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View Structure Prediction Details

Protein: sma-4
Organism: Caenorhabditis elegans
Length: 189 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sma-4.

Description E-value Query
Range
Subject
Range
gi|157137978, gi... - gi|157137978|ref|XP_001664103.1| smad4 [Aedes aegypti], gi|108869602|gb|EAT33827.1| smad4 [Aedes aeg...
245.0 [0..1] [188..473]

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Predicted Domain #1
Region A:
Residues: [1-189]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPHGENEGR LCLGALSNVH RTEASEKARI HIGRGVELTA HADGNISITS NCKIFVRSGY  60
   61 LDYTHGSEYS SKAHRFTPNE SSFTVFDIRW AYMQMLRRSR SSNEAVRAQA AAVAGYAPMS 120
  121 VMPAIMPDSG VDRMRRDFCT IAISFVKAWG DVYQRKTIKE TPCWIEVTLH RPLQILDQLL 180
  181 KNSSQFGSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.221849
Match: 1mr1A
Description: Smad4 tumor suppressor C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.962970280214435 bayes_pls_golite062009
protein binding 0.56456434217804 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle