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Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2. Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring. Catalysis of the reaction: 1-(5-phosphoribosyl)-AMP + H2O = 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: phosphoribosyl-AMP cyclohydrolase activity
Acc: GO:0004635
Aspect: Molecular Function
Desc: Catalysis of the reaction: 1-(5-phosphoribosyl)-AMP + H2O = 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide.
Synonyms:
  • 1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase activity
  • PRAMP-cyclohydrolase activity
  • phosphoribosyladenosine monophosphate cyclohydrolase activity
Proteins in PDR annotated with:
   This term: 13 [Search]
   Term or descendants: 13 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004635 - phosphoribosyl-AMP cyclohydrolase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle