YRC Public Data Repository - Protein Structure Prediction

Protein:	DEOC_TREDE
Organism:	Treponema denticola
Length:	216 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DEOC_TREDE.

Description	E-value	Query Range	Subject Range
DEOC_PYRKO - Probable deoxyribose-phosphate aldolase OS=Pyrococcus kodakaraensis GN=deoC PE=3 SV=1 DEOC_THEKO - Deoxyribose-phosphate aldolase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)...	215.0	[0..2]	[215..5]
DEOC_CARHZ - Deoxyribose-phosphate aldolase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 ...	210.0	[0..2]	[215..6]
gi\|56421034, gi\|... - gi\|56421034\|ref\|YP_148352.1\| deoxyribose-phosphate aldolase [Geobacillus kaustophilus HTA426], gi\|56...	207.0	[0..1]	[215..53]
DEOC_THETN - Deoxyribose-phosphate aldolase OS=Thermoanaerobacter tengcongensis GN=deoC PE=3 SV=1 DEOC_CALS4 - Deoxyribose-phosphate aldolase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 152...	202.0	[0..1]	[214..9]
DEOC_MYCHO - Deoxyribose-phosphate aldolase OS=Mycoplasma hominis GN=deoC PE=3 SV=1	202.0	[0..2]	[202..3]
DEOC_CALS8 - Deoxyribose-phosphate aldolase OS=Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903...	200.0	[0..2]	[213..5]
DEOC_THEMA - Deoxyribose-phosphate aldolase OS=Thermotoga maritima GN=deoC PE=1 SV=1 DEOC_THEMA - Deoxyribose-phosphate aldolase OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 100...	199.0	[0..2]	[215..30]
gi\|27574193, gi\|... - gi\|27574193\|pdb\|1O0Y\|B Chain B, Crystal Structure Of Deoxyribose-Phosphate Aldolase (Tm1559) From Th...	199.0	[0..2]	[215..42]
gi\|80977211, gi\|... - gi\|81096736\|ref\|ZP_00875069.1\| Deoxyribose-phosphate aldolase [Streptococcus suis 89/1591], gi\|80977...	198.0	[0..1]	[215..1]
DEOC1_MESFL - Deoxyribose-phosphate aldolase 1 OS=Mesoplasma florum (strain ATCC 33453 / NBRC 100688 / NCTC 11704 ... DEOC1_MESFL - Deoxyribose-phosphate aldolase 1 OS=Mesoplasma florum GN=deoC1 PE=3 SV=1	198.0	[0..1]	[216..1]

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Predicted Domain #1

Region A:
Residues: [1-216]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELNKYIDHT LLKPTASEKD IIKICNEAKE YHFASVCVNP CNVSLVRKEL KGSDVKVCSV  60
   61 ISFPFGASST EVKVEEAKKA IEAGAEEIDM VINVGKLLEG DLEYTQNEVS AITKACHEKN 120
  121 VLLKVIVETC YLEEKNIADI CAIIEKAGAD FIKTSTGYGS RGASVEDIKL FKKYLKKDTK 180
  181 IKASGGVRTR EDAETYIGLG CSRIGASSGI AIVTGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.221849
Match:	1o0yA
Description:	Deoxyribose-phosphate aldolase DeoC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	3.04075198078553	bayes_pls_golite062009
deoxyribose-phosphate aldolase activity	2.53712494800381	bayes_pls_golite062009
transaldolase activity	0.657551083859431	bayes_pls_golite062009
lyase activity	0.437176828950096	bayes_pls_golite062009
aldehyde-lyase activity	0.41660515357045	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.270307871677629	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: