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View Structure Prediction Details

Protein: COB
Organism: Saccharomyces cerevisiae
Length: 385 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COB.

Description E-value Query
Range
Subject
Range
gi|12407248 - gi|12407248|dbj|BAB21395.1| cytochrome b [Rhyacichthys aspro]
664.0 [0..2] [384..3]

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Predicted Domain #1
Region A:
Residues: [1-385]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFRKSNVYL SLVNSYIIDS PQPSSINYWW NMGSLLGLCL VIQIVTGIFM AMHYSSNIEL  60
   61 AFSSVEHIMR DVHNGYILRY LHANGASFFF MVMFMHMAKG LYYGSYRSPR VTLWNVGVII 120
  121 FILTIATAFL GYCCVYGQMS HWGATVITNL FSAIPFVGND IVSWLWGGFS VSNPTIQRFF 180
  181 ALHYLVPFII AAMVIMHLMA LHIHGSSNPL GITGNLDRIP MHSYFIFKDL VTVFLFMLIL 240
  241 ALFVFYSPNT LGHPDNYIPG NPLVTPASIV PEWYLLPFYA ILRSIPDKLL GVITMFAAIL 300
  301 VLLVLPFTDR SVVRGNTFKV LSKFFFFIFV FNFVLLGQIG ACHVEVPYVL MGQIATFIYF 360
  361 AYFLIIVPVI STIENVLFYI GRVNK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 148.0
Match: 1ezvC
Description: Mitochondrial cytochrome b subunit, C-terminal domain; Mitochondrial cytochrome b subunit, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor 12.6027406026517 bayes_pls_golite062009
ubiquinol-cytochrome-c reductase activity 12.6027406026517 bayes_pls_golite062009
electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity 9.40961255429881 bayes_pls_golite062009
oxidoreductase activity, acting on diphenols and related substances as donors 9.20388916419937 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 7.91754205622571 bayes_pls_golite062009
oxidoreductase activity 6.47658304679899 bayes_pls_golite062009
electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity 6.28608054530718 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 6.2092870783393 bayes_pls_golite062009
cation transmembrane transporter activity 5.7873765619132 bayes_pls_golite062009
ion transmembrane transporter activity 5.68072183887254 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 5.3015608578326 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.25342386319285 bayes_pls_golite062009
NADH dehydrogenase activity 4.56441771839315 bayes_pls_golite062009
electron carrier activity 4.44921672214173 bayes_pls_golite062009
formate dehydrogenase activity 3.83149707063563 bayes_pls_golite062009
transporter activity 3.45764306673522 bayes_pls_golite062009
substrate-specific transporter activity 3.38637995472629 bayes_pls_golite062009
transmembrane transporter activity 3.37175230596465 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 2.22476140193744 bayes_pls_golite062009
catalytic activity 1.19342057724506 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 1.03512868485178 bayes_pls_golite062009
binding 0.774901332897627 bayes_pls_golite062009
protein binding 0.404482007264961 bayes_pls_golite062009
nucleic acid binding 0.158842209858127 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle