YRC Public Data Repository - Protein Structure Prediction

Protein:	PRP18_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	343 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PRP18_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|47216030 - gi\|47216030\|emb\|CAG11361.1\| unnamed protein product [Tetraodon nigroviridis]	248.0	[0..47]	[339..4]
gi\|26331594 - gi\|26331594\|dbj\|BAC29527.1\| unnamed protein product [Mus musculus]	233.0	[0..175]	[339..24]
gi\|55242489, gi\|... - gi\|58383641\|ref\|XP_312664.2\| ENSANGP00000020655 [Anopheles gambiae str. PEST], gi\|55242489\|gb\|EAA074...	224.0	[0..47]	[339..4]
Prp18-PA - The gene Prp18 is referred to in FlyBase by the symbol Dmel\Prp18 (CG6011, FBgn0027784). It is a pro... gi\|220953712, gi... - gi\|220953712\|gb\|ACL89399.1\| Prp18-PA [synthetic construct], gi\|220943810\|gb\|ACL84448.1\| Prp18-PA [sy...	216.0	[0..46]	[339..2]
gi\|50918041, gi\|... - gi\|62733528\|gb\|AAX95645.1\| Prp18 domain, putative [Oryza sativa (japonica cultivar-group)], gi\|50918...	214.0	[0..105]	[339..194]
gi\|54637510\|gb\|E... - GA19293-PA [Drosophila pseudoobscura], GA19293 [Drosophila pseudoobscura pseudoobscura] gi\|54637510, gi\|... - gi\|54637510\|gb\|EAL26912.1\| GA19293 [Drosophila pseudoobscura pseudoobscura], gi\|125773037\|ref\|XP_001... gi\|195158873, gi... - gi\|195158873\|ref\|XP_002020309.1\| GL13914 [Drosophila persimilis], gi\|194117078\|gb\|EDW39121.1\| GL1391...	209.0	[0..46]	[339..2]
gi\|157118813, gi... - gi\|157118813\|ref\|XP_001653273.1\| pre-mrna processing factor [Aedes aegypti], gi\|108875585\|gb\|EAT3981...	208.0	[0..48]	[339..4]
PRP18_RAT - Pre-mRNA-splicing factor 18 OS=Rattus norvegicus GN=Prpf18 PE=2 SV=1	207.0	[0..1]	[339..1]

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Predicted Domain #1

Region A:
Residues: [1-255]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFLKEEIER KRRQLEGTSE LPVKKAFRRG DWEKEREKKY LQEKQQKDEQ RELKKRKLEE  60
   61 ERLKYEEKKL RISRLANKES SRNEELLTET TTPSPAVKAS PASTKLSVSE NDRLSIPEIT 120
  121 KDNLTLTEII AKLREMKEPI RLFGESEEAT IQRYYSLLKY KKLEEIENEL LTKGVETIDF 180
  181 EHATTTKPKV SKQVVAFLQH GIRIWDNFLS SKSINSFESS ESQMQLKIFR QAKQDLDVLI 240
  241 QLIVDEALND DIFKS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	6.39794
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [256-343]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IAEICYRCQK HEFVKANDMY LRLTIGNAPW PIGVTMVGIH ERSAHQRLQA NPSSNILKDE  60
   61 KKRKCLQALK RFITFQERES SNLPEYTD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.0
Match:	1dvkA
Description:	Functional domain of the splicing factor Prp18
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits