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View Structure Prediction Details

Protein: gi|61355068, gi|...
Organism: synthetic construct
Length: 115 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|61355068, gi|....

Description E-value Query
Range
Subject
Range
MIF_MOUSE - Macrophage migration inhibitory factor OS=Mus musculus GN=Mif PE=1 SV=2
6.0E-54 [1..115] [1..115]
gi|7514124, gi|6... - gi|7514124|pir||I52370 macrophage migration inhibitory factor MIF [similarity] - rat, gi|663140|gb|A...
MIF_RAT - Macrophage migration inhibitory factor OS=Rattus norvegicus GN=Mif PE=1 SV=4
1.0E-53 [1..115] [1..115]
gi|49659870, gi|... - gi|50881974|gb|AAT85562.1| BS011P [Gekko japonicus], gi|49659870|gb|AAT68234.1| GekBS032P [Gekko jap...
MIF_PIG - Macrophage migration inhibitory factor OS=Sus scrofa GN=MIF PE=1 SV=3
8.0E-53 [1..115] [1..115]
MIF_MERUN - Macrophage migration inhibitory factor OS=Meriones unguiculatus GN=MIF PE=3 SV=3
1.0E-52 [1..115] [1..115]
MIF_BOVIN - Macrophage migration inhibitory factor OS=Bos taurus GN=MIF PE=1 SV=6
MIF_SHEEP - Macrophage migration inhibitory factor OS=Ovis aries GN=MIF PE=3 SV=1
1.0E-52 [1..115] [1..115]
gi|30585217, gi|... - gi|61365201|gb|AAX42670.1| macrophage migration inhibitory factor [synthetic construct], gi|60825453...
4.0E-52 [1..115] [1..115]

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Predicted Domain #1
Region A:
Residues: [1-115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF GGSSEPCALC  60
   61 SLHSIGKIGG AQNRSYSKLL CGLLAERLRI SPDRVYINYY DMNAANVGWN NSTFA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.522879
Match: 1mfiA
Description: Microphage migration inhibition factor (MIF)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phenylpyruvate tautomerase activity 3.84932786282501 bayes_pls_golite062009
cytokine activity 2.80410252537768 bayes_pls_golite062009
intramolecular oxidoreductase activity 2.17252244354636 bayes_pls_golite062009
binding 1.9717928129965 bayes_pls_golite062009
receptor binding 1.79096938850925 bayes_pls_golite062009
protein binding 1.70051621352839 bayes_pls_golite062009
catalytic activity 0.836951613125537 bayes_pls_golite062009
isomerase activity 0.804529932513639 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing C=C bonds 0.452407074010503 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle