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View Structure Prediction Details

Protein: COX3
Organism: Saccharomyces cerevisiae
Length: 269 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX3.

Description E-value Query
Range
Subject
Range
gi|25006061, gi|... - gi|25057822|ref|NP_740055.1| cytochrome c oxidase subunit III [Carangoides armatus], gi|25006061|dbj...
337.0 [0..7] [268..1]

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Predicted Domain #1
Region A:
Residues: [1-269]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTHLERSRHQ QHPFHMVMPS PWPIVVSFAL LSLALSTALT MHGYIGNMNM VYLALFVLLT  60
   61 SSILWFRDIV AEATYLGDHT MAVRKGINLG FLMFVLSEVL IFAGLFWAYF HSAMSPDVTL 120
  121 GACWPPVGIE AVQPTELPLL NTIILLSSGA TVTYSHHALI AGNRNKALSG LLITFWLIVI 180
  181 FVTCQYIEYT NAAFTISDGV YGSVFYAGTG LHFLHMVMLA AMLGVNYWRM RNYHLTAGHH 240
  241 VGYETTIIYT HVLDVIWLFL YVVFYWWGV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 88.522879
Match: 1v54C
Description: Bovine heart cytochrome c oxidase at the fully oxidized state
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
heme-copper terminal oxidase activity 13.9244114195067 bayes_pls_golite062009
cytochrome-c oxidase activity 13.505405811205 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 13.505405811205 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 13.505405811205 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 7.31668050843038 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 7.16121862598394 bayes_pls_golite062009
oxidoreductase activity 7.1216347731521 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 6.54437171773305 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 6.34326776776315 bayes_pls_golite062009
cation transmembrane transporter activity 6.27309510235419 bayes_pls_golite062009
ion transmembrane transporter activity 6.06282622264651 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.62906931991048 bayes_pls_golite062009
substrate-specific transporter activity 5.4089893828569 bayes_pls_golite062009
catalytic activity 1.98531969314183 bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity 1.6935397585603 bayes_pls_golite062009
electron carrier activity 1.34577598409766 bayes_pls_golite062009
transporter activity 0.35324929562432 bayes_pls_golite062009
transmembrane transporter activity 0.33851611347292 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor 0.0615932880841081 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle