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View Structure Prediction Details

Protein: TF3B_SCHPO
Organism: Schizosaccharomyces pombe 972h-
Length: 500 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TF3B_SCHPO.

Description E-value Query
Range
Subject
Range
BRF1 - BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)
383.0 [0..6] [494..1]
TF3B_MOUSE - Transcription factor IIIB 90 kDa subunit OS=Mus musculus GN=Brf1 PE=1 SV=1
383.0 [0..6] [494..1]
gi|109480055, gi... - gi|62651305|ref|XP_216801.3| PREDICTED: similar to transcription initiation factor IIIB [Rattus norv...
382.0 [0..6] [494..1]
gi|28422474, gi|... - gi|41054023|ref|NP_956192.1| BRF1 homolog, subunit of RNA polymerase III transcription initiation fa...
361.0 [0..10] [494..3]
gi|52354750, gi|... - gi|52354750|gb|AAH82860.1| LOC494758 protein [Xenopus laevis], gi|162287069|ref|NP_001088063.1| hypo...
350.0 [0..6] [494..1]
gi|114655135 - gi|114655135|ref|XP_510208.2| PREDICTED: transcription initiation factor IIIB [Pan troglodytes]
341.0 [0..71] [494..209]

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Predicted Domain #1
Region A:
Residues: [1-66]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLCFQLFAMG CPNCGSTTFE SDTASGNTYC TQCGVVVEQD AIVSEVTFGE ASTGAAVVQG  60
   61 SLVSND

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [67-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QTHARTFGGP YRNQGSVESR ELTIANGRRR ISALAIALKL NERHIEAAVR YFTLAINNNF  60
   61 IKGRRSQYVV ASCLYIVCRI SKTSHMLIDF SDILQINVFK LGSTFLKLCR VLRPNLPLLD 120
  121 PSLYISRFAS LLEFGPETHR VANDAIRLVA RMNRDWMQIG RRPAGICGAC LLIAARMNNF 180
  181 RRSVREVVHV VKVADITIQK RLDEFKLTES GDLSIA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.0
Match: 2b9rA
Description: No description for 2b9rA was found.

Predicted Domain #3
Region A:
Residues: [283-368]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFRNIWLEGQ SDPPSFTKNQ KFQQYGAQKV SNIDHTQEYM SPIKRTPDFD GNEVKSEELS  60
   61 QTVKVESQET PVHLKADERE IRKEVT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [369-500]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ETLKGDELRK ISLQVNVKFS EEEVTLEDVD DDEIEDILLD KDEILTKTQV WMELNKDYLA  60
   61 EEEAKNLKLQ EDLKKGIVRQ PRKRRRYRPR DSTSDGIADT AAESAKEMMQ QRAFSKKINY 120
  121 EALDMLFDEE QS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.045757
Match: 1ngmB
Description: TBP-binding domain of the transcription factor IIIb Brf1 subunit
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle