YRC Public Data Repository - Protein Structure Prediction

Protein:	SERA_SCHPO
Organism:	Schizosaccharomyces pombe 972h-
Length:	466 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SERA_SCHPO.

Description	E-value	Query Range	Subject Range
gi\|44981411 - gi\|44981411\|gb\|AAS51196.1\| ACL032Cp [Ashbya gossypii ATCC 10895] gi\|44981411, gi\|... - gi\|45185656\|ref\|NP_983372.1\| ACL032Cp [Ashbya gossypii ATCC 10895], gi\|44981411\|gb\|AAS51196.1\| ACL03...	416.0	[0..8]	[466..17]
orf19.5263, orf1... - SER33 CGDID:CAL0003590 Assembly 19, Contig19-10223 (85946, 84555) CDS, reverse complemented, transla... gi\|68479177, gi\|... - gi\|68479306\|ref\|XP_716332.1\| hypothetical protein CaO19.5263 [Candida albicans SC5314], gi\|68479177\|... gi\|238878404 - gi\|238878404\|gb\|EEQ42042.1\| D-3-phosphoglycerate dehydrogenase 1 [Candida albicans WO-1]	415.0	[0..7]	[466..13]
gi\|190405645 - gi\|190405645\|gb\|EDV08912.1\| 3-phosphoglycerate dehydrogenase [Saccharomyces cerevisiae RM11-1a] SER3 - 3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozy... gi\|151944798 - gi\|151944798\|gb\|EDN63057.1\| 3-phosphoglycerate dehydrogenase [Saccharomyces cerevisiae YJM789] SERA_YEAST - D-3-phosphoglycerate dehydrogenase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SER...	412.0	[0..7]	[466..15]
gi\|50294980, gi\|... - gi\|50294980\|ref\|XP_449901.1\| hypothetical protein CAGL0M12837g [Candida glabrata CBS138], gi\|4952921... gi\|49529215 - gi\|49529215\|emb\|CAG62881.1\| unnamed protein product [Candida glabrata]	412.0	[0..7]	[466..12]
gi\|49641747, gi\|... - gi\|50305309\|ref\|XP_452614.1\| unnamed protein product [Kluyveromyces lactis], gi\|49641747\|emb\|CAH0146... gi\|49641747 - gi\|49641747\|emb\|CAH01465.1\| KLLA0C09306p [Kluyveromyces lactis]	406.0	[0..8]	[466..17]
gi\|85077261 - gi\|85077261\|ref\|XP_955999.1\| D-3-phosphoglycerate dehydrogenase 1 [Neurospora crassa OR74A] gi\|32414797, gi\|... - gi\|32414797\|ref\|XP_327878.1\| hypothetical protein [Neurospora crassa], gi\|28917038\|gb\|EAA26763.1\| D-...	398.0	[0..17]	[466..18]
gi\|115438570, gi... - gi\|115438570\|ref\|XP_001218100.1\| D-3-phosphoglycerate dehydrogenase 2 [Aspergillus terreus NIH2624],...	396.0	[0..18]	[466..16]
SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii GN=serA PE=3 SV=1 SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / ...	391.0	[0..57]	[463..3]
gi\|159126186 - gi\|159126186\|gb\|EDP51302.1\| D-3-phosphoglycerate dehydrogenase [Aspergillus fumigatus A1163] gi\|70998716, gi\|... - gi\|70998716\|ref\|XP_754080.1\| D-3-phosphoglycerate dehydrogenase [Aspergillus fumigatus Af293], gi\|66...	390.0	[0..7]	[466..12]

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Predicted Domain #1

Region A:
Residues: [1-466]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIKGGRRGN VEDSLNKLSL SPPDNNSSFL SNHFQVRKSY SQAPARTLKP FASEDIKILL  60
   61 LENVNQSALS NLKDEGYQVE FLKTSMSEDD LVEKIKGVHA IGIRSKTRLT RRVLEAADSL 120
  121 IVIGCFCIGT NQVDLDFAAE RGIAVFNSPY ANSRSVAELV IGYIISLARQ VGDRSLELHR 180
  181 GEWNKVSSGC WEIRGKTLGI IGYGHIGSQL SVLAEAMGLH VVYYDILPIM PLGSAKQLSS 240
  241 LPELLHRADF VSLHVPASPE TKNMISSKEF AAMKEGSYLI NASRGTVVDI PALVDASKSG 300
  301 KIAGAAIDVY PSEPAGNGKD KFVDSLNSWT SELTHCKNII LTPHIGGSTE EAQYNIGIEV 360
  361 SEALTRYINE GNSIGAVNFP EVSLRSLTEA DRNAARVLFV HRNVPGVLRQ VNELFIDHNI 420
  421 KSQFSDSRGD IAYLVADISD CTPGSLEALH QKLESLPCKI NTRLLY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	94.30103
Match:	1psdA
Description:	Phosphoglycerate dehydrogenase; Phosphoglycerate dehydrogenase, regulatory (C-terminal) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	3.48670706716817	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.27460110663386	bayes_pls_golite062009
oxidoreductase activity	1.69771604880532	bayes_pls_golite062009
alcohol dehydrogenase (NAD) activity	1.68027744358887	bayes_pls_golite062009
binding	1.09846595911524	bayes_pls_golite062009
alcohol dehydrogenase activity, zinc-dependent	0.839863523675468	bayes_pls_golite062009
catalytic activity	0.645256181736122	bayes_pls_golite062009
phosphoglycerate dehydrogenase activity	0.639509916626856	bayes_pls_golite062009
transferase activity	0.576589833246962	bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors	0.418775403210681	bayes_pls_golite062009
transcription regulator activity	0.402429890233999	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	0.32207755075663	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.310712203379158	bayes_pls_golite062009
protein binding	0.219210115869644	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: