YRC Public Data Repository - Protein Structure Prediction

Protein:	OMH2_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	372 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OMH2_SCHPO.

Description	E-value	Query Range	Subject Range
KTR3 - Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of ... KTR3_YEAST - Probable mannosyltransferase KTR3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KTR3 P... gi\|151946594 - gi\|151946594\|gb\|EDN64816.1\| kre2-related protein [Saccharomyces cerevisiae YJM789]	536.0	[0..1]	[370..24]
KRE2_CANAL - Glycolipid 2-alpha-mannosyltransferase OS=Candida albicans GN=KRE2 PE=3 SV=1 gi\|238880609 - gi\|238880609\|gb\|EEQ44247.1\| alpha-1,2 mannosyltransferase KTR1 [Candida albicans WO-1] MNT1_CANAL - Glycolipid 2-alpha-mannosyltransferase 1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) GN=MNT1...	525.0	[0..63]	[366..110]
gi\|49654834 - gi\|49654834\|emb\|CAG87338.1\| DEHA2D15708p [Debaryomyces hansenii] gi\|49654834, gi\|... - gi\|50421243\|ref\|XP_459167.1\| hypothetical protein DEHA0D17105g [Debaryomyces hansenii CBS767], gi\|49...	523.0	[0..52]	[371..87]
gi\|59802977 - gi\|59802977\|gb\|AAX07685.1\| glycolipid 2-alpha-mannosyltransferase-like protein [Magnaporthe grisea] gi\|145009235, gi... - gi\|39948507\|ref\|XP_363108.1\| conserved hypothetical protein [Magnaporthe grisea 70-15], gb\|EAA51170....	517.0	[0..55]	[371..109]
gi\|44985528 - gi\|44985528\|gb\|AAS54224.1\| AGL267Cp [Ashbya gossypii ATCC 10895] gi\|45200830, gi\|... - gi\|45200830\|ref\|NP_986400.1\| AGL267Cp [Ashbya gossypii ATCC 10895], gi\|44985528\|gb\|AAS54224.1\| AGL26...	515.0	[0..55]	[370..101]
gi\|66851206, gi\|... - gi\|70997663\|ref\|XP_753570.1\| alpha-1,2-mannosyltransferase (Kre2) [Aspergillus fumigatus Af293], gi\|... gi\|159126699 - gi\|159126699\|gb\|EDP51815.1\| alpha-1,2-mannosyltransferase (Kre2), putative [Aspergillus fumigatus A1...	512.0	[0..5]	[371..9]
gi\|32411831, gi\|... - gi\|32411831\|ref\|XP_326396.1\| hypothetical protein [Neurospora crassa], gi\|28923849\|gb\|EAA33012.1\| al... gi\|85106793 - gi\|85106793\|ref\|XP_962248.1\| alpha-1,2 mannosyltransferase KTR1 [Neurospora crassa OR74A]	510.0	[0..55]	[371..107]

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Predicted Domain #1

Region A:
Residues: [1-372]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRISRLLIRV LLGFVILFIT YILFPSIPKA LVNTLNVYKL EERLNYYNDR LLDGNLKSKE  60
   61 LENATFVTLA RNADLYDLIE TINIYENRFN SKHNYPWVFL NDEPFTRTFE VVMSRLTSGP 120
  121 TYFGVVNSSE WDIPKWIDMD IAHSNWNRLS REGVLYGGMK SYRQMCRYFS GFFWRHPLLD 180
  181 PYKYYWRVEP STKLLCEVNK DPFRQLRLLN KTYGFVITLF EIGQTVPSLW NSTLEFIEKY 240
  241 PETLAKNNLW EWISDDNGKK FSHCHFWSNF EIADLDFFRS DSYRKYFDFL DKKGGFFYER 300
  301 WGDAPVHSIA LSLFLDRNKL HYFDEIGYSH APLLHCPRKG RCFCKPEEID LSSNSSCIAR 360
  361 FINLTNEDYD EL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	136.0
Match:	1s4nA
Description:	Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
alpha-1,2-mannosyltransferase activity	6.0576932895264	bayes_pls_golite062009
mannosyltransferase activity	5.57855076532185	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	4.49413422196176	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	4.37944217610823	bayes_pls_golite062009
UDP-glycosyltransferase activity	4.08451171179562	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	3.4614674054855	bayes_pls_golite062009
transferase activity	3.32517438937547	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	3.19923094610567	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.51696952719873	bayes_pls_golite062009
catalytic activity	1.88676710996045	bayes_pls_golite062009
nucleotidyltransferase activity	1.86990263440735	bayes_pls_golite062009
uridylyltransferase activity	1.27888067902271	bayes_pls_golite062009
binding	0.948692623641759	bayes_pls_golite062009
glucuronosyltransferase activity	0.36353543999278	bayes_pls_golite062009
protein binding	0.124656890356575	bayes_pls_golite062009
UDP-galactosyltransferase activity	0.10185872015123	bayes_pls_golite062009
galactosyltransferase activity	0.0931461042017721	bayes_pls_golite062009
acetylglucosaminyltransferase activity	0.0562130308868509	bayes_pls_golite062009
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	0.0339369954475406	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.0122078907283503	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: