YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|75814053, gi\|...
Organism:	Vibrio cholerae V52
Length:	173 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|75814053, gi|....

Description	E-value	Query Range	Subject Range
RUVC_VIBVY - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio vulnificus (strain YJ016) GN=ruvC PE=3 SV=1	246.0	[0..1]	[173..1]
RUVC_VIBVU - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio vulnificus GN=ruvC PE=3 SV=1 RUVC_VIBVU - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio vulnificus (strain CMCP6) GN=ruvC PE=3 SV=1	246.0	[0..1]	[173..1]
RUVC_VIBPA - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio parahaemolyticus GN=ruvC PE=3 SV=1 RUVC_VIBPA - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD... gi\|153839739, gi... - gi\|153839739\|ref\|ZP_01992406.1\| crossover junction endodeoxyribonuclease RuvC [Vibrio parahaemolytic...	242.0	[0..1]	[173..1]
RUVC_VIBTL - Crossover junction endodeoxyribonuclease RuvC OS=Vibrio tasmaniensis (strain LGP32) GN=ruvC PE=3 SV=... gi\|85835744, gi\|... - gi\|86146481\|ref\|ZP_01064804.1\| Holliday junction resolvase [Vibrio sp. MED222], gi\|85835744\|gb\|EAQ53...	237.0	[0..1]	[173..1]
gi\|84377066, gi\|... - gi\|84388517\|ref\|ZP_00991064.1\| Holliday junction resolvase [Vibrio splendidus 12B01], gi\|84377066\|gb...	236.0	[0..1]	[173..1]
RUVC_SHEFN - Crossover junction endodeoxyribonuclease RuvC OS=Shewanella frigidimarina (strain NCIMB 400) GN=ruvC...	231.0	[0..1]	[173..1]
gi\|76811143, gi\|... - gi\|76811143\|ref\|YP_334776.1\| Holliday junction resolvase [Burkholderia pseudomallei 1710b], gi\|76580...	227.0	[0..3]	[173..97]
RUVC_METFK - Crossover junction endodeoxyribonuclease RuvC OS=Methylobacillus flagellatus (strain KT / ATCC 51484...	227.0	[0..3]	[172..4]
gi\|83652274, gi\|... - gi\|83718449\|ref\|YP_441796.1\| crossover junction endodeoxyribonuclease RuvC [Burkholderia thailandens...	226.0	[0..3]	[173..134]
RUVC_NITEC - Crossover junction endodeoxyribonuclease RuvC OS=Nitrosomonas eutropha (strain C91) GN=ruvC PE=3 SV=...	226.0	[0..3]	[170..9]

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Predicted Domain #1

Region A:
Residues: [1-173]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVILGIDPG SRVTGYGVIR QQGRHLIYLG SGCIRTSDLE LPLRLKQIYA GVSEIITQFQ  60
   61 PDAFAIEQVF MAKNADSALK LGQARGSAIV AAVNAELPVY EYAARLIKQA VVGTGAADKS 120
  121 QVQHMVQQML KLPGKPQADA ADALGVAICH ANTNKTLIAL AGQATSARRG RYR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.69897
Match:	1hjrA
Description:	RuvC resolvase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
exonuclease activity	2.2254764376369	bayes_pls_golite062009
nuclease activity	2.17358374135419	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.75713164321634	bayes_pls_golite062009
hydrolase activity	1.52863974928789	bayes_pls_golite062009
catalytic activity	1.25233849524628	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1.19309748194103	bayes_pls_golite062009
deoxyribonuclease activity	1.1219517187744	bayes_pls_golite062009
ribonuclease activity	0.901073799675851	bayes_pls_golite062009
DNA polymerase activity	0.717600245625866	bayes_pls_golite062009
DNA-directed DNA polymerase activity	0.568273228950698	bayes_pls_golite062009
endonuclease activity	0.527074808116937	bayes_pls_golite062009
exodeoxyribonuclease activity	0.278838342302102	bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters	0.261428436029202	bayes_pls_golite062009
binding	0.122249780594036	bayes_pls_golite062009
3'-5' exonuclease activity	0.115254148049348	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: