YRC Public Data Repository - Protein Structure Prediction

Protein:	RPIA_SALCH
Organism:	Salmonella enterica subsp. enterica serovar Choleraesuis str. SC-B67
Length:	219 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPIA_SALCH.

Description	E-value	Query Range	Subject Range
gi\|24114166, gi\|... - ref\|NP_708676.1\| ribose-5-phosphate isomerase, constitutive [Shigella flexneri 2a str. 301], gb\|AAN... gi\|26109738, gi\|... - gi\|26249330\|ref\|NP_755370.1\| ribose-5-phosphate isomerase A [Escherichia coli CFT073], gi\|26109738\|g... gi\|91212293, gi\|... - gi\|91212293\|ref\|YP_542279.1\| ribose-5-phosphate isomerase A [Escherichia coli UTI89], gi\|91073867\|gb... gi\|226899478, gi... - gi\|237706438\|ref\|ZP_04536919.1\| ribose-5-phosphate isomerase A [Escherichia sp. 3_2_53FAA], gi\|22689... gi\|226839585, gi... - gi\|254037961\|ref\|ZP_04872019.1\| ribose-5-phosphate isomerase A [Escherichia sp. 1_1_43], gi\|22683958...	2.0E-74	[1..219]	[25..243]
RPIA_NITEU - Ribose-5-phosphate isomerase A OS=Nitrosomonas europaea GN=rpiA PE=3 SV=1 RPIA_NITEU - Ribose-5-phosphate isomerase A OS=Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298) GN=rpiA PE=...	3.0E-74	[1..218]	[1..218]
gi\|83587691 - gi\|83587691\|ref\|ZP_00926318.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli 101-1] gi\|42943 - gi\|42943\|emb\|CAA47309.1\| unnamed protein product [Escherichia coli] gi\|75178806 - gi\|75178806\|ref\|ZP_00698842.1\| COG0120: Ribose 5-phosphate isomerase [Shigella boydii BS512] gi\|75187629 - gi\|75187629\|ref\|ZP_00700896.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli E24377A] RPIA_ECOK1 - Ribose-5-phosphate isomerase A OS=Escherichia coli O1:K1 / APEC GN=rpiA PE=3 SV=1 gi\|75196865 - gi\|75196865\|ref\|ZP_00706935.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli HS] gi\|124526181, gi... - gi\|124526181\|ref\|ZP_01698186.1\| ribose 5-phosphate isomerase [Escherichia coli B], gi\|124502285\|gb\|E... gi\|227888463, gi... - gi\|227888463\|ref\|ZP_04006268.1\| ribose-5-phosphate isomerase A [Escherichia coli 83972], gi\|22783473... gi\|75212472 - gi\|75212472\|ref\|ZP_00712496.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli B171] gi\|75228581 - gi\|75228581\|ref\|ZP_00715210.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli B7A] gi\|75239518 - gi\|75239518\|ref\|ZP_00723489.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli E110019] gi\|75258513 - gi\|75258513\|ref\|ZP_00729935.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli E22]	1.0E-73	[1..219]	[13..231]
gi\|208808380, gi... - gi\|208808380\|ref\|ZP_03250717.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4206... gi\|195936532 - gi\|195936532\|ref\|ZP_03081914.1\| ribose-5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4024... gi\|194424196, gi... - gi\|194436714\|ref\|ZP_03068814.1\| ribose 5-phosphate isomerase A [Escherichia coli 101-1], gi\|19442419... gi\|194415547, gi... - gi\|194426239\|ref\|ZP_03058794.1\| ribose 5-phosphate isomerase A [Escherichia coli B171], gi\|194415547... RPIA_ECOSE - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain SE11) GN=rpiA PE=3 SV=1 RPIA_ECO5E - Ribose-5-phosphate isomerase A OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=rpiA PE=3 SV=1 gi\|208819067, gi... - gi\|208819067\|ref\|ZP_03259387.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4042... gi\|208813802, gi... - gi\|208813802\|ref\|ZP_03255131.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4045... RPIA_ECOSM - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=rpiA PE=3 SV=1 RPIA_ECODH - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain K12 / DH10B) GN=rpiA PE=3 SV=1 gi\|189379720, gi... - gi\|189379720\|gb\|EDU98136.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC508], gi... gi\|189373917, gi... - gi\|189373917\|gb\|EDU92333.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC869], gi... gi\|193067384, gi... - gi\|193067384\|ref\|ZP_03048352.1\| ribose 5-phosphate isomerase A [Escherichia coli E110019], gi\|192959... gi\|193063514, gi... - gi\|193063514\|ref\|ZP_03044603.1\| ribose 5-phosphate isomerase A [Escherichia coli E22], gi\|192930791\|... gi\|191168214, gi... - gi\|191168214\|ref\|ZP_03030009.1\| ribose 5-phosphate isomerase A [Escherichia coli B7A], gi\|190901756\|... RPIA_SHIB3 - Ribose-5-phosphate isomerase A OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=rpiA P... RPIA_ECOLI - Ribose-5-phosphate isomerase A (EC 5.3.1.6) (Phosphoriboisomerase A) (PRI) - Escherichia coli RPIA_ECO45 - Ribose-5-phosphate isomerase A OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=rpiA PE=3 SV=1 RPIA_ECO8A - Ribose-5-phosphate isomerase A OS=Escherichia coli O8 (strain IAI1) GN=rpiA PE=3 SV=1 gi\|217319466, gi... - gi\|217327099\|ref\|ZP_03443182.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. TW1458... RPIA_ECO27 - Ribose-5-phosphate isomerase A OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=rpiA PE=3 SV=... RPIA_ECOLU - Ribose-5-phosphate isomerase A OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=rpiA PE=3 ... RPIA_ECO7I - Ribose-5-phosphate isomerase A OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=rpiA PE=3 SV=1 RPIA_ECO55 - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain 55989 / EAEC) GN=rpiA PE=3 SV=1 RPIA_ECO81 - Ribose-5-phosphate isomerase A OS=Escherichia coli O81 (strain ED1a) GN=rpiA PE=3 SV=1 EG11443 - ribose 5-phosphate isomerase, constitutive / Ribose-5-phosphate isomerase A, alkali-inducible sp\|B7UHW1\|RPIA_ECO27 - Ribose-5-phosphate isomerase A OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=rpiA PE=3 SV=... RPIA_ECOLC - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=rpiA PE... gi\|168753856, gi... - gi\|189358712\|gb\|EDU77131.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4401], g... gi\|168747603, gi... - gi\|188017814\|gb\|EDU55936.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4113], g... gi\|189000540, gi... - gi\|189000540\|gb\|EDU69526.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4076], g... gi\|168773456, gi... - gi\|187770763\|gb\|EDU34607.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4196], g... gi\|168766911, gi... - gi\|189363891\|gb\|EDU82310.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4486], g... gi\|242378444, gi... - gi\|251786171\|ref\|YP_003000475.1\| hypothetical protein B21_02708 [Escherichia coli BL21], gi\|24237844... gi\|189369231, gi... - gi\|189369231\|gb\|EDU87647.1\| ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4501], g... RPIA_ECOBW - Ribose-5-phosphate isomerase A OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=rpiA PE=3 SV=1 gi\|254162825, gi... - gi\|254162825\|ref\|YP_003045933.1\| ribose-5-phosphate isomerase A [Escherichia coli B str. REL606], gi... gi\|253978892, gi... - gi\|254289585\|ref\|YP_003055333.1\| ribose-5-phosphate isomerase A [Escherichia coli BL21(DE3)], gi\|253... gi\|254594263, gi... - gi\|254794863\|ref\|YP_003079700.1\| ribose 5-phosphate isomerase, constitutive [Escherichia coli O157:H... RPIA_ECOL6 - Ribose-5-phosphate isomerase A OS=Escherichia coli O6 GN=rpiA PE=3 SV=1 gi\|56383751, gi\|... - gi\|56480200\|ref\|NP_708676.2\| ribose-5-phosphate isomerase A [Shigella flexneri 2a str. 301], gi\|5638... RPIA_SHIBS - Ribose-5-phosphate isomerase A OS=Shigella boydii serotype 4 (strain Sb227) GN=rpiA PE=3 SV=1 gi\|85675725, gi\|... - gi\|89109692\|ref\|AP_003472.1\| ribosephosphate isomerase, constitutive [Escherichia coli str. K-12 sub... gi\|13363257, gi\|... - gi\|15833039\|ref\|NP_311812.1\| ribose-5-phosphate isomerase A [Escherichia coli O157:H7 str. Sakai], g... RPIA_SHIF8 - Ribose-5-phosphate isomerase A OS=Shigella flexneri serotype 5b (strain 8401) GN=rpiA PE=3 SV=1 RPIA_SHISS - Ribose-5-phosphate isomerase A OS=Shigella sonnei (strain Ss046) GN=rpiA PE=3 SV=1 RPIA_SHIDS - Ribose-5-phosphate isomerase A OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=rpiA PE=3 SV=1 RPIA_ECOL6 - Ribose-5-phosphate isomerase A OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=rpi... RPIA_SHIFL - Ribose-5-phosphate isomerase A OS=Shigella flexneri GN=rpiA PE=3 SV=1 gi\|30064224, gi\|... - gi\|30064224\|ref\|NP_838395.1\| ribose-5-phosphate isomerase A [Shigella flexneri 2a str. 2457T], gi\|30... RPIA_ECO57 - Ribose-5-phosphate isomerase A OS=Escherichia coli O157:H7 GN=rpiA PE=3 SV=1 EG11443 - ribose 5-phosphate isomerase, constitutive / Ribose-5-phosphate isomerase A, alkali-inducible gi\|12517444, gi\|... - gi\|15803449\|ref\|NP_289482.1\| ribose-5-phosphate isomerase A [Escherichia coli O157:H7 EDL933], gi\|12... RPIA_ECOHS - Ribose-5-phosphate isomerase A OS=Escherichia coli O9:H4 (strain HS) GN=rpiA PE=3 SV=1 RPIA_ECO24 - Ribose-5-phosphate isomerase A OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=rpiA PE=3 SV=...	1.0E-73	[1..219]	[1..219]
gi\|114308819, gi... - gi\|71550684\|ref\|ZP_00670776.1\| Ribose 5-phosphate isomerase [Nitrosomonas eutropha C71], gi\|71484115...	2.0E-73	[1..218]	[23..240]
gi\|75241290 - gi\|75241290\|ref\|ZP_00725152.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli F11]	2.0E-73	[1..219]	[13..231]
gi\|94426307, gi\|... - gi\|94501489\|ref\|ZP_01308007.1\| ribose 5-phosphate isomerase A [Oceanobacter sp. RED65], gi\|94426307\|...	6.0E-73	[1..218]	[1..222]
RPIA_ERWCT - Ribose-5-phosphate isomerase A OS=Erwinia carotovora subsp. atroseptica GN=rpiA PE=3 SV=1 RPIA_PECAS - Ribose-5-phosphate isomerase A OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN=r...	7.0E-73	[1..219]	[1..219]
gi\|75515302 - gi\|75515302\|ref\|ZP_00737486.1\| COG0120: Ribose 5-phosphate isomerase [Escherichia coli 53638]	7.0E-73	[1..219]	[13..231]
RPIA_EDWIC - Ribose-5-phosphate isomerase A OS=Edwardsiella ictaluri GN=rpiA PE=3 SV=1 RPIA_EDWI9 - Ribose-5-phosphate isomerase A OS=Edwardsiella ictaluri (strain 93-146) GN=rpiA PE=3 SV=1	7.0E-73	[1..218]	[1..218]

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Predicted Domain #1

Region A:
Residues: [1-219]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQDELKKAV GWAALQYVQP GTIVGVGTGS TAAHFIDALG TMKGQIEGAV SSSDASTEKL  60
   61 KGLGIHVFDL NEVDSLGIYV DGADEINGHM QMIKGGGAAL TREKIIASVA EKFICIADAS 120
  121 KQVDILGKFP LPVEVIPMAR SAVARQLVKL GGRPEYRQNV VTDNGNVILD VYGMEILDPI 180
  181 ALENAINAIP GVVTVGLFAN RGADVALIGT PDGVKTIVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.09691
Match:	1ks2A
Description:	D-ribose-5-phosphate isomerase (RpiA), catalytic domain; D-ribose-5-phosphate isomerase (RpiA), lid domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribose-5-phosphate isomerase activity	2.23318567990318	bayes_pls_golite062009
6-phosphogluconolactonase activity	1.97756803122763	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.61058174487002	bayes_pls_golite062009
catalytic activity	0.424959044318554	bayes_pls_golite062009
nucleic acid binding	0.281224782944976	bayes_pls_golite062009
binding	0.228090098582514	bayes_pls_golite062009
glucosamine-6-phosphate deaminase activity	0.111185777194415	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting aldoses and ketoses	0.075853172283603	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: