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View Structure Prediction Details

Protein: gi|60814946
Organism: synthetic construct
Length: 276 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|60814946.

Description E-value Query
Range
Subject
Range
gi|60826960 - gi|60826960|gb|AAX36778.1| COX11-like cytochrome c oxidase assembly protein [synthetic construct]
0.0 [1..276] [1..276]
gi|123999817, gi... - gi|123999817|gb|ABM87417.1| COX11 homolog, cytochrome c oxidase assembly protein (yeast) [synthetic ...
gi|21264410, gi|... - sp|Q9Y6N1|COXZ_HUMAN Cytochrome c oxidase assembly protein COX11, mitochondrial precursor, gi|135434...
0.0 [1..276] [1..276]
gi|109114390 - gi|109114390|ref|XP_001102862.1| PREDICTED: similar to COX11 homolog [Macaca mulatta]
0.0 [1..276] [1..276]
gi|55730891 - gi|55730891|emb|CAH92164.1| hypothetical protein [Pongo abelii]
gi|55730891|emb|... - hypothetical protein [Pongo pygmaeus]
0.0 [1..276] [1..277]
gi|109488791, gi... - ref|XP_213433.2| similar to COX11 homolog; cytochrome c oxidase subunit 11; cytochrome c oxidase ass...
0.0 [1..276] [1..275]
COX11_MOUSE - Cytochrome c oxidase assembly protein COX11, mitochondrial OS=Mus musculus GN=Cox11 PE=1 SV=1
0.0 [1..276] [1..275]
gi|73966488 - gi|73966488|ref|XP_866470.1| PREDICTED: similar to COX11 homolog isoform 2 [Canis familiaris]
0.0 [1..276] [1..276]

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Predicted Domain #1
Region A:
Residues: [1-82]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGLWRPGWR CVPFCGWRWI HPGSPTRAAE RVEPFLRPEW SGTGGAERGL RWLGTWKRCS  60
   61 LRARHPALQP PRRPKSSNPF TR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [83-276]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQEEERRRQN KTTLTYVAAV AVGMLGASYA AVPLYRLYCQ TTGLGGSAVA GHASDKIENM  60
   61 VPVKDRIIKI SFNADVHASL QWNFRPQQTE IYVVPGETAL AFYRAKNPTD KPVIGISTYN 120
  121 IVPFEAGQYF NKIQCFCFEE QRLNPQEEVD MPVFFYIDPE FAEDPRMIKV DLITLSYTFF 180
  181 EAKEGHKLPV PGYN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.69897
Match: 1so9A
Description: Solution Structure of apoCox11, 30 structures
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
structural molecule activity 4.47117060684776 bayes_pls_golite062009
cytochrome-c oxidase activity 1.63692440621606 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 1.63692440621606 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 1.63692440621606 bayes_pls_golite062009
heme-copper terminal oxidase activity 1.45348828463274 bayes_pls_golite062009
binding 1.26238051646126 bayes_pls_golite062009
oxidoreductase activity 1.03472539732492 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.401392171756694 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.312235007946628 bayes_pls_golite062009
copper ion binding 0.19463795974816 bayes_pls_golite062009
catalytic activity 0.176396048613815 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.0231690475060109 bayes_pls_golite062009
cation transmembrane transporter activity 0.0170756391184381 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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