SV=2 IF2_SALTY - Translation initiation factor IF-2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) G... IF2_SALPB - Translation initiation factor IF-2 OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=infB P... lcl\|NC_016856.1_... - [gene=infB] [protein=translation initiation factor IF-2] [protein_id=YP_005239464.1] [location=compl... IF2_SALPC - Translation initiation factor IF-2 OS=Salmonella paratyphi C (strain RKS4594) GN=infB PE=3 SV=1 gi\|238910081 - gi\|238910081\|ref\|ZP_04653918.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... IF2_SALDC - Translation initiation factor IF-2 OS=Salmonella dublin (strain CT_02021853) GN=infB PE=3 SV=1 gi\|200388994, gi... - gi\|200388994\|ref\|ZP_03215606.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... gi\|204322405, gi... - gi\|204928083\|ref\|ZP_03219283.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... IF2_SALEP - Translation initiation factor IF-2 OS=Salmonella enteritidis PT4 (strain P125109) GN=infB PE=3 SV=1 IF2_SALHS - Translation initiation factor IF-2 OS=Salmonella heidelberg (strain SL476) GN=infB PE=3 SV=1 gi\|194457721, gi... - gi\|194471357\|ref\|ZP_03077341.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... IF2_SALPB - Translation initiation factor IF-2 OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=infB P... IF2_SALA4 - Translation initiation factor IF-2 OS=Salmonella agona (strain SL483) GN=infB PE=3 SV=1 gi\|197243574, gi... - gi\|197265319\|ref\|ZP_03165393.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... gi\|168262703, gi... - gi\|205348528\|gb\|EDZ35159.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|195633232, gi... - gi\|195633232\|gb\|EDX51646.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|205343413, gi... - gi\|205343413\|gb\|EDZ30177.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... IF2_SALNS - Translation initiation factor IF-2 OS=Salmonella newport (strain SL254) GN=infB PE=3 SV=1 gi\|205323238, gi... - gi\|205323238\|gb\|EDZ11077.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|167990149, gi... - gi\|205331232\|gb\|EDZ17996.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|205333815, gi... - gi\|205333815\|gb\|EDZ20579.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ... gi\|168243120, gi... - gi\|205337921\|gb\|EDZ24685.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica ...	0.0	[1..959]	[9..886]
IF2_SALTI - Translation initiation factor IF-2 OS=Salmonella typhi GN=infB PE=3 SV=1 gi\|16762051 - gi\|16762051\|ref\|NP_457668.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica... gi\|214000926 - gi\|214000926\|ref\|ZP_03411661.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... IF2_SALTI - Translation initiation factor IF-2 OS=Salmonella typhi GN=infB PE=3 SV=1 gi\|213425434 - gi\|213425434\|ref\|ZP_03358184.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter... gi\|29139174, gi\|... - gi\|29143540\|ref\|NP_806882.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enterica... gi\|213052981 - gi\|213052981\|ref\|ZP_03345859.1\| translation initiation factor IF-2 [Salmonella enterica subsp. enter...	0.0	[1..959]	[9..886]
gi\|188016401, gi... - gi\|188016401\|gb\|EDU54523.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4113... gi\|168754149, gi... - gi\|189358562\|gb\|EDU76981.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4401... gi\|168762134, gi... - gi\|189367599\|gb\|EDU86015.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4501... EG10505 - translation initiation factor IF-2 / Translation initiation factor IF-2 gi\|189361460, gi... - gi\|189361460\|gb\|EDU79879.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4486... gi\|187770883, gi... - gi\|187770883\|gb\|EDU34727.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4196... gi\|189000990, gi... - gi\|189000990\|gb\|EDU69976.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4076... gi\|124525924, gi... - gi\|124525924\|ref\|ZP_01697929.1\| translation initiation factor IF-2 [Escherichia coli B], gi\|12450202... IF2_ECOLI - Translation initiation factor IF-2 - Escherichia coli IF2_ECO5E - Translation initiation factor IF-2 OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=infB PE=3 S... IF2_ECOSE - Translation initiation factor IF-2 OS=Escherichia coli (strain SE11) GN=infB PE=3 SV=1 IF2_ECO8A - Translation initiation factor IF-2 OS=Escherichia coli O8 (strain IAI1) GN=infB PE=3 SV=1 IF2_ECO55 - Translation initiation factor IF-2 OS=Escherichia coli (strain 55989 / EAEC) GN=infB PE=3 SV=1 IF2_ECO7I - Translation initiation factor IF-2 OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=infB PE=3 SV=... IF2_ECOLU - Translation initiation factor IF-2 OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=infB P... gi\|189374161, gi... - gi\|189374161\|gb\|EDU92577.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC869]... gi\|168797769, gi... - gi\|189379615\|gb\|EDU98031.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC508]... IF2_ECODH - Translation initiation factor IF-2 OS=Escherichia coli (strain K12 / DH10B) GN=infB PE=3 SV=1 gi\|194417983, gi... - gi\|194433720\|ref\|ZP_03065995.1\| translation initiation factor IF-2 [Shigella dysenteriae 1012], gi\|1... gi\|195938388 - gi\|195938388\|ref\|ZP_03083770.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC... gi\|208727102, gi... - gi\|208807301\|ref\|ZP_03249638.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC... gi\|208813778, gi... - gi\|208813778\|ref\|ZP_03255107.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC... gi\|208818328, gi... - gi\|208818328\|ref\|ZP_03258648.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC... EG10505 - translation initiation factor IF-2 / Translation initiation factor IF-2 gi\|75239262, gi\|... - gi\|75239262\|ref\|ZP_00723233.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... gi\|193062206, gi... - gi\|75260098\|ref\|ZP_00731376.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... gi\|75513383, gi\|... - gi\|75513383\|ref\|ZP_00735807.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... IF2_ECO57 - Translation initiation factor IF-2 OS=Escherichia coli O157:H7 GN=infB PE=3 SV=1 gi\|89109933, gi\|... - gi\|89109933\|ref\|AP_003713.1\| fused protein chain initiation factor 2, IF2 [Escherichia coli str. K-1... gi\|13363522, gi\|... - gi\|15833303\|ref\|NP_312076.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 str. Sakai... IF2_ECOLC - Translation initiation factor IF-2 OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=inf... IF2_ECOBW - Translation initiation factor IF-2 OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=infB PE=3 S... gi\|251786440, gi... - gi\|251786440\|ref\|YP_003000744.1\| hypothetical protein B21_02986 [Escherichia coli BL21], gi\|24237871... gi\|254289862, gi... - gi\|254289862\|ref\|YP_003055610.1\| translation initiation factor IF-2 [Escherichia coli BL21(DE3)], gi... gi\|226839958, gi... - gi\|254038334\|ref\|ZP_04872392.1\| translation initiation factor IF-2 [Escherichia sp. 1_1_43], gi\|2268... gi\|253975013, gi... - gi\|254163112\|ref\|YP_003046220.1\| translation initiation factor IF-2 [Escherichia coli B str. REL606]... gi\|254594519, gi... - gi\|254795119\|ref\|YP_003079956.1\| protein chain initiation factor 2, IF2 [Escherichia coli O157:H7 st... gi\|83585809, gi\|... - gi\|83585809\|ref\|ZP_00924450.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... IF2_ECO24 - Translation initiation factor IF-2 OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=infB PE=3... IF2_ECOHS - Translation initiation factor IF-2 OS=Escherichia coli O9:H4 (strain HS) GN=infB PE=3 SV=1 gi\|75211119, gi\|... - gi\|75211119\|ref\|ZP_00711232.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... gi\|75228773, gi\|... - gi\|75228773\|ref\|ZP_00715382.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ...	0.0	[1..959]	[9..884]
gi\|227887891, gi... - gi\|227887891\|ref\|ZP_04005696.1\| translation initiation factor IF-2 [Escherichia coli 83972], gi\|2278... gi\|226899119, gi... - gi\|237706079\|ref\|ZP_04536560.1\| translation initiation factor IF-2 [Escherichia sp. 3_2_53FAA], gi\|2... IF2_ECO45 - Translation initiation factor IF-2 OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=infB PE=3 SV=1 IF2_ECO27 - Translation initiation factor IF-2 OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=infB PE=3... sp\|B7UJ63\|IF2_ECO27 - Translation initiation factor IF-2 OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=infB PE=3... IF2_ECOK1 - Translation initiation factor IF-2 OS=Escherichia coli O1:K1 / APEC GN=infB PE=3 SV=1 IF2_ECOL6 - Translation initiation factor IF-2 OS=Escherichia coli O6 GN=infB PE=3 SV=1 IF2_ECOUT - Translation initiation factor IF-2 OS=Escherichia coli (strain UTI89 / UPEC) GN=infB PE=3 SV=1 gi\|75240807, gi\|... - gi\|75240807\|ref\|ZP_00724705.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... IF2_ECOL6 - Translation initiation factor IF-2 OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN... gi\|2597877, gi\|2... - gi\|2597877\|emb\|CAA05541.1\| Initiation factor IF2-alpha [Escherichia coli], gi\|2597873\|emb\|CAA05538.1... IF2_ECOL5 - Translation initiation factor IF-2 OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=infB PE=3 S...	0.0	[1..959]	[9..884]
gi\|15803710, gi\|... - gi\|15803710\|ref\|NP_289744.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 EDL933], g... gi\|25299462 - gi\|25299462\|pir\|\|D85980 protein chain initiation factor IF-2 [imported] - Escherichia coli (strain O...	0.0	[1..959]	[9..884]

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Predicted Domain #1

Region A:
Residues: [1-304]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKSKKNQQ NYWDEEFEED AAQNEEISAT PTPNPESSAG ADDTSREASA SAEGAEAIEG  60
   61 DFMSTLKQSK KKQEKKVIEE KKDGKPILKS KKEKEKEKKE KEKQKKKEQA ARKKAQQQAQ 120
  121 KEKNKELNKQ NVEKAAAEKA AAEKSQKSKG ESDKPSASAK KPAKKVPAGL AALRRQLELK 180
  181 KQLEEQEKLE REEEERLEKE EEERLANEEK MKEEAKAAKK EKEKAKREKR KAEGKLLTRK 240
  241 QKEEKKLLER RRAALLSSGN VKVAGLAKKD GEENKPKKVV YSKKKKRTTQ ENASEAIKSD 300
  301 SKKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.09691
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [305-385]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEVVPDDELK ESEDVLIDDW ENLALGDDDE EGTNEETQES TASHENEDQN QGEEEEEGEE  60
   61 EEEEEEERAH VHEVAKSTPA A

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.475	d.58.1	4Fe-4S ferredoxins
View	Download	0.310	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.620	a.7.7	BAG domain
View	Download	0.623	a.7.7	BAG domain
View	Download	0.414	a.64.1	Saposin
View	Download	0.378	d.49.1	Signal recognition particle alu RNA binding heterodimer, SRP9/14
View	Download	0.449	a.130.1	Chorismate mutase II
View	Download	0.483	a.46.1	Methionine synthase domain
View	Download	0.692	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain
View	Download	0.692	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain
View	Download	0.620	a.7.7	BAG domain
View	Download	0.524	a.112.1	Description not found.
View	Download	0.483	a.46.1	Methionine synthase domain
View	Download	0.408	a.46.1	Methionine synthase domain
View	Download	0.390	a.60.2	RuvA domain 2-like
View	Download	0.378	a.3.1	Cytochrome c
View	Download	0.378	d.49.1	Signal recognition particle alu RNA binding heterodimer, SRP9/14
View	Download	0.353	a.4.6	C-terminal effector domain of the bipartite response regulators
View	Download	0.332	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.323	a.3.1	Cytochrome c
View	Download	0.310	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.306	a.23.1	HSC20 (HSCB), C-terminal oligomerisation domain
View	Download	0.292	d.50.1	dsRNA-binding domain-like
View	Download	0.282	a.39.1	EF-hand
View	Download	0.265	a.60.1	SAM/Pointed domain
View	Download	0.255	a.3.1	Cytochrome c
View	Download	0.251	a.29.2	Bromodomain
View	Download	0.245	a.61.1	Retroviral matrix proteins
View	Download	0.236	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.232	d.192.1	YlxR-like
View	Download	0.227	a.1.1	Globin-like
View	Download	0.215	f.36.1	Neurotransmitter-gated ion-channel pransmembrane pore
View	Download	0.212	a.4.1	Homeodomain-like
View	Download	0.210	a.77.1	DEATH domain
View	Download	0.207	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View	Download	0.206	a.48.1	N-terminal domain of cbl (N-cbl)
View	Download	0.204	a.3.1	Cytochrome c
View	Download	0.202	a.4.9	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3

Predicted Domain #3

Region A:
Residues: [386-623]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPAATPTPSS ASPNKKDLRS PICCILGHVD TGKTKLLDKI RQTNVQGGEA GGITQQIGAT  60
   61 YFPIDAIKAK TKVMAEYEKQ TFDVPGLLVI DTPGHESFSN LRSRGSSLCN IAILVIDIMH 120
  121 GLEQQTIESI KLLRDRKAPF VVALNKIDRL YDWKAIPNNS FRDSFAKQSR AVQEEFQSRY 180
  181 SKIQLELAEQ GLNSELYFQN KNMSKYVSIV PTSAVTGEGV PDLLWLLLEL TQKRMSKQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1064.0
Match:	1g7sA_
Description:	Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
translation initiation factor activity	4.55032413246022	bayes_pls_golite062009
catalytic activity	1.37148167194523	bayes_pls_golite062009
nucleic acid binding	0.993540749660144	bayes_pls_golite062009
binding	0.923764328759134	bayes_pls_golite062009
translation regulator activity	0.92120490618839	bayes_pls_golite062009
translation factor activity, nucleic acid binding	0.91253097238055	bayes_pls_golite062009
purine ribonucleotide binding	0.16063798469602	bayes_pls_golite062009
ribonucleotide binding	0.16015711008109	bayes_pls_golite062009
protein binding	0.153255883232138	bayes_pls_golite062009
purine nucleotide binding	0.146890053953086	bayes_pls_golite062009
nucleotide binding	0.136564780426908	bayes_pls_golite062009
DNA binding	0.128213991729785	bayes_pls_golite062009
transcription regulator activity	0.125640198783258	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [624-741]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMYLSHVEAT ILEVKVVEGF GTTIDVILSN GYLREGDRIV LCGMNGPIVT NIRALLTPQP  60
   61 LRELRLKSEY VHHKEVKAAL GVKIAANDLE KAVSGSRLLV VGPEDDEDEL MDDVMDDL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1064.0
Match:	1g7sA_
Description:	Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [742-854]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGLLDSVDTT GKGVVVQAST LGSLEALLDF LKDMKIPVMS IGLGPVYKRD VMKASTMLEK  60
   61 APEYAVMLCF DVKVDKEAEQ YAEQEGIKIF NADVIYHLFD SFTAYQEKLL EER

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1064.0
Match:	1g7sA_
Description:	Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted Domain #6

Region A:
Residues: [855-1002]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKDFLDYAIF PCVLQTLQII NKRGPMIIGV DVLEGTLRVG TPICAVKTDP TTKERQTLIL  60
   61 GKVISLEINH QPVQEVKKGQ TAAGVAVRLE DPSGQQPIWG RHVDENDTLY SLVSRRSIDT 120
  121 LKDKAFRDQV ARSDWLLLKK LKVVFGIE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1064.0
Match:	1g7sA_
Description:	Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

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Predicted functions: