YRC Public Data Repository - Protein Structure Prediction

Protein:	HIS1_YERP3
Organism:	Yersinia pseudotuberculosis IP 31758
Length:	299 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS1_YERP3.

Description	E-value	Query Range	Subject Range
gi\|168986284, gi... - gi\|168986343\|dbj\|BAG11882.1\| ATP phosphoribosyltransferase [Escherichia coli O55:H7], gi\|168986284\|d... HIS1_ECOHS - ATP phosphoribosyltransferase OS=Escherichia coli O9:H4 (strain HS) GN=hisG PE=3 SV=1 gi\|168986400 - gi\|168986400\|dbj\|BAG11938.1\| ATP phosphoribosyltransferase [Escherichia coli O55:H6] HIS1_ECO24 - ATP phosphoribosyltransferase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=hisG PE=3 SV=1 HIS1_ECO27 - ATP phosphoribosyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=hisG PE=3 SV=1 HIS1_ECO8A - ATP phosphoribosyltransferase OS=Escherichia coli O8 (strain IAI1) GN=hisG PE=3 SV=1 gi\|237704476, gi... - gi\|237704476\|ref\|ZP_04534957.1\| ATP phosphoribosyltransferase [Escherichia sp. 3_2_53FAA], gi\|226900... HIS1_ECO45 - ATP phosphoribosyltransferase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=hisG PE=3 SV=1 HIS1_ECO55 - ATP phosphoribosyltransferase OS=Escherichia coli (strain 55989 / EAEC) GN=hisG PE=3 SV=1 gi\|194428767, gi... - gi\|194428767\|ref\|ZP_03061303.1\| ATP phosphoribosyltransferase [Escherichia coli B171], gi\|194413214\|... gi\|194431506, gi... - gi\|194431506\|ref\|ZP_03063798.1\| ATP phosphoribosyltransferase [Shigella dysenteriae 1012], gi\|194420... gi\|194424870, gi... - gi\|194436142\|ref\|ZP_03068244.1\| ATP phosphoribosyltransferase [Escherichia coli 101-1], gi\|194424870... HIS1_ECOBW - ATP phosphoribosyltransferase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=hisG PE=3 SV=1 HIS1_ECOSE - ATP phosphoribosyltransferase OS=Escherichia coli (strain SE11) GN=hisG PE=3 SV=1 HIS1_SHISS - ATP phosphoribosyltransferase OS=Shigella sonnei (strain Ss046) GN=hisG PE=3 SV=1 HIS1_ECOL6 - ATP phosphoribosyltransferase OS=Escherichia coli O6 GN=hisG PE=3 SV=1 HIS1_ECOLI - ATP phosphoribosyltransferase (EC 2.4.2.17) (ATP-PRTase) (ATP-PRT) - Escherichia coli EG10449 - ATP phosphoribosyltransferase / ATP-phosphoribosyltransferase HIS1_ECOLC - ATP phosphoribosyltransferase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=hisG PE=... sp\|B7UT56\|HIS1_ECO27 - ATP phosphoribosyltransferase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=hisG PE=3 SV=1 HIS1_SHIB3 - ATP phosphoribosyltransferase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=hisG PE... gi\|190909654, gi... - gi\|191170138\|ref\|ZP_03031692.1\| ATP phosphoribosyltransferase [Escherichia coli F11], gi\|190909654\|g... gi\|193062818, gi... - gi\|193062818\|ref\|ZP_03043911.1\| ATP phosphoribosyltransferase [Escherichia coli E22], gi\|192931461\|g... gi\|192955107, gi... - gi\|193071570\|ref\|ZP_03052478.1\| ATP phosphoribosyltransferase [Escherichia coli E110019], gi\|1929551... gi\|124530718, gi... - gi\|124530718\|ref\|ZP_01701275.1\| ATP phosphoribosyltransferase [Escherichia coli B], gi\|124499036\|gb\|... HIS1_ECOK1 - ATP phosphoribosyltransferase OS=Escherichia coli O1:K1 / APEC GN=hisG PE=3 SV=1 HIS1_ECODH - ATP phosphoribosyltransferase OS=Escherichia coli (strain K12 / DH10B) GN=hisG PE=3 SV=1 HIS1_ECOSM - ATP phosphoribosyltransferase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=hisG PE=3 SV=1 gi\|1736697, gi\|8... - gi\|89108840\|ref\|AP_002620.1\| ATP phosphoribosyltransferase [Escherichia coli str. K-12 substr. W3110... HIS1_ECOL6 - ATP phosphoribosyltransferase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=hisG... HIS1_ECOUT - ATP phosphoribosyltransferase OS=Escherichia coli (strain UTI89 / UPEC) GN=hisG PE=3 SV=1 EG10449 - ATP phosphoribosyltransferase / ATP-phosphoribosyltransferase HIS1_ECOL5 - ATP phosphoribosyltransferase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=hisG PE=3 SV=1	0.0	[1..299]	[1..299]
HIS1_SHIDS - ATP phosphoribosyltransferase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=hisG PE=3 SV=1	0.0	[1..299]	[1..299]
HIS1_SHIBS - ATP phosphoribosyltransferase OS=Shigella boydii serotype 4 (strain Sb227) GN=hisG PE=3 SV=1 HIS1_ECO7I - ATP phosphoribosyltransferase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=hisG PE=3 SV=1	0.0	[1..299]	[1..299]
gi\|56480021, gi\|... - gi\|56480021\|ref\|NP_707914.2\| ATP phosphoribosyltransferase [Shigella flexneri 2a str. 301], gi\|56383... HIS1_SHIFL - ATP phosphoribosyltransferase OS=Shigella flexneri GN=hisG PE=3 SV=2 HIS1_SHIF8 - ATP phosphoribosyltransferase OS=Shigella flexneri serotype 5b (strain 8401) GN=hisG PE=3 SV=1 gi\|30063469, gi\|... - gi\|30063469\|ref\|NP_837640.1\| ATP phosphoribosyltransferase [Shigella flexneri 2a str. 2457T], gi\|300...	0.0	[1..299]	[1..299]
gi\|168751655, gi... - gi\|188014356\|gb\|EDU52478.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4113], gi... gi\|254793801, gi... - gi\|254793801\|ref\|YP_003078638.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. TW1435... gi\|15832074, gi\|... - gi\|15832074\|ref\|NP_310847.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. Sakai], gi... gi\|217329547, gi... - gi\|217329547\|ref\|ZP_03445626.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. TW14588... HIS1_ECO57 - ATP phosphoribosyltransferase OS=Escherichia coli O157:H7 GN=hisG PE=3 SV=1 gi\|208729034, gi... - gi\|208809233\|ref\|ZP_03251570.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4206]... gi\|208817178, gi... - gi\|208817178\|ref\|ZP_03258270.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4045]... gi\|208818490, gi... - gi\|208818490\|ref\|ZP_03258810.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4042]... HIS1_ECO5E - ATP phosphoribosyltransferase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=hisG PE=3 SV=1 gi\|189000125, gi... - gi\|189000125\|gb\|EDU69111.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4076], gi... gi\|189371603, gi... - gi\|189371603\|gb\|EDU90019.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC869], gi\|... gi\|189378472, gi... - gi\|189378472\|gb\|EDU96888.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC508], gi\|... gi\|195939357 - gi\|195939357\|ref\|ZP_03084739.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4024] gi\|12516200, gi\|... - gi\|15802498\|ref\|NP_288524.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 EDL933], gi\|125... gi\|168757561, gi... - gi\|189355459\|gb\|EDU73878.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4401], gi... gi\|25286968, gi\|... - pir\|\|B85827 ATP phosphoribosyltransferase [imported] - Escherichia coli (strain O157:H7, substrain ... gi\|168764104, gi... - gi\|189365829\|gb\|EDU84245.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501], gi... gi\|189361200, gi... - gi\|189361200\|gb\|EDU79619.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4486], gi... gi\|168775535, gi... - gi\|187768985\|gb\|EDU32829.1\| ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4196], gi...	0.0	[1..299]	[1..299]
gi\|41708 - gi\|41708\|emb\|CAA31811.1\| unnamed protein product [Escherichia coli]	0.0	[1..299]	[1..299]
gi\|238795757, gi... - gi\|77962459\|ref\|ZP_00826279.1\| COG0040: ATP phosphoribosyltransferase [Yersinia mollaretii ATCC 4396...	0.0	[1..299]	[1..299]
HIS1_SALCH - ATP phosphoribosyltransferase OS=Salmonella choleraesuis GN=hisG PE=3 SV=1 HIS1_SALTY - ATP phosphoribosyltransferase OS=Salmonella typhimurium GN=hisG PE=1 SV=1 HIS1_SALCH - ATP phosphoribosyltransferase OS=Salmonella choleraesuis GN=hisG PE=3 SV=1 gi\|1045578, gi\|1... - gi\|1045581\|gb\|AAA80247.1\| ATP phosphoribosyltransferase, gi\|1045578\|gb\|AAA80244.1\| ATP phosphoribosy... gi\|1045587, gi\|1... - gi\|1045587\|gb\|AAA80252.1\| ATP phosphoribosyltransferase, gi\|1045584\|gb\|AAA80249.1\| ATP phosphoribosy... gi\|1045593, gi\|1... - gi\|1045593\|gb\|AAA80257.1\| ATP phosphoribosyltransferase, gi\|1045590\|gb\|AAA80254.1\| ATP phosphoribosy... gi\|1045599, gi\|1... - gi\|1045599\|gb\|AAA80262.1\| ATP phosphoribosyltransferase, gi\|1045596\|gb\|AAA80259.1\| ATP phosphoribosy... HIS1_SALCH - ATP phosphoribosyltransferase OS=Salmonella choleraesuis (strain SC-B67) GN=hisG PE=3 SV=1 HIS1_SALPC - ATP phosphoribosyltransferase OS=Salmonella paratyphi C (strain RKS4594) GN=hisG PE=3 SV=1 lcl\|NC_016856.1_... - [gene=hisG] [protein=ATP phosphoribosyltransferase] [protein_id=YP_005238106.2] [location=2201167..2... HIS1_SALTY - ATP phosphoribosyltransferase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=his... gi\|197265915, gi... - gi\|197265915\|ref\|ZP_03165989.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... HIS1_SALHS - ATP phosphoribosyltransferase OS=Salmonella heidelberg (strain SL476) GN=hisG PE=3 SV=1 gi\|168466274, gi... - gi\|195631210\|gb\|EDX49770.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica serov... gi\|205338573, gi... - gi\|205338573\|gb\|EDZ25337.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica serov... HIS1_SALTY - ATP phosphoribosyltransferase OS=Salmonella typhimurium GN=hisG PE=1 SV=1 gi\|205330536, gi... - gi\|205330536\|gb\|EDZ17300.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica serov...	0.0	[1..299]	[1..299]
gi\|238761358, gi... - gi\|238761358\|ref\|ZP_04622334.1\| ATP phosphoribosyltransferase [Yersinia kristensenii ATCC 33638], gi... gi\|238722050, gi... - gi\|77975874\|ref\|ZP_00831408.1\| COG0040: ATP phosphoribosyltransferase [Yersinia frederiksenii ATCC 3... HIS1_YERE8 - ATP phosphoribosyltransferase OS=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 1317...	0.0	[1..299]	[1..299]
HIS1_SALPA - ATP phosphoribosyltransferase OS=Salmonella paratyphi A GN=hisG PE=3 SV=1 HIS1_SALTI - ATP phosphoribosyltransferase OS=Salmonella typhi GN=hisG PE=3 SV=1 HIS1_SALTI - ATP phosphoribosyltransferase OS=Salmonella typhi GN=hisG PE=3 SV=1 gi\|213648080 - gi\|213648080\|ref\|ZP_03378133.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... HIS1_SALPA - ATP phosphoribosyltransferase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=hisG PE=3 SV=... gi\|29141302, gi\|... - gi\|29141302\|ref\|NP_804644.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|16761002 - gi\|16761002\|ref\|NP_456619.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica sero... gi\|213161015 - gi\|213161015\|ref\|ZP_03346725.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... gi\|213419233 - gi\|213419233\|ref\|ZP_03352299.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... gi\|213425570 - gi\|213425570\|ref\|ZP_03358320.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... gi\|213613119 - gi\|213613119\|ref\|ZP_03370945.1\| ATP phosphoribosyltransferase [Salmonella enterica subsp. enterica s... HIS1_SALPK - ATP phosphoribosyltransferase OS=Salmonella paratyphi A (strain AKU_12601) GN=hisG PE=3 SV=1 HIS1_SALDC - ATP phosphoribosyltransferase OS=Salmonella dublin (strain CT_02021853) GN=hisG PE=3 SV=1	0.0	[1..299]	[1..299]

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Predicted Domain #1

Region A:
Residues: [1-299]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDKTRLRIA MQKSGRLSDE SQELLSRCGI KINLQQQRLI AFAENMPIDI LRVRDDDIPG  60
   61 LVMDGVVDLG IIGENVLEEE LLNRRAQGDD PRYFTLRRLD FGGCRLSLAA PLDAEYTGPQ 120
  121 CLQDTRIATS YPHILKQYLD KQGVRFKSCL LNGSVEVAPR AGLADAICDL VSTGATLEAN 180
  181 GLREVEVIYR SKACLIQRDG EMSVDKQQLI DRLMTRIQGV IQARESKYIM MHAPSERLDE 240
  241 IITLLPGAER PTILPLAGDK SRVAMHMVSS ETLFWETMEK LKALGASSIL VLPIEKMME

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	118.0
Match:	1h3dA
Description:	STRUCTURE OF THE E.COLI ATP-PHOSPHORIBOSYLTRANSFERASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ATP phosphoribosyltransferase activity	1.91045033958508	bayes_pls_golite062009
nucleic acid binding	0.411352163551675	bayes_pls_golite062009
transcription factor activity	0.388220094901111	bayes_pls_golite062009
DNA binding	0.381460145340259	bayes_pls_golite062009
transcription regulator activity	0.264041862712904	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	0.136083454159139	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: