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View Structure Prediction Details

Protein: COX2
Organism: Saccharomyces cerevisiae
Length: 251 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX2.

Description E-value Query
Range
Subject
Range
COX2_VIGUN - Cytochrome c oxidase subunit 2, mitochondrial (Fragment) OS=Vigna unguiculata GN=COX2 PE=2 SV=2
352.0 [0..9] [251..130]

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Predicted Domain #1
Region A:
Residues: [1-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDLLRLQLT TFIMNDVPTP YACYFQDSAT PNQEGILELH DNIMFYLLVI LGLVSWMLYT  60
   61 IVMTYSKNPI AYKYIKHGQT IEVIWTIFPA VILLIIAFPS FILLYLCDEV ISPAMTIKAI 120
  121 GYQWYWKYEY SDFINDSGET VEFESYVIPD ELLEEGQLRL LDTDTSMVVP VDTHIRFVVT 180
  181 AADVIHDFAI PSLGIKVDAT PGRLNQVSAL IQREGVFYGA CSELCGTGHA NMPIKIEAVS 240
  241 LPKFLEWLNE Q

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 64.522879
Match: 1occB
Description: Cytochrome c oxidase; Mitochondrial cytochrome c oxidase, subunit II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
heme-copper terminal oxidase activity 11.9675111703706 bayes_pls_golite062009
cytochrome-c oxidase activity 11.8880744416502 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 11.8880744416502 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 11.8880744416502 bayes_pls_golite062009
oxidoreductase activity 5.65538295246639 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 5.58345655724775 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 5.42917542404103 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 5.29537051871239 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 5.16682116741947 bayes_pls_golite062009
cation transmembrane transporter activity 4.89891856458607 bayes_pls_golite062009
ion transmembrane transporter activity 4.69052551796432 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.2605366734397 bayes_pls_golite062009
substrate-specific transporter activity 4.04391929184076 bayes_pls_golite062009
electron carrier activity 1.92012405624998 bayes_pls_golite062009
binding 0.910231434235845 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.50970361410839 bayes_pls_golite062009
kinase activity 0.487072060813572 bayes_pls_golite062009
protein kinase activity 0.436639038220637 bayes_pls_golite062009
catalytic activity 0.363071622766357 bayes_pls_golite062009
oxidoreduction-driven active transmembrane transporter activity 0.35835230050467 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.325944931150435 bayes_pls_golite062009
protein binding 0.31459442397123 bayes_pls_golite062009
ephrin receptor binding 0.0573211102210707 bayes_pls_golite062009
receptor binding 0.02789117638033 bayes_pls_golite062009

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