YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|57167421, gi\|...
Organism:	Campylobacter jejuni RM1221
Length:	207 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|57167421, gi|....

Description	E-value	Query Range	Subject Range
gi\|116220453, gi... - gi\|75819710\|ref\|ZP_00749778.1\| COG0139: Phosphoribosyl-AMP cyclohydrolase [Vibrio cholerae V51], gi\|...	306.0	[0..4]	[206..7]
gi\|229370940, gi... - gi\|229608285\|ref\|YP_002878933.1\| phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatas... HIS2_VIBCH - Histidine biosynthesis bifunctional protein HisIE OS=Vibrio cholerae GN=hisI PE=3 SV=1 gi\|121587405, gi... - gi\|121587405\|ref\|ZP_01677174.1\| phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase... gi\|124119019, gi... - gi\|153222277\|ref\|ZP_01953037.1\| phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase... gi\|126512535, gi... - gi\|153816948\|ref\|ZP_01969615.1\| phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase... gi\|126520460, gi... - gi\|229511064\|ref\|ZP_04400543.1\| phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase... gi\|75826492, gi\|... - gi\|75826492\|ref\|ZP_00755927.1\| COG0139: Phosphoribosyl-AMP cyclohydrolase [Vibrio cholerae O395], gi... gi\|121631238, gi... - gi\|75817342\|ref\|ZP_00747794.1\| COG0139: Phosphoribosyl-AMP cyclohydrolase [Vibrio cholerae V52], gi\|... gi\|227081312, gi... - gi\|227081312\|ref\|YP_002809863.1\| phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolas... gi\|229505266, gi... - gi\|229505266\|ref\|ZP_04394776.1\| phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase... HIS2_VIBCH - Histidine biosynthesis bifunctional protein HisIE OS=Vibrio cholerae serotype O1 (strain ATCC 39315 ... gi\|229518184, gi... - gi\|229518184\|ref\|ZP_04407628.1\| phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase... gi\|197751091, gi... - gi\|254291564\|ref\|ZP_04962354.1\| phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase... gi\|229520431, gi... - gi\|229520431\|ref\|ZP_04409856.1\| phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase... gi\|148875861, gi... - gi\|153828708\|ref\|ZP_01981375.1\| phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase... gi\|229339331, gi... - gi\|229525750\|ref\|ZP_04415155.1\| phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase... gi\|116188983, gi... - gi\|75830132\|ref\|ZP_00759416.1\| COG0139: Phosphoribosyl-AMP cyclohydrolase [Vibrio cholerae MO10], gi... gi\|149740251, gi... - gi\|153826031\|ref\|ZP_01978698.1\| phosphoribosyl-ATP pyrophosphatase/phosphoribosyl-AMP cyclohydrolase... gi\|229333546, gi... - gi\|229529772\|ref\|ZP_04419162.1\| phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase...	306.0	[0..4]	[206..7]
tr\|D7H7Y7\|D7H7Y7... - Histidine biosynthesis bifunctional protein HisIE OS=Vibrio cholerae RC385 GN=hisI PE=3 SV=1 gi\|254223617, gi... - gi\|75823475\|ref\|ZP_00752973.1\| COG0139: Phosphoribosyl-AMP cyclohydrolase [Vibrio cholerae RC385], g...	305.0	[0..4]	[206..7]
HIS2_CALS4 - Histidine biosynthesis bifunctional protein HisIE OS=Caldanaerobacter subterraneus subsp. tengcongen... HIS2_THETN - Histidine biosynthesis bifunctional protein hisIE OS=Thermoanaerobacter tengcongensis GN=hisI PE=3 S...	300.0	[0..8]	[206..4]
gi\|75704839, gi\|... - gi\|75911114\|ref\|YP_325410.1\| bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrop...	300.0	[0..9]	[206..16]
gi\|25290311 - pir\|\|AH2213 histidine biosynthesis bifunctional protein (phosphoribosyl-AMP cyclohydrolase/phosphor... HIS2_NOSS1 - Histidine biosynthesis bifunctional protein HisIE OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=his...	300.0	[0..9]	[206..16]
gi\|56752110, gi\|... - gi\|56752110\|ref\|YP_172811.1\| bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrop... gi\|81300804, gi\|... - gi\|81300804\|ref\|YP_401012.1\| bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrop...	299.0	[0..8]	[206..10]
gi\|76795717, gi\|... - gi\|76795717\|ref\|ZP_00778089.1\| Phosphoribosyl-AMP cyclohydrolase:Phosphoribosyl-ATP pyrophosphohydro... gi\|241904119, gi... - gi\|241904119\|ref\|ZP_04788828.1\| phosphoribosyl-ATP diphosphatase [Thermoanaerobacter brockii subsp. ...	299.0	[0..8]	[204..4]
gi\|167039657, gi... - gi\|167039657\|ref\|YP_001662642.1\| bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP p... gi\|242231370, gi... - gi\|242257128\|ref\|ZP_04802003.1\| phosphoribosyl-ATP diphosphatase [Thermoanaerobacter sp. X513], gi\|2...	298.0	[0..8]	[204..4]
gi\|56911050, gi\|... - gi\|56964807\|ref\|YP_176538.1\| bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrop...	298.0	[0..11]	[207..4]

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Predicted Domain #1

Region A:
Residues: [1-111]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNFKELNEK IAWQKVDNLL PVIIQDAKTC EVLMLGFMNN EALEKSLESG KVVFFSRTKQ  60
   61 RLWMKGEESG NFLNIIDLSL DCDNDTLLIL ANPVGPTCHT GDISCFEKIS K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.522879
Match:	1zpsA
Description:	Crystal structure of Methanobacterium thermoautotrophicum phosphoribosyl-AMP cyclohydrolase HisI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoribosyl-AMP cyclohydrolase activity	4.150200144507	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2.23740731288751	bayes_pls_golite062009
catalytic activity	1.39985329737364	bayes_pls_golite062009
cyclohydrolase activity	0.79104127517031	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	0.54834173729282	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [112-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NADFVFLARL EKLINARKNA DENTSYTAKL FKSGTKRIAQ KVGEEGVETA LAATVKDKEE  60
   61 LICEAADLMY HLSVLLADAN LSFSDVISKL KERHKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.09691
Match:	1yvwA
Description:	Crystal structure of Phosphoribosyl-ATP pyrophosphohydrolase from Bacillus cereus. NESGC target BcR13.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoribosyl-ATP diphosphatase activity	3.7001994388833	bayes_pls_golite062009
phosphoribosyl-AMP cyclohydrolase activity	2.61820126109961	bayes_pls_golite062009
catalytic activity	1.00486703080234	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.72725441841528	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: