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View Structure Prediction Details

Protein: gi|60819920, gi|...
Organism: synthetic construct
Length: 480 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|60819920, gi|....

Description E-value Query
Range		 Subject
Range
gi|210068 - gi|210068|gb|AAA42545.1| gag:akt fusion protein [AKT8 retrovirus]
gi|538540 - gi|538540|pir||A40831 gag-akt polyprotein - AKT8 murine leukemia virus
 494.0 [0..1] [480..284]
AKT1_BOVIN - RAC-alpha serine/threonine-protein kinase OS=Bos taurus GN=AKT1 PE=1 SV=2
 484.0 [0..1] [480..1]
gi|60831242 - gi|60831242|gb|AAX36962.1| v-akt murine thymoma viral oncogene-like 1 [synthetic construct]
 483.0 [0..1] [480..1]
AKT1_MOUSE - RAC-alpha serine/threonine-protein kinase OS=Mus musculus GN=Akt1 PE=1 SV=2
gi|117616188, gi... - gi|117616190|gb|ABK42113.1| AKT [synthetic construct], gi|117616188|gb|ABK42112.1| Akt1 [synthetic c...
 483.0 [0..1] [480..1]
AKT1_RAT - RAC-alpha serine/threonine-protein kinase OS=Rattus norvegicus GN=Akt1 PE=1 SV=1
 482.0 [0..1] [480..1]
AKT1 - v-akt murine thymoma viral oncogene homolog 1
gi|190690397, gi... - gi|208965678|dbj|BAG72853.1| v-akt murine thymoma viral oncogene homolog 1 [synthetic construct], gi...
 482.0 [0..1] [480..1]
gi|109085002, gi... - gi|109085002|ref|XP_001085746.1| PREDICTED: v-akt murine thymoma viral oncogene homolog 1 isoform 5 ...
 481.0 [0..1] [480..1]

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Predicted Domain #1
Region A:
Residues: [1-89] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDVAIVKEG WLHKRGEYIK TWRPRYFLLK NDGTFIGYKE RPQDVDQREA PLNNFSVAQC  60
   61 QLMKTERPRP NTFIIRCLQW TTVIERTFH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.69897
Match: 1h10A
Description: Rac-alpha serine/threonine kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [90-417] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VETPEEREEW TTAIQTVADG LKKQEEEEMD FRSGSPSDNS GAEEMEVSLA KPKHRVTMNE  60
   61 FEYLKLLGKG TFGKVILVKE KATGRYYAMK ILKKEVIVAK DEVAHTLTEN RVLQNSRHPF 120
  121 LTALKYSFQT HDRLCFVMEY ANGGELFFHL SRERVFSEDR ARFYGAEIVS ALDYLHSEKN 180
  181 VVYRDLKLEN LMLDKDGHIK ITDFGLCKEG IKDGATMKTF CGTPEYLAPE VLEDNDYGRA 240
  241 VDWWGLGVVM YEMMCGRLPF YNQDHEKLFE LILMEEIRFP RTLGPEAKSL LSGLLKKDPK 300
  301 QRLGGGSEDA KEIMQHRFFA GIVWQHVY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.39794
Match: 2pziA
Description: No description for 2pziA was found.

Predicted Domain #3
Region A:
Residues: [418-480] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKKLSPPFKP QVTSETDTRY FDEEFTAQMI TITPPDQDDS MECVDSERRP HFPQFSYSAS  60
   61 STA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 96.69897
Match: 1mrvA
Description: crystal structure of an inactive Akt2 kinase domain
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle